Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)commu...Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)communication.However,the lack of an efficient UV photodetection methodology hinders the development of UV-based communication.The key technological impediment is related to the low UV-photon absorption in existing silicon photodetectors,which offer low-cost and mature platforms.To address this technology gap,we report a hybrid Sibased photodetection scheme by incorporating CsPbBr_(3) perovskite nanocrystals(NCs)with a high photoluminescence quantum yield(PLQY)and a fast photoluminescence(PL)decay time as a UV-to-visible colourconverting layer for high-speed solar-blind UV communication.The facile formation of drop-cast CsPbBr_(3) perovskite NCs leads to a high PLQY of up to ~73% and strong absorption in the UV region.With the addition of the NC layer,a nearly threefold improvement in the responsivity and an increase of ~25% in the external quantum efficiency(EQE)of the solar-blind region compared to a commercial silicon-based photodetector were observed.Moreover,timeresolved photoluminescence measurements demonstrated a decay time of 4.5 ns under a 372-nm UV excitation source,thus elucidating the potential of this layer as a fast colour-converting layer.A high data rate of up to 34 Mbps in solar-blind communication was achieved using the hybrid CsPbBr_(3)-silicon photodetection scheme in conjunction with a 278-nm UVC light-emitting diode(LED).These findings demonstrate the feasibility of an integrated high-speed photoreceiver design of a composition-tuneable perovskite-based phosphor and a low-cost silicon-based photodetector for UV communication.展开更多
The use of a biodegradable natural plant-based surfactant extracted from soapberry is proposed for the remediation of Ni, Cr and Mn from industrial soil site in Hai-Pu, Taiwan. Batch experiments were performed under v...The use of a biodegradable natural plant-based surfactant extracted from soapberry is proposed for the remediation of Ni, Cr and Mn from industrial soil site in Hai-Pu, Taiwan. Batch experiments were performed under variation of fundamental factors （saponin concentration, pH, and incubation time） for metal remediation. Removal of Ni and Mn were increased with increasing saponin concentration （0.015-0.150 g/L）, whereas the removal of Cr was increased upto 0.075 g/L saponin. The Ni, Cr and Mn were removed significantly （p 〈 0.05） at near to the neutral and slightly acidic （pH 5 to 8） conditions. Removal efficiency of Ni （99%） from the soil was found to be greater than that of Cr （73%） or Mn （25%） in the presence of saponin at a concentration of 0.150 g/L at pH 5. The removal percentage increased with incubation time where the removal of Ni was faster than that of Cr and Mn. The result indicates the feasibility of cco-friendly removal of heavy metal （Ni, Cr and Mn） from industrial soil by soil washing process in presence of plant derived saponin.展开更多
Grain growth kinetics of austenite in a hypoeutectoid steel（containing carbon of 0.35%）at 920 ℃ and in a hypereutectoid steel（containing carbon of 1%）at 980 ℃ for holding time ranging from 1 h to 6 h was investi...Grain growth kinetics of austenite in a hypoeutectoid steel（containing carbon of 0.35%）at 920 ℃ and in a hypereutectoid steel（containing carbon of 1%）at 980 ℃ for holding time ranging from 1 h to 6 h was investigated.The hypoeutectoid steel exhibited normal grain growth without solute drag hindrance with a time exponent（0.51）close to the theoretical value（0.5）.However,the grain growth of austenite in the hypereutectoid steel held up to 3 h was extremely slow,characterizing by a low value of time exponent（0.08）.Thereafter,a breakaway occurred and the grain growth in the hypereutectoid steel held from 3 h to 6 h progressed normally with a time exponent（0.52）close to the theoretical value（0.5）.展开更多
Confocal laser endomicroscopy(CLE)is a novel endoscopic modality that provides real-time histological information via high-resolution magnified view of the mucosa.CLE has a higher sensitivity,specificity,and diagnosti...Confocal laser endomicroscopy(CLE)is a novel endoscopic modality that provides real-time histological information via high-resolution magnified view of the mucosa.CLE has a higher sensitivity,specificity,and diagnostic accuracy in detecting atrophic gastritis as compared to chromoendoscopy and narrow-band imaging.It can even predict low-grade and high-grade intraepithelial neoplasia by analyzing gastric pit patterns.CLE may have some advantages over the standard biopsy protocol,such as higher diagnostic yield and fewer biopsy requirements.Its diagnostic accuracy in detecting superficial gastric cancer is higher than that of white-light endoscopy.Inherent limitations,such as a narrow field of vision,can be surpassed by technological advancements and integration with other detection methods.Artificial intelligence holds promise in automated analysis of histopathological images.Thus,CLE can be helpful in screening for early gastric cancer and may help reduce the risk of complications from repeated biopsies,such as mucosal damage,bleeding,and infection.展开更多
Rapid urbanization creates complexity,results in dynamic changes in land and environment,and influences the land surface temperature(LST)in fast-developing cities.In this study,we examined the impact of land use/land ...Rapid urbanization creates complexity,results in dynamic changes in land and environment,and influences the land surface temperature(LST)in fast-developing cities.In this study,we examined the impact of land use/land cover(LULC)changes on LST and determined the intensity of urban heat island(UHI)in New Town Kolkata(a smart city),eastern India,from 1991 to 2021 at 10-a intervals using various series of Landsat multi-spectral and thermal bands.This study used the maximum likelihood algorithm for image classification and other methods like the correlation analysis and hotspot analysis(Getis–Ord Gi^(*) method)to examine the impact of LULC changes on urban thermal environment.This study noticed that the