Multifunctional and diversified agriculture can address diverging pressures and demands by simultaneously enhancing productivity,biodiversity,and the provision of ecosystem services.The use of digital technologies can...Multifunctional and diversified agriculture can address diverging pressures and demands by simultaneously enhancing productivity,biodiversity,and the provision of ecosystem services.The use of digital technologies can support this by designing and managing resource-efficient and context-specific agricultural systems.We present the Digital Agricultural Knowledge and Information System(DAKIS)to demonstrate an approach that employs digital technologies to enable decision-making towards diversified and sustainable agriculture.To develop the DAKIS,we specified,together with stakeholders,requirements for a knowledge-based decision-support tool and reviewed the literature to identify limitations in the current generation of tools.The results of the review point towards recurring challenges regarding the consideration of ecosystem services and biodiversity,the capacity to foster communication and cooperation between farmers and other actors,and the ability to link multiple spatiotemporal scales and sustainability levels.To overcome these challenges,the DAKIS provides a digital platform to support farmers'decision-making on land use and management via an integrative spatiotemporally explicit approach that analyses a wide range of data from various sources.The approach integrates remote and in situ sensors,artificial intelligence,modelling,stakeholder-stated demand for biodiversity and ecosystem services,and participatory sustainability impact assessment to address the diverse drivers affecting agricultural land use and management design,including natural and agronomic factors,economic and policy considerations,and socio-cultural preferences and settings.Ultimately,the DAKIS embeds the consideration of ecosystem services,biodiversity,and sustainability into farmers'decision-making and enables learning and progress towards site-adapted small-scale multifunctional and diversified agriculture while simultaneously supporting farmers'objectives and societal demands.展开更多
We report the realization of a synthetic magnetic field for photons and polaritons in a honeycomb lattice of coupled semiconductor micropillars.A strong synthetic field is induced in both the s and p orbital bands by ...We report the realization of a synthetic magnetic field for photons and polaritons in a honeycomb lattice of coupled semiconductor micropillars.A strong synthetic field is induced in both the s and p orbital bands by engineering a uniaxial hopping gradient in the lattice,giving rise to the formation of Landau levels at the Dirac points.We provide direct evidence of the sublattice symmetry breaking of the lowest-order Landau level wavefunction,a distinctive feature of synthetic magnetic fields.Our realization implements helical edge states in the gap between n=0 and n=±1 Landau levels,experimentally demonstrating a novel way of engineering propagating edge states in photonic lattices.In light of recent advances in the enhancement of polariton–polariton nonlinearities,the Landau levels reported here are promising for the study of the interplay between pseudomagnetism and interactions in a photonic system.展开更多
Although Caribbean mixed-species herbivorous fish groups are an important component to the reef community by helping to crop algae that often overgrow and kill corals, little is known of how they organize their foragi...Although Caribbean mixed-species herbivorous fish groups are an important component to the reef community by helping to crop algae that often overgrow and kill corals, little is known of how they organize their foraging groups. In spite of a highly flexible membership, the basic structure of these groups consists of a “core species,” that leads the group and often is either the striped parrotfish <i>(Scarus iserti)</i> or the ocean surgeon <i>(Acanthurus tractus)</i>. These species lead their groups to open areas where they feed largely on low profile turf algae. Other members prefer macro algae and are termed “associate species,” of which the two common species we studied were the stoplight parrotfish <i>(Sparisoma viride)</i> and the redband parrotfish <i>(Sparisoma aurofrenatum)</i>. In spite of the large difference in group sizes between Jamaica and Grand Cayman Islands, the relationships between movement patterns and compositional changes were largely consistent. There was no support for the hypothesis that these dramatic and continuous group changes were related to foraging success. Instead, we speculated that these group changes perhaps were designed to maintain cohesion among a membership that was spread over a wide area. We also examined if associates species may be more than just passive followers of core species but rather instigated the attracting or the building of core groups. Both associate species do attract striped parrotfish in open areas and thus appear active in initiating mixed-species groups. Finally, given that associate species seem to derive little foraging benefit from following core species, we tested the hypothesis that associate species joined core groups to gain protection against predators. Associate species do not selectively join the larger groups of striped parrotfish but appear to join core species randomly and the groups they joined resembled the wide assortment of core groups available in the area. Thus, while associates may be joining core groups for protection, this 展开更多
Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and ...Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and progressive fibrosis of different structures, including the heart valves, the myocardium and the pericardium, the coronary arteries and the conduction system. As new therapies have improved survival, many patients with cancer (mostly Hodgkin’s disease and breast cancer) are now at risk of cardiovascular (CV) complications following radiation therapy. Objectives: To raise awareness of CV complications following chest irradiation. Method: We present 5 patients that we treated during a short period of time (between June 2013 (6/2013) and February 2015 (2/2016)), who suffered CV involvement that needed therapy, following chest irradiation. Conclusions: Patients after chest irradiation should be followed periodically, in order to diagnose and treat CV complications, in time.展开更多
Fractures of the talus are rare in children.A high index of suspicion is needed to avoid missing such an injury,which is not an uncommon occurrence especially with undisplaced fractures.We present an unusual case of a...Fractures of the talus are rare in children.A high index of suspicion is needed to avoid missing such an injury,which is not an uncommon occurrence especially with undisplaced fractures.We present an unusual case of an undisplaced talar neck fracture in a five-year-old child leading to a delayed presentation of a symptomatic osteochondral loose body in the ankle joint.To our knowledge there are no reports in the literature of osteochondral loose bodies occurring in conjunction with an associated undisplaced talar neck fracture in either children or adults.The loose body was removed using anterior ankle arthroscopy.The child had an uneventful post operative recovery and regained full range of movement and function of his ankle joint and was discharged at one year follow-up.We aim to highlight the need to have a low threshold to further evaluate symptomatic children after fracture healing of an undisplaced talar neck fracture for a possible associated loose bodyin the ankle joint.展开更多
The Merkel cell-neurite complex initiates the perception of touch and mediates Ap slowly adapting type I responses. Lichen planus is a chronic inflammatory autoimmune disease with T-cell-mediated inflammation, whereas...The Merkel cell-neurite complex initiates the perception of touch and mediates Ap slowly adapting type I responses. Lichen planus is a chronic inflammatory autoimmune disease with T-cell-mediated inflammation, whereas hyperkeratosis is characterized with or without epithelial dysplasia in the oral mucosa. To determine the effects of lichen planus and hyperkeratosis on the Merkel cell-neurite complex, healthy oral mucosal epithelium and lesional oral mucosal epithelium of lichen planus and hyperkeratosis patients were stained by immunohistochemistry （the avidin-biotin-peroxidase complex and double immunofluorescence methods）using pan cytokeratin, cytokeratin 20 （K20, a Merkel cell marker）, and neurofilament 200 （NF200, a myelinated Aβ- and Aδ-nerve fibre marker） antibodies. N F200-immunoreactive （ir） nerve fibres in healthy tissues and in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis were counted and statistically analysed. In the healthy oral mucosa, K20-positive Merkel cells with and without close association to the intraepithelial NF200-ir nerve fibres were detected. In the lesional oral mucosa of lichen planus and hyperkeratosis patients, extremely rare NF200-ir nerve fibres were detected only in the lamina propria. Compared with healthy tissues, lichen planus and hyperkeratosis tissues had significantly decreased numbers of NF200-ir nerve fibres in the oral mucosal epithelium. Lichen planus and hyperkeratosis were associated with the absence of Aβ-nerve endings in the oral mucosal epithelium. Thus, we conclude that mechanosensation mediated by the Merkel cell-neurite complex in the oral mucosal epithelium is impaired in lichen planus and hvperkeratosis.展开更多
This paper presents a generic mathematical model for depicting the diffusion of an innovative product on a given market. Our approach relies on a probabilistic modeling of each customer behavior with respect to the co...This paper presents a generic mathematical model for depicting the diffusion of an innovative product on a given market. Our approach relies on a probabilistic modeling of each customer behavior with respect to the commercial process which is used to promote such a product. We introduce in particular the concept of coherent market that corresponds to a market which can be analyzed in a uniform way within our model. This last notion allows us to recover the classical empirical results that were discovered and widely studied by E.M. Rogers and his school. We explain finally how to use our approach as a support for analytic predictive marketing.展开更多
