As part of the Dragon 4 project,the water extents of Wuchang and Shengjin lakes have been extracted from Sentinel-2 time series,using all exploitable images since the beginning of the acquisitions in 2015.The aim of t...As part of the Dragon 4 project,the water extents of Wuchang and Shengjin lakes have been extracted from Sentinel-2 time series,using all exploitable images since the beginning of the acquisitions in 2015.The aim of the study is to assess the capability of the Sentinel-2 constellation and Landsat 8 over the Anhui region,especially the high temporal resolution.A total of 32 dates have been used and 10 Landsat 8 images(Libra)have been added to try to reduce the temporal gaps in the Sentinel-2 acquisitions caused by cloudy conditions.Extractions were done using a SERTIT-ICube automatized routine based on a supervised Maximum Likelihood Classification.These extractions allow to recreate the dynamic of the two lakes and show the drought and wet periods.During the 3 years interval,the surface peaks in July 2016 for both lakes.The lowest level appears at two different dates for each lake;in January 2018 for Wuchang,in February 2017 for Shengjin.Wuchang Lake surface area appears to be more variable than Shengjin Lake,with many local maximum and minimum between the end of 2017 and April 2018.In the case of Wuchang Lake,floating vegetation is a problem for automatic water surface area extraction.The lake is covered by vegetation during long periods of time and the water below can’t be detected by automatic radiometric means.Nevertheless,Sentinel-2 stays a pertinent and powerful tool for hydrological monitoring of lakes confirming the expectation from the remote sensing wetland community before launch.The presence of NIR and SWIR bands induces a strong discrimination between water and other classes,and the systematic acquisitions create dense time series,making analysis more consistent.It makes possible to sensor events occurring over short periods of time.Thanks to this a link can be done between endangered bird species,such as the Siberian Crane and the Lesser White-Fronted Goose and periodically flooded areas.These midterm results illustrated the pertinence and powerful of multi-source optical satellite data for enviro展开更多
The various mutations in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pose a substantial challenge in mitigating the viral infectivity.The identification of novel host factors influencing SARS-CoV-2 repl...The various mutations in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pose a substantial challenge in mitigating the viral infectivity.The identification of novel host factors influencing SARS-CoV-2 replication holds potential for discovering new targets for broad-spectrum antiviral drugs that can combat future viral mutations.In this study,potential host factors regulated by SARS-CoV-2 infection were screened through different high-throughput sequencing techniques and further identified in cells.Subsequent analysis and experiments showed that the reduction of m6A modification level on ACTN4(Alpha-actinin-4)mRNA leads to a decrease in mRNA stability and translation efficiency,ultimately inhibiting ACTN4 expression.In addition,ACTN4 was demonstrated to target nsp12 for binding and characterized as a competitor for SARS-CoV-2 RNA and the RNA-dependent RNA polymerase complex,thereby impeding viral replication.Furthermore,two ACTN4 agonists,YS-49 and demethyl-coclaurine,were found to dose-dependently inhibit SARS-CoV-2 infection in both Huh7 cells and K18-hACE2 transgenic mice.Collectively,this study unveils the pivotal role of ACTN4 in SARS-CoV-2 infection,offering novel insights into the intricate interplay between the virus and host cells,and reveals two potential candidates for future anti-SARS-CoV-2 drug development.展开更多
Film-stalk spaced dual mulching is a new type of cultivation measure that is increasingly highlighted in semi-arid areas in China.Despite its potential,there is limited understanding of how different mulching material...Film-stalk spaced dual mulching is a new type of cultivation measure that is increasingly highlighted in semi-arid areas in China.Despite its potential,there is limited understanding of how different mulching materials affect both soil quality and crop yield in these areas.To address this gap,we conducted a two-year(2020-2021)field experiment in central China to explore the yield-enhancing mechanisms and assess the impact of various mulching materials on soil and corn yield.The experiment comprised six treatments,i.e.,plastic film-whole stalk spaced mulching in fall(PSF),plastic film-whole stalk spaced mulching in spring(PSS),black and silver plastic film-whole stalk spaced mulching in spring(BPSS),biodegradable film-whole stalk spaced mulching in spring(BSS),liquid film-whole stalk spaced mulching in spring(LSS),and non-mulching cultivation(CK).Results revealed that BPSS demonstrated the most significant yield increase,surpassing CK by a notable 10.0%and other mulching treatments by 2.4%-5.9%.The efficacy of BPSS lied in its provision of favorable hydrothermal conditions for corn cultivation,particularly during hot season.Its cooling effect facilitated the establishment of optimal temperature conditions relative to transparent mulching,leading to higher root growth indices(e.g.,length and surface area),as well as higher leaf photosynthetic rate and dry matter accumulation per plant.Additionally,BPSS maintained higher average soil moisture content within 0-100 cm depth compared with biodegradable mulching and liquid mulching.As a result,BPSS increased activities of urease,catalase,and alkaline phosphatase,as well as the diversity and abundance of soil bacteria and fungi in the rhizosphere zone of corn,facilitating nutrient accessibility by the plant.These findings suggest that selecting appropriate mulching materials is crucial for optimizing corn production in drought-prone areas,highlighting the potential of BPSS cultivation.展开更多