area percentage of built-up land increased rapidly from 21.91%to 45.63%during 1991–2021,with a maximum positive change in built-up land and a maximum negative change in sparse vegetation.The mean temperature significantly increased during the study period(1991–2021),from 16.31℃to 22.48℃in winter,29.18℃to 34.61℃in summer,and 19.18℃to 27.11℃in autumn.The result showed that impervious surfaces contribute to higher LST,whereas vegetation helps decrease it.Poor ecological status has been found in built-up land,and excellent ecological status has been found in vegetation and water body.The hot spot and cold spot areas shifted their locations every decade due to random LULC changes.Even after New Town Kolkata became a smart city,high LST has been observed.Overall,this study indicated that urbanization and changes in LULC patterns can influence the urban thermal environment,and appropriate planning is needed to reduce LST.This study can help policy-makers create sustainable smart cities.展开更多
The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 3...The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.展开更多
AIM:To evaluate if topical use ofαB-crystallin minipeptides supports corneal healing following flap surgery.METHODS:Cultured corneal cells were treated with fluorescent taggedαB-crystallin mini-peptides to assess it...AIM:To evaluate if topical use ofαB-crystallin minipeptides supports corneal healing following flap surgery.METHODS:Cultured corneal cells were treated with fluorescent taggedαB-crystallin mini-peptides to assess its internalization.Cultured corneal cells pre-treated with or without the mini-peptides were exposed to H2O2 and cell viability was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.Elongation of neurites of cultured trigeminal neurones was examined following treatment either withαB-crystallin mini-peptides or protein.Cultured trigeminal neurones were pre-treated either withαB-crystallin mini-peptides or crystallin protein and exposed to H2O2 and presence of beading in the dendrites and axons was assessed.Corneal flap surgery was conducted on rabbit cornea and treated topically either withαB-crystallin peptide(0.5 mg/mL thrice daily for 14d)or phosphate-buffered saline(PBS).Corneal healing was evaluated under slit-lamp biomicroscope,mRNA expression of inflammatory cytokines were assessed and the corneas were evaluated by histopathology.RESULTS:Internalization ofαB-crystallin mini-peptides was ascertained by the detection of fluorescence within the corneal cells.The MTT assay revealed that treatment withαB-crystallin mini-peptide reduced cell death induced by H2O2 treatment.The mini-peptides did not influence the elongation of trigeminal neurites,but significantly(P<0.05)reduced beading in the neurites.In rabbit eye,the treated corneas showed reduced hyper-reflective zones(P<0.05)and suppression in the expression of inflammatory cytokines.Histopathological examination also revealed reduction of inflammatory response in treated corneas.CONCLUSION:TheαB-crystallin mini-peptides restrict the damage to corneal cells and neurons and aids in corneal healing.展开更多
Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)is a common medical emergency in clinical practice.While the incidence has significantly reduced,the mortality rates have not undergone a similar reduction in...Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)is a common medical emergency in clinical practice.While the incidence has significantly reduced,the mortality rates have not undergone a similar reduction in the last few decades,thus presenting a significant challenge.This editorial outlines the key causes and risk factors of ANVUGIB and explores the current standards and recent updates in risk assessment scoring systems for predicting mortality and endoscopic treatments for achieving hemostasis.Since ANUVGIB predominantly affects the elderly population,the impact of comorbidities may be responsible for the poor outcomes.A thorough drug history is important due to the increasing use of antiplatelet agents and anticoagulants in the elderly.Early risk stratification plays a crucial role in deciding the line of management and predicting mortality.Emerging scoring systems such as the ABC(age,blood tests,co-morbidities)score show promise in predicting mortality and guiding clinical decisions.While conventional endoscopic therapies remain cornerstone approaches,novel techniques like hemostatic powders and over-the-scope clips offer promising alternatives,particularly in cases refractory to traditional modalities.By integrating validated scoring systems and leveraging novel therapeutic modalities,clinicians can enhance patient care and mitigate the substantial morbidity and mortality associated with ANVUGIB.展开更多
BACKGROUND There are indications that viral myocarditis,demand ischemia,and renin-angio-tensin-aldosterone system pathway activation play essential roles in troponin elevation in coronavirus disease 2019(COVID-19)pati...BACKGROUND There are indications that viral myocarditis,demand ischemia,and renin-angio-tensin-aldosterone system pathway activation play essential roles in troponin elevation in coronavirus disease 2019(COVID-19)patients.Antiviral medications and steroids are used to treat viral myocarditis,but their effect in patients with elevated troponin,possibly from myocarditis,has not been studied.AIM To evaluate the effect of dexamethasone,remdesivir,and angiotensin-converting enzyme(ACE)inhibitors(ACEI)on mortality in COVID-19 patients with elevated troponin.METHODS Our retrospective observational study involved 1788 COVID-19 patients at seven hospitals in Southern California,United States.We did a backward selection Cox multivariate regression analysis to determine predictors of mortality in our study population.Additionally,we did a Kaplan Meier survival analysis in the subset of patients with elevated troponin,comparing survival in patients that received dexamethasone,remdesivir,and ACEI with those that did not.RESULTS The mean age was 66 years(range 20-110),troponin elevation was noted in 11.5%of the patients,and 29.9%expired.The patients'age[hazard ratio(HR)=1.02,P<0.001],intensive care unit admission(HR=5.07,P<0.001),and ventilator use(HR=0.68,P=0.02)were significantly associated with mortality.In the subset of patients with elevated troponin,there was no statistically significant difference in survival in those that received remdesivir(0.07),dexamethasone(P=0.63),or ACEI(P=0.8)and those that did not.CONCLUSION Although elevated troponin in COVID-19 patients has been associated with viral myocarditis and ACE II receptors,conventional viral myocarditis treatment,including antiviral and steroids,and ACEI did not show any effect on mortality in these patients.展开更多