The decline in herbivorous fishes is an important contributing factor to the degradation of coral reefs, because their reduction contributes to macro algae overgrowth, which can have harmful effects on corals. Herbivo...The decline in herbivorous fishes is an important contributing factor to the degradation of coral reefs, because their reduction contributes to macro algae overgrowth, which can have harmful effects on corals. Herbivorous fish often form mixed-species groups to locate foraging sites and for defense. The movements and compositions of these groups are dependent on the relative numbers of different species present. Some species, such as the striped parrotfish (Scarus iserti) and ocean surgeonfish (Acanthurus bahianus), serve as core species that lead mixed-species groups. Others, such as the redband (Sparisoma aurofrenatum) and stoplight parrotfishes (Sparisoma viride), follow core species as their associates. Despite the potential importance and abundance of mixed-species groups on reefs, little attention has been given to their composition and movements. Our intent was to determine whether the social dynamics of mixed-species groups in Jamaica were similar to those of Grand Cayman. The overall sizes of mixed-species groups were smaller in Grand Cayman. Focal striped parrotfish in Grand Cayman formed smaller groups, changed composition less, and moved less frequently than in Jamaica. Although probably more abundant than striped parrotfish, the ocean surgeonfish in Grand Cayman did not function as a core species but rather attached themselves as associates to the smaller striped parrotfish groups. Redband parrotfish moved less often in Grand Cayman, and appeared to be more dependent on striped parrotfish groups than stoplight parrotfish. While previous studies on herbivorous reef fish have shown that changes in foraging patterns can change with location, perhaps related to structural heterogeneity and resource distribution, this study illustrates that social interactions between common members of mixed-species groups also change. We suggest that the intra and interspecific social interactions in Grand Cayman are less attuned to finding erratically located high quality resources than those in Jamaica. Other plausible展开更多
To validate the accuracy and consistency of respiratory inductive plethysmography (RIP) in measuring tidal volume after an overnight sleep, tidal volumes of 18 patients with suspected sleep disordered breathing and 8...To validate the accuracy and consistency of respiratory inductive plethysmography (RIP) in measuring tidal volume after an overnight sleep, tidal volumes of 18 patients with suspected sleep disordered breathing and 8 normal volunteers were measured simultaneously with RIP (V TRIP ) and with an ultrasonic airflow meter (V TUFM ) before and after an unstrained overnight sleep on supine and lateral decubitus. The bias of the V TRIP was expressed as (V TRIP V TUFM )/ V TUFM ·100 %, limits of agreement between V TRIP and V TUFM was measured by averaged bias ±2 s . Results showed that in normal subjects, the bias of RIP before and after overnight sleep was precise and consistent in both supine (0.7 % and -1.6 %) and lateral decubitus (3.7 % and -0.56 %). In these patients, the bias of RIP before and after sleep in supine also remained small (1.9 % and 1.7 %), but it became larger in lateral decubitus (24.5 % and 20.4 %) and 11.5 % exceeded the limits of agreement observed in the evening. The patients′ body mass indices (BMI) were higher than those of normal subjects (median 34.2 vs. 27.8 kg/m 2). Pooled data showed that the bias of V TRIP in the morning on lateral decubitus but not on supine was correlated to BMI (Spearman R=0.32, n =52, P =0.02). Thus, we were led to conclude that the accuracy of V TRIP overnight was precise and consistent in normal subjects, but the deviation of V TRIP measured on lateral decubitus in patients especially in those with excessive obesity was greater, thus, the method should not be used for quantitative determination.展开更多
Traumatic thoracic aortic injury remains a major cause of death following motor vehicle accidents.Endovascular approaches have begun to supersede open repair,offering the hope of reduced morbidity and mortality.The av...Traumatic thoracic aortic injury remains a major cause of death following motor vehicle accidents.Endovascular approaches have begun to supersede open repair,offering the hope of reduced morbidity and mortality.The available endovascular technology is associated with specific anatomic considerations and complications.This paper will review the current status of endovascular management of traumatic thoracic aortic injuries.展开更多
基金This work was made possible through funding from the Digital Agriculture Knowledge and Information System(DAKIS)Project(ID:FKZ 031B0729A)financed by the German Federal Ministry of Education and Research(BMBF).Sincere thanks to Amir Armaghan for his amazing sketches on the DAKIS GUI,enabling us to approach the work from the user's perspective.We acknowledge the valuable contributions of Stefan Zachaeus,Sebastian Möller and Nils Niemann on the design of the DAKIS back end.We thank the many other members of the DAKIS crew that one way or another contribute expertise and input to the development of the DAKIS.
