Load balancing is vital for the efficient and long-term operation of cloud data centers.With virtualization,post(reactive)migration of virtual machines(VMs)after allocation is the traditional way for load balancing an...Load balancing is vital for the efficient and long-term operation of cloud data centers.With virtualization,post(reactive)migration of virtual machines(VMs)after allocation is the traditional way for load balancing and consolidation.However,it is not easy for reactive migration to obtain predefined load balance objectives and it may interrupt services and bring instability.Therefore,we provide a new approach,called Prepartition,for load balancing.It partitions a VM request into a few sub-requests sequentially with start time,end time and capacity demands,and treats each sub-request as a regular VM request.In this way,it can proactively set a bound for each VM request on each physical machine and makes the scheduler get ready before VM migration to obtain the predefined load balancing goal,which supports the resource allocation in a fine-grained manner.Simulations with real-world trace and synthetic data show that our proposed approach with offline version(PrepartitionOff)scheduling has 10%–20%better performance than the existing load balancing baselines under several metrics,including average utilization,imbalance degree,makespan and Capacity_makespan.We also extend Prepartition to online load balancing.Evaluation results show that our proposed approach also outperforms state-of-the-art online algorithms.展开更多
红外激光变频技术急需新型的具有优良性能的非线性光学晶体,但获得能够实现大倍频和高激光损伤阈值平衡的新型红外非线性光学晶体依然是巨大的挑战,进一步的工作仍是科研工作者的研究热点.本文通过高温溶液法将高正电性的碱金属锂,碱土...红外激光变频技术急需新型的具有优良性能的非线性光学晶体,但获得能够实现大倍频和高激光损伤阈值平衡的新型红外非线性光学晶体依然是巨大的挑战,进一步的工作仍是科研工作者的研究热点.本文通过高温溶液法将高正电性的碱金属锂,碱土金属钡以及无机半导体硅与硒熔合高温反应得到了一种新型红外非线性光学晶体Li2Ba Si Se4,并获得了其光学性质的实验数据.经过漫反射数据转化得到的光学带隙实验值为2.47e V,2.09μm光源下的倍频效应与商业化使用的AgGaS2相当,约为KH2PO4(KDP)的30倍.第一性原理计算还分析了它的能带结构、态密度分布等.展开更多
Objective:To observe the changes of ischemic myocardial cells apoptosis in rats following intervention with Xuefu Zhuyu Oral Liquid(血府逐瘀口服液,XFZY),as well as changes of protein expression of silent information r...Objective:To observe the changes of ischemic myocardial cells apoptosis in rats following intervention with Xuefu Zhuyu Oral Liquid(血府逐瘀口服液,XFZY),as well as changes of protein expression of silent information regulator 1(SIRT1)and SIRT1 pathway-related genes.Methods:H9c2 rat myocardial cells were divided into 6 groups:control group,oxygen glucose deprivation(OGD)group,SIRT1 siRNA group,OGD+SIRT1 siRNA group,OGD+XFZY group,and OGD+SIRT1 siRNA+XFZY group.Quantitative fluorescent polymerase chain reaction(PCR)and Western blot were used to detect the concentration variations of SIRT1 and its pathway-related genes and corresponding protein expression after XFZY intervention and SIRT1 transfection.Results:Compared with the control group,the mRNA and protein expressions of SIRT1 were decreased obviously,while the mRNA and protein levels of P53,forkhead box protein O1(FoxO1),FoxO3,FoxO4 and nuclear factor kappa B(NF-κB)were increased in the OGD group,SIRT1 siRNA group,and OGD+SIRT1 siRNA group(P<0.01).Compared with the OGD group and OGD+SIRT1 siRNA group,the treatment of XFZY inhibited the decline in SIRT1 mRNA and protein expressions(P<0.01),and down-regulated the mRNA and protein levels of P53,FoxO1,FoxO3,FoxO4 and NF-κB,respectively(P<0.05 or P<0.01).Conclusion:XFZY could prevent myocardial cells apoptosis probably by increasing the mRNA and protein expressions of SIRT1 and inhibiting the mRNA and protein expressions of P53,NF-κB,FoxO1,FoxO3 and FoxO4.展开更多
In view of particularity and complexity of agricultural sci-tech service and management,this paper presents definition of basic concept of agricultural sci-tech service and management,sums up its basic characteristics...In view of particularity and complexity of agricultural sci-tech service and management,this paper presents definition of basic concept of agricultural sci-tech service and management,sums up its basic characteristics,and discusses and analyzes its structural elements and functions. The agricultural sci-tech service and management plays an important role in speeding up rural construction and narrowing the gap between urban and rural areas. It ensures benign cycle of scientific and technological achievements and regional environment,and promotes development of agricultural industrialization.展开更多
基金supported by Shenzhen Industrial Application Projects of undertaking the National Key Research and Development Program of China under Grant No.CJGJZD20210408091600002the National Natural Science Foundation of China under Grant No.62102408Shenzhen Science and Technology Program under Grant No.RCBS20210609104609044.