Present study deals with the straight impact of hypobaric hypoxia on the quantity and composition of some predominant fecal microflora and its functional aspects. For that, isolated fecal contents of rat were exposed ...Present study deals with the straight impact of hypobaric hypoxia on the quantity and composition of some predominant fecal microflora and its functional aspects. For that, isolated fecal contents of rat were exposed to two different simulated air pressures （70 kPa and 40 kPa） for different time durations （1, 3, and 5 h） and the bacterial community composition was compared with normobaric groups （101.3 kPa）. It was found that the total anaerobes, Escherichio coli, Enterbocters spp., Bi^idobocterium spp., CIostridium spp. were increased whereas total aerobes were decreased at both hypobaric treatments. The increased number of amplicon was detected in the pressure-treated groups than the control that clearly mentioned the disruption of microbiota structure at different simulated hypobaric-hypoxia. The amylase, protease, tannase, 13-glucuronidase, and alkaline phosphatase activities were increased at these atmospheric pressures. Thus, the present investigation demonstrates that the hypobaric hypoxia is an important environmental factor which can strongly modulate the composition of intestinal flora as well as microfiora-derived functional aspects.展开更多
An investigation was carried out to modify the toughness of triethylene tetramine cured DGEBA （diglycidyl ether of bisphenol-A） resin using solid amine terminated poly （ethylene glycol） benzoate （ATPEGB） as modi...An investigation was carried out to modify the toughness of triethylene tetramine cured DGEBA （diglycidyl ether of bisphenol-A） resin using solid amine terminated poly （ethylene glycol） benzoate （ATPEGB） as modifier with and without red mud waste particles. The solid ATPEGB modifier synthesized from the acid catalyzed esterification reaction of poly （ethylene glycol） （PEG） and 4-amino benzoic acid was characterized by Fourier transform infrared spectroscopy （FT-IR） and ^1H-NMR （nuclear magnetic resonance） spectroscopies, viscosity measurements, and solubility parameter calculation. The unfilled and red mud waste filled modified epoxy networks were evaluated with impact, adhesive, tensile, flexural and thermal properties by differential scanning calorimetry （DSC）, thermogravimetric （TG） and dynamic mechanical analysis （DMA）. The effect of modifier concentration and red mud waste particles on toughening behavior was also investigated. The optimum properties were obtained at 12.5 phr （parts per hundred parts of resin） concentration of the modifier. The ATPEGB modified cured epoxy was thermally stable up to 315℃. The morphology on fracture surfaces of cured epoxy was also analyzed by scanning electron microscopy （SEM）.展开更多
The present work reviews different decision making tools(material comparing and choosing tools)used for selecting the best material considering different parameters.In this review work,the authors have tried to addres...The present work reviews different decision making tools(material comparing and choosing tools)used for selecting the best material considering different parameters.In this review work,the authors have tried to address the following important enquiries:1)the engineering applications addressed by the different material choosing and ranking methods;2)the predominantly used decision making tools addressing the optimal material selection for the engineering applications;3)merits and demerits of decision making tools used;4)the dominantly used criteria or objectives considered while selecting a suitable alternative material;5)overview of DEA on material selection field.The authors have surveyed literatures from different regions of the globe and considered literatures since 1988.The present review not only stresses the importance of material selection in the early design stage of the product development but also aids the design and material engineers to apply different decision making tools systematically.展开更多
In this study, a newly developed titanium superalloy, i.e., the Ti-5553 alloy has used for hot machining. This material replaced Ti-grade-5 alloy in the application of aerospace, automobile, and biomedical sector. How...In this study, a newly developed titanium superalloy, i.e., the Ti-5553 alloy has used for hot machining. This material replaced Ti-grade-5 alloy in the application of aerospace, automobile, and biomedical sector. However, similar to Ti-grade-5 alloy, the Ti-5553 alloy has a low thermal conductivity which makes it difficult-to-cut material categories hence, high tool wear, cutting force and bad surface finish. Hot machining of Ti-5553 has been studied at different machining condition (room and hot) using Deform-2D finite element analysis. The result from the simulation test was compared with the experimental value and reduction of cutting and thrust forces was observed. The experiment was carried out with the same input parameters as simulation, and good coherence between them observed. Additionally, cutting zone temperature, effective stress, etc. for both room and elevated the temperature are also discussed.展开更多
From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ exper...From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.展开更多