文摘Multifunctional and diversified agriculture can address diverging pressures and demands by simultaneously enhancing productivity,biodiversity,and the provision of ecosystem services.The use of digital technologies can support this by designing and managing resource-efficient and context-specific agricultural systems.We present the Digital Agricultural Knowledge and Information System(DAKIS)to demonstrate an approach that employs digital technologies to enable decision-making towards diversified and sustainable agriculture.To develop the DAKIS,we specified,together with stakeholders,requirements for a knowledge-based decision-support tool and reviewed the literature to identify limitations in the current generation of tools.The results of the review point towards recurring challenges regarding the consideration of ecosystem services and biodiversity,the capacity to foster communication and cooperation between farmers and other actors,and the ability to link multiple spatiotemporal scales and sustainability levels.To overcome these challenges,the DAKIS provides a digital platform to support farmers'decision-making on land use and management via an integrative spatiotemporally explicit approach that analyses a wide range of data from various sources.The approach integrates remote and in situ sensors,artificial intelligence,modelling,stakeholder-stated demand for biodiversity and ecosystem services,and participatory sustainability impact assessment to address the diverse drivers affecting agricultural land use and management design,including natural and agronomic factors,economic and policy considerations,and socio-cultural preferences and settings.Ultimately,the DAKIS embeds the consideration of ecosystem services,biodiversity,and sustainability into farmers'decision-making and enables learning and progress towards site-adapted small-scale multifunctional and diversified agriculture while simultaneously supporting farmers'objectives and societal demands.
基金supported by the ERC grant Honeypol,the H2020-FETFLAG project PhoQus(820392)the QUANTERA project Interpol(ANR-QUAN-0003-05)+11 种基金the French National Research Agency project Quantum Fluids of Light(ANR-16-CE30-0021)the French government through the Programme Investissement d’Avenir(I-SITE ULNE/ANR-16-IDEX-0004 ULNE)managed by the Agence Nationale de la Recherchethe French RENATECH network,the Labex CEMPI(ANR-11-LABX-0007)the CPER Photonics for Society P4S and the Metropole Europeenne de Lille(MEL)via the project TFlightfinancial support from the FPI Scholarship No.BES-2015-074708the Spanish MINECO grant No.MAT2017-83722-Rsupported by funding from the ERC Starting Grant TopoColdsupported by JSPS KAKENHI Grant Number JP18H05857JST PRESTO Grant Number JPMJPR19L2JST CREST Grant Number JPMJCR19T1the RIKEN Incentive Research Projectthe Interdisciplinary Theoretical and Mathematical Sciences Program(iTHEMS)at RIKEN.
文摘We report the realization of a synthetic magnetic field for photons and polaritons in a honeycomb lattice of coupled semiconductor micropillars.A strong synthetic field is induced in both the s and p orbital bands by engineering a uniaxial hopping gradient in the lattice,giving rise to the formation of Landau levels at the Dirac points.We provide direct evidence of the sublattice symmetry breaking of the lowest-order Landau level wavefunction,a distinctive feature of synthetic magnetic fields.Our realization implements helical edge states in the gap between n=0 and n=±1 Landau levels,experimentally demonstrating a novel way of engineering propagating edge states in photonic lattices.In light of recent advances in the enhancement of polariton–polariton nonlinearities,the Landau levels reported here are promising for the study of the interplay between pseudomagnetism and interactions in a photonic system.