文摘As part of the Dragon 4 project,the water extents of Wuchang and Shengjin lakes have been extracted from Sentinel-2 time series,using all exploitable images since the beginning of the acquisitions in 2015.The aim of the study is to assess the capability of the Sentinel-2 constellation and Landsat 8 over the Anhui region,especially the high temporal resolution.A total of 32 dates have been used and 10 Landsat 8 images(Libra)have been added to try to reduce the temporal gaps in the Sentinel-2 acquisitions caused by cloudy conditions.Extractions were done using a SERTIT-ICube automatized routine based on a supervised Maximum Likelihood Classification.These extractions allow to recreate the dynamic of the two lakes and show the drought and wet periods.During the 3 years interval,the surface peaks in July 2016 for both lakes.The lowest level appears at two different dates for each lake;in January 2018 for Wuchang,in February 2017 for Shengjin.Wuchang Lake surface area appears to be more variable than Shengjin Lake,with many local maximum and minimum between the end of 2017 and April 2018.In the case of Wuchang Lake,floating vegetation is a problem for automatic water surface area extraction.The lake is covered by vegetation during long periods of time and the water below can’t be detected by automatic radiometric means.Nevertheless,Sentinel-2 stays a pertinent and powerful tool for hydrological monitoring of lakes confirming the expectation from the remote sensing wetland community before launch.The presence of NIR and SWIR bands induces a strong discrimination between water and other classes,and the systematic acquisitions create dense time series,making analysis more consistent.It makes possible to sensor events occurring over short periods of time.Thanks to this a link can be done between endangered bird species,such as the Siberian Crane and the Lesser White-Fronted Goose and periodically flooded areas.These midterm results illustrated the pertinence and powerful of multi-source optical satellite data for enviro
基金National Natural Science Foundation of China[31970168]Hubei Science and Technology Major Project[2021ACB004]+1 种基金Key R&D Program of Hubei Province[2021BCD004]Hubei Central Leading Local Science and Technology Special Project[2022BGE245].
文摘The various mutations in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pose a substantial challenge in mitigating the viral infectivity.The identification of novel host factors influencing SARS-CoV-2 replication holds potential for discovering new targets for broad-spectrum antiviral drugs that can combat future viral mutations.In this study,potential host factors regulated by SARS-CoV-2 infection were screened through different high-throughput sequencing techniques and further identified in cells.Subsequent analysis and experiments showed that the reduction of m6A modification level on ACTN4(Alpha-actinin-4)mRNA leads to a decrease in mRNA stability and translation efficiency,ultimately inhibiting ACTN4 expression.In addition,ACTN4 was demonstrated to target nsp12 for binding and characterized as a competitor for SARS-CoV-2 RNA and the RNA-dependent RNA polymerase complex,thereby impeding viral replication.Furthermore,two ACTN4 agonists,YS-49 and demethyl-coclaurine,were found to dose-dependently inhibit SARS-CoV-2 infection in both Huh7 cells and K18-hACE2 transgenic mice.Collectively,this study unveils the pivotal role of ACTN4 in SARS-CoV-2 infection,offering novel insights into the intricate interplay between the virus and host cells,and reveals two potential candidates for future anti-SARS-CoV-2 drug development.
基金financially supported by the Projects of National Key Research and Development Program of China(2021YFD1901101-5)the Special Major Research and Development Project of Shanxi Province(202101140601026-5)the Earmarked Fund for Modern Agro-industry Technology Research System(2023CYJSTX01-11).
文摘Film-stalk spaced dual mulching is a new type of cultivation measure that is increasingly highlighted in semi-arid areas in China.Despite its potential,there is limited understanding of how different mulching materials affect both soil quality and crop yield in these areas.To address this gap,we conducted a two-year(2020-2021)field experiment in central China to explore the yield-enhancing mechanisms and assess the impact of various mulching materials on soil and corn yield.The experiment comprised six treatments,i.e.,plastic film-whole stalk spaced mulching in fall(PSF),plastic film-whole stalk spaced mulching in spring(PSS),black and silver plastic film-whole stalk spaced mulching in spring(BPSS),biodegradable film-whole stalk spaced mulching in spring(BSS),liquid film-whole stalk spaced mulching in spring(LSS),and non-mulching cultivation(CK).Results revealed that BPSS demonstrated the most significant yield increase,surpassing CK by a notable 10.0%and other mulching treatments by 2.4%-5.9%.The efficacy of BPSS lied in its provision of favorable hydrothermal conditions for corn cultivation,particularly during hot season.Its cooling effect facilitated the establishment of optimal temperature conditions relative to transparent mulching,leading to higher root growth indices(e.g.,length and surface area),as well as higher leaf photosynthetic rate and dry matter accumulation per plant.Additionally,BPSS maintained higher average soil moisture content within 0-100 cm depth compared with biodegradable mulching and liquid mulching.As a result,BPSS increased activities of urease,catalase,and alkaline phosphatase,as well as the diversity and abundance of soil bacteria and fungi in the rhizosphere zone of corn,facilitating nutrient accessibility by the plant.These findings suggest that selecting appropriate mulching materials is crucial for optimizing corn production in drought-prone areas,highlighting the potential of BPSS cultivation.