Cooperation in spectral sensing （SS） offers a fast and reliable detection of primary user （PU） transmission over a frequency spectrum at the expense of increased energy consumption. Since the fusion center （FC） ...Cooperation in spectral sensing （SS） offers a fast and reliable detection of primary user （PU） transmission over a frequency spectrum at the expense of increased energy consumption. Since the fusion center （FC） has to handle a large set of data, a duster based approach, specifically fuzzy c-means clustering （FCM）, has been extensively used in energy detection based cooperative spectrum sensing （CSS）. However, the performance of FCM degrades at low signal-to-noise ratios （SNR） and in the presence of multiple PUs as energy data patterns at the FC are often found to be non-spherical i.e. overlapping. To address the problem, this work explores the scope of kernel fuzzy c-means （KFCM） on energy detection based CSS through the projection of non-linear input data to a high dimensional feature space. Extensive simulation results are shown to highlight the improved detection of multiple PUs at low SNR with low energy consumption. An improvement in the detection probability by ～6.78% and ～6.96% at -15 dBW and -20 dBW, respectively, is achieved over the existing FCM method.展开更多
Four coal samples from Jharia basin,India are treated with nitric acid in glacial acetic acid and aqueous media to find out the chemical,petrographic and spatial structure of the organic mass by X-ray diffraction(XRD)...Four coal samples from Jharia basin,India are treated with nitric acid in glacial acetic acid and aqueous media to find out the chemical,petrographic and spatial structure of the organic mass by X-ray diffraction(XRD)and Fourier Transform Infrared Spectroscopy(FTIR)techniques.X-ray parameters of coal like interlayer spacing(d_(002)),crystallite size(L_(c)),aroamticity(f_(a)),average number of aromatic layers(N_(c)),and coal rank(I_(26)/I_(20))have been determined using profilefitting software.Considerable variation is observed in treated coals in comparison to the demineralized coals.The d_(002)values of treated coals have increased in both the media showing increase in disordering of organic moieties.A linear relationship has been observed between d_(002)values with the volatile matter of the coals.Similarly,the d_(002)values show linear relationship with C_(dmf) contents for demineralized as well as for the treated coals in both the media.The L_(c) and N_(c) values have decreased in treated coals corresponding to demineralized coals.The present study shows that nitration in both the media is capable of removing the aliphatic side chains from the coals and aromaticity(f_(a))increases with increase in rank and shows a linear relationship with the vitrinite reflectance.The corresponding I_(26)/I_(20)values are least for treated coals in glacial acetic acid medium followed by raw and then to treated coals in aqueous medium.FTIR studies show that coal arenes of the raw coals are converted into nitro-arenes in structurally modified coals(SMCs)in both the media,the corresponding bands at 1550-1490 and 1355-1315 cm^(-1) respectively.FTIR study confirms that nitration is the predominant phenomenon,though,oxidation and nitration phenomena takes place simultaneously during treatment with nitric acid to form SMCs.In comparison to raw coals,the SMCs show higher aromaticity and may be easily converted to coal derived products like activated carbon and specialty carbon materials.展开更多
In this paper, we consider three species harvesting model and develop a solution proce- dure which is able to calculate the equilibrium points of the model where some biological parameters of the model are interval nu...In this paper, we consider three species harvesting model and develop a solution proce- dure which is able to calculate the equilibrium points of the model where some biological parameters of the model are interval numbers. A parametric mathematical program is formulated to find the biological equilibrium of the model for different values of parame- ters. This interval-valued problem is converted into equivalent crisp model using interval operations. The main advantage of the proposed procedure is that we can present dif- ferent characteristics of the model in a single framework. Analytically, the existence of steady state and stabilities are looked into. Using mathematical software, the model is illustrated and the results are obtained and presented in tabular and graphical forms.展开更多
Objective:To investigate hepatoprotective activity of ethanol extract of Melothria heterophyila Lour Cogn.（EEMH） against CCl<sub>4</sub>-induced hepatic damage in rats.Methods:β-sitosterol was isolated ...Objective:To investigate hepatoprotective activity of ethanol extract of Melothria heterophyila Lour Cogn.（EEMH） against CCl<sub>4</sub>-induced hepatic damage in rats.Methods:β-sitosterol was isolated by column chromatography and characterized spectroscopically.Two different doses（200 and 400 mg/kg bw） of EEMH were administered orally in alternate days.The hepatoprotective activity was studied in liver by measuring biochemical parameters such as serum aspartate amino transferase（AST）,alanine amino transferase（ALT）,alkaline phosphatase（ALP）,total protein and total bilirubin.Lipid peroxidation product and different antioxidant enzyme activities were assessed in liver homogenate.Results:EEMH reduced all biochemical parameters and lipid peroxidation,as well as it increased the antioxidant enzyme activities in comparison with silymarin.The protective effect of the extract on CCl<sub>4</sub> induced damage was confirmed by histopathological examination of the liver.Conclusions:This result strongly supports the protective effect of EEMH against acute liver injury,and may be attributed to its antioxidative activity.展开更多
基金supported by funding from King Abdullah University of Science and Technology(KAUST),BAS/1/1614-01-01,KCR/1/2081-01-01 and GEN/1/6607-01-01,and the KAUST-KFUPM Special Initiative,REP/1/2878-01-01the financial support from the King Abdulaziz City for Science and Technology(KACST),Grant no.KACST TIC R2-FP-008.