文摘Although Caribbean mixed-species herbivorous fish groups are an important component to the reef community by helping to crop algae that often overgrow and kill corals, little is known of how they organize their foraging groups. In spite of a highly flexible membership, the basic structure of these groups consists of a “core species,” that leads the group and often is either the striped parrotfish <i>(Scarus iserti)</i> or the ocean surgeon <i>(Acanthurus tractus)</i>. These species lead their groups to open areas where they feed largely on low profile turf algae. Other members prefer macro algae and are termed “associate species,” of which the two common species we studied were the stoplight parrotfish <i>(Sparisoma viride)</i> and the redband parrotfish <i>(Sparisoma aurofrenatum)</i>. In spite of the large difference in group sizes between Jamaica and Grand Cayman Islands, the relationships between movement patterns and compositional changes were largely consistent. There was no support for the hypothesis that these dramatic and continuous group changes were related to foraging success. Instead, we speculated that these group changes perhaps were designed to maintain cohesion among a membership that was spread over a wide area. We also examined if associates species may be more than just passive followers of core species but rather instigated the attracting or the building of core groups. Both associate species do attract striped parrotfish in open areas and thus appear active in initiating mixed-species groups. Finally, given that associate species seem to derive little foraging benefit from following core species, we tested the hypothesis that associate species joined core groups to gain protection against predators. Associate species do not selectively join the larger groups of striped parrotfish but appear to join core species randomly and the groups they joined resembled the wide assortment of core groups available in the area. Thus, while associates may be joining core groups for protection, this
文摘Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and progressive fibrosis of different structures, including the heart valves, the myocardium and the pericardium, the coronary arteries and the conduction system. As new therapies have improved survival, many patients with cancer (mostly Hodgkin’s disease and breast cancer) are now at risk of cardiovascular (CV) complications following radiation therapy. Objectives: To raise awareness of CV complications following chest irradiation. Method: We present 5 patients that we treated during a short period of time (between June 2013 (6/2013) and February 2015 (2/2016)), who suffered CV involvement that needed therapy, following chest irradiation. Conclusions: Patients after chest irradiation should be followed periodically, in order to diagnose and treat CV complications, in time.
文摘Fractures of the talus are rare in children.A high index of suspicion is needed to avoid missing such an injury,which is not an uncommon occurrence especially with undisplaced fractures.We present an unusual case of an undisplaced talar neck fracture in a five-year-old child leading to a delayed presentation of a symptomatic osteochondral loose body in the ankle joint.To our knowledge there are no reports in the literature of osteochondral loose bodies occurring in conjunction with an associated undisplaced talar neck fracture in either children or adults.The loose body was removed using anterior ankle arthroscopy.The child had an uneventful post operative recovery and regained full range of movement and function of his ankle joint and was discharged at one year follow-up.We aim to highlight the need to have a low threshold to further evaluate symptomatic children after fracture healing of an undisplaced talar neck fracture for a possible associated loose bodyin the ankle joint.
文摘The Merkel cell-neurite complex initiates the perception of touch and mediates Ap slowly adapting type I responses. Lichen planus is a chronic inflammatory autoimmune disease with T-cell-mediated inflammation, whereas hyperkeratosis is characterized with or without epithelial dysplasia in the oral mucosa. To determine the effects of lichen planus and hyperkeratosis on the Merkel cell-neurite complex, healthy oral mucosal epithelium and lesional oral mucosal epithelium of lichen planus and hyperkeratosis patients were stained by immunohistochemistry （the avidin-biotin-peroxidase complex and double immunofluorescence methods）using pan cytokeratin, cytokeratin 20 （K20, a Merkel cell marker）, and neurofilament 200 （NF200, a myelinated Aβ- and Aδ-nerve fibre marker） antibodies. N F200-immunoreactive （ir） nerve fibres in healthy tissues and in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis were counted and statistically analysed. In the healthy oral mucosa, K20-positive Merkel cells with and without close association to the intraepithelial NF200-ir nerve fibres were detected. In the lesional oral mucosa of lichen planus and hyperkeratosis patients, extremely rare NF200-ir nerve fibres were detected only in the lamina propria. Compared with healthy tissues, lichen planus and hyperkeratosis tissues had significantly decreased numbers of NF200-ir nerve fibres in the oral mucosal epithelium. Lichen planus and hyperkeratosis were associated with the absence of Aβ-nerve endings in the oral mucosal epithelium. Thus, we conclude that mechanosensation mediated by the Merkel cell-neurite complex in the oral mucosal epithelium is impaired in lichen planus and hvperkeratosis.