文摘Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)communication.However,the lack of an efficient UV photodetection methodology hinders the development of UV-based communication.The key technological impediment is related to the low UV-photon absorption in existing silicon photodetectors,which offer low-cost and mature platforms.To address this technology gap,we report a hybrid Sibased photodetection scheme by incorporating CsPbBr_(3) perovskite nanocrystals(NCs)with a high photoluminescence quantum yield(PLQY)and a fast photoluminescence(PL)decay time as a UV-to-visible colourconverting layer for high-speed solar-blind UV communication.The facile formation of drop-cast CsPbBr_(3) perovskite NCs leads to a high PLQY of up to ~73% and strong absorption in the UV region.With the addition of the NC layer,a nearly threefold improvement in the responsivity and an increase of ~25% in the external quantum efficiency(EQE)of the solar-blind region compared to a commercial silicon-based photodetector were observed.Moreover,timeresolved photoluminescence measurements demonstrated a decay time of 4.5 ns under a 372-nm UV excitation source,thus elucidating the potential of this layer as a fast colour-converting layer.A high data rate of up to 34 Mbps in solar-blind communication was achieved using the hybrid CsPbBr_(3)-silicon photodetection scheme in conjunction with a 278-nm UVC light-emitting diode(LED).These findings demonstrate the feasibility of an integrated high-speed photoreceiver design of a composition-tuneable perovskite-based phosphor and a low-cost silicon-based photodetector for UV communication.
基金the "National Science Council",Taiwan,for financial support (NSC 101-2811-M-194-008 for JPM)
文摘The use of a biodegradable natural plant-based surfactant extracted from soapberry is proposed for the remediation of Ni, Cr and Mn from industrial soil site in Hai-Pu, Taiwan. Batch experiments were performed under variation of fundamental factors （saponin concentration, pH, and incubation time） for metal remediation. Removal of Ni and Mn were increased with increasing saponin concentration （0.015-0.150 g/L）, whereas the removal of Cr was increased upto 0.075 g/L saponin. The Ni, Cr and Mn were removed significantly （p 〈 0.05） at near to the neutral and slightly acidic （pH 5 to 8） conditions. Removal efficiency of Ni （99%） from the soil was found to be greater than that of Cr （73%） or Mn （25%） in the presence of saponin at a concentration of 0.150 g/L at pH 5. The removal percentage increased with incubation time where the removal of Ni was faster than that of Cr and Mn. The result indicates the feasibility of cco-friendly removal of heavy metal （Ni, Cr and Mn） from industrial soil by soil washing process in presence of plant derived saponin.
文摘Grain growth kinetics of austenite in a hypoeutectoid steel（containing carbon of 0.35%）at 920 ℃ and in a hypereutectoid steel（containing carbon of 1%）at 980 ℃ for holding time ranging from 1 h to 6 h was investigated.The hypoeutectoid steel exhibited normal grain growth without solute drag hindrance with a time exponent（0.51）close to the theoretical value（0.5）.However,the grain growth of austenite in the hypereutectoid steel held up to 3 h was extremely slow,characterizing by a low value of time exponent（0.08）.Thereafter,a breakaway occurred and the grain growth in the hypereutectoid steel held from 3 h to 6 h progressed normally with a time exponent（0.52）close to the theoretical value（0.5）.
文摘Confocal laser endomicroscopy(CLE)is a novel endoscopic modality that provides real-time histological information via high-resolution magnified view of the mucosa.CLE has a higher sensitivity,specificity,and diagnostic accuracy in detecting atrophic gastritis as compared to chromoendoscopy and narrow-band imaging.It can even predict low-grade and high-grade intraepithelial neoplasia by analyzing gastric pit patterns.CLE may have some advantages over the standard biopsy protocol,such as higher diagnostic yield and fewer biopsy requirements.Its diagnostic accuracy in detecting superficial gastric cancer is higher than that of white-light endoscopy.Inherent limitations,such as a narrow field of vision,can be surpassed by technological advancements and integration with other detection methods.Artificial intelligence holds promise in automated analysis of histopathological images.Thus,CLE can be helpful in screening for early gastric cancer and may help reduce the risk of complications from repeated biopsies,such as mucosal damage,bleeding,and infection.
基金the University Grants Commission,New Delhi,India,for providing financial support in the form of the Junior Research Fellowship。
文摘Rapid urbanization creates complexity,results in dynamic changes in land and environment,and influences the land surface temperature(LST)in fast-developing cities.In this study,we examined the impact of land use/land cover(LULC)changes on LST and determined the intensity of urban heat island(UHI)in New Town Kolkata(a smart city),eastern India,from 1991 to 2021 at 10-a intervals using various series of Landsat multi-spectral and thermal bands.This study used the maximum likelihood algorithm for image classification and other methods like the correlation analysis and hotspot analysis(Getis–Ord Gi^(*) method)to examine the impact of LULC changes on urban thermal environment.This study noticed that the area percentage of built-up land increased rapidly from 21.91%to 45.63%during 1991–2021,with a maximum positive change in built-up land and a maximum negative change in sparse vegetation.The mean temperature significantly increased during the study period(1991–2021),from 16.31℃to 22.48℃in winter,29.18℃to 34.61℃in summer,and 19.18℃to 27.11℃in autumn.The result showed that impervious surfaces contribute to higher LST,whereas vegetation helps decrease it.Poor ecological status has been found in built-up land,and excellent ecological status has been found in vegetation and water body.The hot spot and cold spot areas shifted their locations every decade due to random LULC changes.Even after New Town Kolkata became a smart city,high LST has been observed.Overall,this study indicated that urbanization and changes in LULC patterns can influence the urban thermal environment,and appropriate planning is needed to reduce LST.This study can help policy-makers create sustainable smart cities.
基金support from diverse funding sources,including the National Key Program for S&T Research and Development of the Ministry of Science and Technology(MOST),Yifang Wang's Science Studio of the Ten Thousand Talents Project,the CAS Key Foreign Cooperation Grant,the National Natural Science Foundation of China(NSFC)Beijing Municipal Science&Technology Commission,the CAS Focused Science Grant,the IHEP Innovation Grant,the CAS Lead Special Training Programthe CAS Center for Excellence in Particle Physics,the CAS International Partnership Program,and the CAS/SAFEA International Partnership Program for Creative Research Teams.
文摘The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.
基金Supported by the DST Nano-mission,Govt of India,Grant No DST No.SR/NM/NS-1067/2016Facilities were provided by the West Bengal University of Animal&Fishery Sciences and CSIR-IICB for conducting this research。
文摘AIM:To evaluate if topical use ofαB-crystallin minipeptides supports corneal healing following flap surgery.METHODS:Cultured corneal cells were treated with fluorescent taggedαB-crystallin mini-peptides to assess its internalization.Cultured corneal cells pre-treated with or without the mini-peptides were exposed to H2O2 and cell viability was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.Elongation of neurites of cultured trigeminal neurones was examined following treatment either withαB-crystallin mini-peptides or protein.Cultured trigeminal neurones were pre-treated either withαB-crystallin mini-peptides or crystallin protein and exposed to H2O2 and presence of beading in the dendrites and axons was assessed.Corneal flap surgery was conducted on rabbit cornea and treated topically either withαB-crystallin peptide(0.5 mg/mL thrice daily for 14d)or phosphate-buffered saline(PBS).Corneal healing was evaluated under slit-lamp biomicroscope,mRNA expression of inflammatory cytokines were assessed and the corneas were evaluated by histopathology.RESULTS:Internalization ofαB-crystallin mini-peptides was ascertained by the detection of fluorescence within the corneal cells.The MTT assay revealed that treatment withαB-crystallin mini-peptide reduced cell death induced by H2O2 treatment.The mini-peptides did not influence the elongation of trigeminal neurites,but significantly(P<0.05)reduced beading in the neurites.In rabbit eye,the treated corneas showed reduced hyper-reflective zones(P<0.05)and suppression in the expression of inflammatory cytokines.Histopathological examination also revealed reduction of inflammatory response in treated corneas.CONCLUSION:TheαB-crystallin mini-peptides restrict the damage to corneal cells and neurons and aids in corneal healing.
文摘Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)is a common medical emergency in clinical practice.While the incidence has significantly reduced,the mortality rates have not undergone a similar reduction in the last few decades,thus presenting a significant challenge.This editorial outlines the key causes and risk factors of ANVUGIB and explores the current standards and recent updates in risk assessment scoring systems for predicting mortality and endoscopic treatments for achieving hemostasis.Since ANUVGIB predominantly affects the elderly population,the impact of comorbidities may be responsible for the poor outcomes.A thorough drug history is important due to the increasing use of antiplatelet agents and anticoagulants in the elderly.Early risk stratification plays a crucial role in deciding the line of management and predicting mortality.Emerging scoring systems such as the ABC(age,blood tests,co-morbidities)score show promise in predicting mortality and guiding clinical decisions.While conventional endoscopic therapies remain cornerstone approaches,novel techniques like hemostatic powders and over-the-scope clips offer promising alternatives,particularly in cases refractory to traditional modalities.By integrating validated scoring systems and leveraging novel therapeutic modalities,clinicians can enhance patient care and mitigate the substantial morbidity and mortality associated with ANVUGIB.
文摘BACKGROUND There are indications that viral myocarditis,demand ischemia,and renin-angio-tensin-aldosterone system pathway activation play essential roles in troponin elevation in coronavirus disease 2019(COVID-19)patients.Antiviral medications and steroids are used to treat viral myocarditis,but their effect in patients with elevated troponin,possibly from myocarditis,has not been studied.AIM To evaluate the effect of dexamethasone,remdesivir,and angiotensin-converting enzyme(ACE)inhibitors(ACEI)on mortality in COVID-19 patients with elevated troponin.METHODS Our retrospective observational study involved 1788 COVID-19 patients at seven hospitals in Southern California,United States.We did a backward selection Cox multivariate regression analysis to determine predictors of mortality in our study population.Additionally,we did a Kaplan Meier survival analysis in the subset of patients with elevated troponin,comparing survival in patients that received dexamethasone,remdesivir,and ACEI with those that did not.RESULTS The mean age was 66 years(range 20-110),troponin elevation was noted in 11.5%of the patients,and 29.9%expired.The patients'age[hazard ratio(HR)=1.02,P<0.001],intensive care unit admission(HR=5.07,P<0.001),and ventilator use(HR=0.68,P=0.02)were significantly associated with mortality.In the subset of patients with elevated troponin,there was no statistically significant difference in survival in those that received remdesivir(0.07),dexamethasone(P=0.63),or ACEI(P=0.8)and those that did not.CONCLUSION Although elevated troponin in COVID-19 patients has been associated with viral myocarditis and ACE II receptors,conventional viral myocarditis treatment,including antiviral and steroids,and ACEI did not show any effect on mortality in these patients.