基金This paper was supported by the Ecole Polytechnique and Thales chair "Engineering of Complex Systems".
文摘This paper presents a generic mathematical model for depicting the diffusion of an innovative product on a given market. Our approach relies on a probabilistic modeling of each customer behavior with respect to the commercial process which is used to promote such a product. We introduce in particular the concept of coherent market that corresponds to a market which can be analyzed in a uniform way within our model. This last notion allows us to recover the classical empirical results that were discovered and widely studied by E.M. Rogers and his school. We explain finally how to use our approach as a support for analytic predictive marketing.
文摘The decline in herbivorous fishes is an important contributing factor to the degradation of coral reefs, because their reduction contributes to macro algae overgrowth, which can have harmful effects on corals. Herbivorous fish often form mixed-species groups to locate foraging sites and for defense. The movements and compositions of these groups are dependent on the relative numbers of different species present. Some species, such as the striped parrotfish (Scarus iserti) and ocean surgeonfish (Acanthurus bahianus), serve as core species that lead mixed-species groups. Others, such as the redband (Sparisoma aurofrenatum) and stoplight parrotfishes (Sparisoma viride), follow core species as their associates. Despite the potential importance and abundance of mixed-species groups on reefs, little attention has been given to their composition and movements. Our intent was to determine whether the social dynamics of mixed-species groups in Jamaica were similar to those of Grand Cayman. The overall sizes of mixed-species groups were smaller in Grand Cayman. Focal striped parrotfish in Grand Cayman formed smaller groups, changed composition less, and moved less frequently than in Jamaica. Although probably more abundant than striped parrotfish, the ocean surgeonfish in Grand Cayman did not function as a core species but rather attached themselves as associates to the smaller striped parrotfish groups. Redband parrotfish moved less often in Grand Cayman, and appeared to be more dependent on striped parrotfish groups than stoplight parrotfish. While previous studies on herbivorous reef fish have shown that changes in foraging patterns can change with location, perhaps related to structural heterogeneity and resource distribution, this study illustrates that social interactions between common members of mixed-species groups also change. We suggest that the intra and interspecific social interactions in Grand Cayman are less attuned to finding erratically located high quality resources than those in Jamaica. Other plausible
文摘To validate the accuracy and consistency of respiratory inductive plethysmography (RIP) in measuring tidal volume after an overnight sleep, tidal volumes of 18 patients with suspected sleep disordered breathing and 8 normal volunteers were measured simultaneously with RIP (V TRIP ) and with an ultrasonic airflow meter (V TUFM ) before and after an unstrained overnight sleep on supine and lateral decubitus. The bias of the V TRIP was expressed as (V TRIP V TUFM )/ V TUFM ·100 %, limits of agreement between V TRIP and V TUFM was measured by averaged bias ±2 s . Results showed that in normal subjects, the bias of RIP before and after overnight sleep was precise and consistent in both supine (0.7 % and -1.6 %) and lateral decubitus (3.7 % and -0.56 %). In these patients, the bias of RIP before and after sleep in supine also remained small (1.9 % and 1.7 %), but it became larger in lateral decubitus (24.5 % and 20.4 %) and 11.5 % exceeded the limits of agreement observed in the evening. The patients′ body mass indices (BMI) were higher than those of normal subjects (median 34.2 vs. 27.8 kg/m 2). Pooled data showed that the bias of V TRIP in the morning on lateral decubitus but not on supine was correlated to BMI (Spearman R=0.32, n =52, P =0.02). Thus, we were led to conclude that the accuracy of V TRIP overnight was precise and consistent in normal subjects, but the deviation of V TRIP measured on lateral decubitus in patients especially in those with excessive obesity was greater, thus, the method should not be used for quantitative determination.
文摘Traumatic thoracic aortic injury remains a major cause of death following motor vehicle accidents.Endovascular approaches have begun to supersede open repair,offering the hope of reduced morbidity and mortality.The available endovascular technology is associated with specific anatomic considerations and complications.This paper will review the current status of endovascular management of traumatic thoracic aortic injuries.