基金Council for Scientific and Industrial Research (CSIR),New Delhi for providing the fellowshipthe Defence Institute of Physiology & Allied Sciences (DIPAS),the Defence Research & Development Organisation (DRDO),Government of India,for their consecutive financial support
文摘Present study deals with the straight impact of hypobaric hypoxia on the quantity and composition of some predominant fecal microflora and its functional aspects. For that, isolated fecal contents of rat were exposed to two different simulated air pressures （70 kPa and 40 kPa） for different time durations （1, 3, and 5 h） and the bacterial community composition was compared with normobaric groups （101.3 kPa）. It was found that the total anaerobes, Escherichio coli, Enterbocters spp., Bi^idobocterium spp., CIostridium spp. were increased whereas total aerobes were decreased at both hypobaric treatments. The increased number of amplicon was detected in the pressure-treated groups than the control that clearly mentioned the disruption of microbiota structure at different simulated hypobaric-hypoxia. The amylase, protease, tannase, 13-glucuronidase, and alkaline phosphatase activities were increased at these atmospheric pressures. Thus, the present investigation demonstrates that the hypobaric hypoxia is an important environmental factor which can strongly modulate the composition of intestinal flora as well as microfiora-derived functional aspects.
文摘An investigation was carried out to modify the toughness of triethylene tetramine cured DGEBA （diglycidyl ether of bisphenol-A） resin using solid amine terminated poly （ethylene glycol） benzoate （ATPEGB） as modifier with and without red mud waste particles. The solid ATPEGB modifier synthesized from the acid catalyzed esterification reaction of poly （ethylene glycol） （PEG） and 4-amino benzoic acid was characterized by Fourier transform infrared spectroscopy （FT-IR） and ^1H-NMR （nuclear magnetic resonance） spectroscopies, viscosity measurements, and solubility parameter calculation. The unfilled and red mud waste filled modified epoxy networks were evaluated with impact, adhesive, tensile, flexural and thermal properties by differential scanning calorimetry （DSC）, thermogravimetric （TG） and dynamic mechanical analysis （DMA）. The effect of modifier concentration and red mud waste particles on toughening behavior was also investigated. The optimum properties were obtained at 12.5 phr （parts per hundred parts of resin） concentration of the modifier. The ATPEGB modified cured epoxy was thermally stable up to 315℃. The morphology on fracture surfaces of cured epoxy was also analyzed by scanning electron microscopy （SEM）.
基金the financial support received from MHRD, India during the course of research work.
文摘The present work reviews different decision making tools(material comparing and choosing tools)used for selecting the best material considering different parameters.In this review work,the authors have tried to address the following important enquiries:1)the engineering applications addressed by the different material choosing and ranking methods;2)the predominantly used decision making tools addressing the optimal material selection for the engineering applications;3)merits and demerits of decision making tools used;4)the dominantly used criteria or objectives considered while selecting a suitable alternative material;5)overview of DEA on material selection field.The authors have surveyed literatures from different regions of the globe and considered literatures since 1988.The present review not only stresses the importance of material selection in the early design stage of the product development but also aids the design and material engineers to apply different decision making tools systematically.
文摘In this study, a newly developed titanium superalloy, i.e., the Ti-5553 alloy has used for hot machining. This material replaced Ti-grade-5 alloy in the application of aerospace, automobile, and biomedical sector. However, similar to Ti-grade-5 alloy, the Ti-5553 alloy has a low thermal conductivity which makes it difficult-to-cut material categories hence, high tool wear, cutting force and bad surface finish. Hot machining of Ti-5553 has been studied at different machining condition (room and hot) using Deform-2D finite element analysis. The result from the simulation test was compared with the experimental value and reduction of cutting and thrust forces was observed. The experiment was carried out with the same input parameters as simulation, and good coherence between them observed. Additionally, cutting zone temperature, effective stress, etc. for both room and elevated the temperature are also discussed.
基金supported by the following funding sources:Science Committee of the Republic of Armenia Grant No.18T-1C180Australian Research Council and research grant Nos.DP180102629,DP170102389,DP170102204,DP150103061,FT130100303,and FT130100018+22 种基金Austrian Federal Ministry of Education,Science and Research,and Austrian Science Fund No.P 31361-N36Natural Sciences and Engineering Research Council of Canada,Compute Canada and CANARIEChinese Academy of Sciences and research grant No.QYZDJ-SSW-SLH011National Natural Science Foundation of China and research grant Nos.11521505,11575017,11675166,11761141009,11705209,and 11975076LiaoNing Revitalization Talents Program under contract No.XLYC1807135Shanghai Municipal Science and Technology Committee under contract No.19ZR1403000Shanghai Pujiang Program under Grant No.18PJ1401000the CAS Center for Excellence in Particle Physics(CCEPP)the Ministry of Education,Youth and Sports of the Czech Republic under Contract No.LTT17020Charles University grants SVV260448 and GAUK 404316European Research Council,7th Framework PIEF-GA-2013-622527Horizon 2020 Marie Sklodowska-Curie grant agreement No.700525’NIOBE,’Horizon 2020 Marie Sklodowska-Curie RISE project JENNIFER grant agreement No.644294Horizon 2020 ERC-Advanced Grant No.267104NewAve No.638528(European grants)L’Institut National de Physique Nucléaire et de Physique des Particules(IN2P3)du CNRS(France),BMBF,DFG,HGF,MPG and AvH Foundation(Germany)Department of Atomic Energy and Department of Science and Technology(India)Israel Science Foundation grant No.2476/17United States-Israel Binational Science Foundation grant No.2016113Istituto Nazionale di Fisica Nucleare and the research grants BELLE2Japan Society for the Promotion of Science,Grant-in-Aid for Scientific Research grant Nos.16H03968,16H03993,16H06492,16K05323,17H01133,17H05405,18K03621,18H03710,18H05226,19H00682,26220706,and 26400255the National Institute of Informatics,and Science Information NETwork 5(SINET5)the Ministry of Education,Culture,Sports,Science,an
文摘From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.
文摘Cooperation in spectral sensing （SS） offers a fast and reliable detection of primary user （PU） transmission over a frequency spectrum at the expense of increased energy consumption. Since the fusion center （FC） has to handle a large set of data, a duster based approach, specifically fuzzy c-means clustering （FCM）, has been extensively used in energy detection based cooperative spectrum sensing （CSS）. However, the performance of FCM degrades at low signal-to-noise ratios （SNR） and in the presence of multiple PUs as energy data patterns at the FC are often found to be non-spherical i.e. overlapping. To address the problem, this work explores the scope of kernel fuzzy c-means （KFCM） on energy detection based CSS through the projection of non-linear input data to a high dimensional feature space. Extensive simulation results are shown to highlight the improved detection of multiple PUs at low SNR with low energy consumption. An improvement in the detection probability by ～6.78% and ～6.96% at -15 dBW and -20 dBW, respectively, is achieved over the existing FCM method.
基金We thank the Director,CSIR-Central Institute of Mining and Fuel Research,Dhanbad for permission to publish this paper.We also thank our colleagues at the Resource Quality Assessment and CTL Research Group for their support.
文摘Four coal samples from Jharia basin,India are treated with nitric acid in glacial acetic acid and aqueous media to find out the chemical,petrographic and spatial structure of the organic mass by X-ray diffraction(XRD)and Fourier Transform Infrared Spectroscopy(FTIR)techniques.X-ray parameters of coal like interlayer spacing(d_(002)),crystallite size(L_(c)),aroamticity(f_(a)),average number of aromatic layers(N_(c)),and coal rank(I_(26)/I_(20))have been determined using profilefitting software.Considerable variation is observed in treated coals in comparison to the demineralized coals.The d_(002)values of treated coals have increased in both the media showing increase in disordering of organic moieties.A linear relationship has been observed between d_(002)values with the volatile matter of the coals.Similarly,the d_(002)values show linear relationship with C_(dmf) contents for demineralized as well as for the treated coals in both the media.The L_(c) and N_(c) values have decreased in treated coals corresponding to demineralized coals.The present study shows that nitration in both the media is capable of removing the aliphatic side chains from the coals and aromaticity(f_(a))increases with increase in rank and shows a linear relationship with the vitrinite reflectance.The corresponding I_(26)/I_(20)values are least for treated coals in glacial acetic acid medium followed by raw and then to treated coals in aqueous medium.FTIR studies show that coal arenes of the raw coals are converted into nitro-arenes in structurally modified coals(SMCs)in both the media,the corresponding bands at 1550-1490 and 1355-1315 cm^(-1) respectively.FTIR study confirms that nitration is the predominant phenomenon,though,oxidation and nitration phenomena takes place simultaneously during treatment with nitric acid to form SMCs.In comparison to raw coals,the SMCs show higher aromaticity and may be easily converted to coal derived products like activated carbon and specialty carbon materials.
文摘In this paper, we consider three species harvesting model and develop a solution proce- dure which is able to calculate the equilibrium points of the model where some biological parameters of the model are interval numbers. A parametric mathematical program is formulated to find the biological equilibrium of the model for different values of parame- ters. This interval-valued problem is converted into equivalent crisp model using interval operations. The main advantage of the proposed procedure is that we can present dif- ferent characteristics of the model in a single framework. Analytically, the existence of steady state and stabilities are looked into. Using mathematical software, the model is illustrated and the results are obtained and presented in tabular and graphical forms.
基金University Grant commission(UGC),New Delhi,India,for providing financial assistance
文摘Objective:To investigate hepatoprotective activity of ethanol extract of Melothria heterophyila Lour Cogn.（EEMH） against CCl<sub>4</sub>-induced hepatic damage in rats.Methods:β-sitosterol was isolated by column chromatography and characterized spectroscopically.Two different doses（200 and 400 mg/kg bw） of EEMH were administered orally in alternate days.The hepatoprotective activity was studied in liver by measuring biochemical parameters such as serum aspartate amino transferase（AST）,alanine amino transferase（ALT）,alkaline phosphatase（ALP）,total protein and total bilirubin.Lipid peroxidation product and different antioxidant enzyme activities were assessed in liver homogenate.Results:EEMH reduced all biochemical parameters and lipid peroxidation,as well as it increased the antioxidant enzyme activities in comparison with silymarin.The protective effect of the extract on CCl<sub>4</sub> induced damage was confirmed by histopathological examination of the liver.Conclusions:This result strongly supports the protective effect of EEMH against acute liver injury,and may be attributed to its antioxidative activity.