文摘Load balancing is vital for the efficient and long-term operation of cloud data centers.With virtualization,post(reactive)migration of virtual machines(VMs)after allocation is the traditional way for load balancing and consolidation.However,it is not easy for reactive migration to obtain predefined load balance objectives and it may interrupt services and bring instability.Therefore,we provide a new approach,called Prepartition,for load balancing.It partitions a VM request into a few sub-requests sequentially with start time,end time and capacity demands,and treats each sub-request as a regular VM request.In this way,it can proactively set a bound for each VM request on each physical machine and makes the scheduler get ready before VM migration to obtain the predefined load balancing goal,which supports the resource allocation in a fine-grained manner.Simulations with real-world trace and synthetic data show that our proposed approach with offline version(PrepartitionOff)scheduling has 10%–20%better performance than the existing load balancing baselines under several metrics,including average utilization,imbalance degree,makespan and Capacity_makespan.We also extend Prepartition to online load balancing.Evaluation results show that our proposed approach also outperforms state-of-the-art online algorithms.
文摘红外激光变频技术急需新型的具有优良性能的非线性光学晶体,但获得能够实现大倍频和高激光损伤阈值平衡的新型红外非线性光学晶体依然是巨大的挑战,进一步的工作仍是科研工作者的研究热点.本文通过高温溶液法将高正电性的碱金属锂,碱土金属钡以及无机半导体硅与硒熔合高温反应得到了一种新型红外非线性光学晶体Li2Ba Si Se4,并获得了其光学性质的实验数据.经过漫反射数据转化得到的光学带隙实验值为2.47e V,2.09μm光源下的倍频效应与商业化使用的AgGaS2相当,约为KH2PO4(KDP)的30倍.第一性原理计算还分析了它的能带结构、态密度分布等.
基金financially supported by the National Natural Science Foundation of China(Nos.52071347,51971205)the Innovation Group Project of Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai),China(No.311020012)。
基金Supported by the National Natural Science Foundation of China(Nos.81173449,81473466)。
文摘Objective:To observe the changes of ischemic myocardial cells apoptosis in rats following intervention with Xuefu Zhuyu Oral Liquid(血府逐瘀口服液,XFZY),as well as changes of protein expression of silent information regulator 1(SIRT1)and SIRT1 pathway-related genes.Methods:H9c2 rat myocardial cells were divided into 6 groups:control group,oxygen glucose deprivation(OGD)group,SIRT1 siRNA group,OGD+SIRT1 siRNA group,OGD+XFZY group,and OGD+SIRT1 siRNA+XFZY group.Quantitative fluorescent polymerase chain reaction(PCR)and Western blot were used to detect the concentration variations of SIRT1 and its pathway-related genes and corresponding protein expression after XFZY intervention and SIRT1 transfection.Results:Compared with the control group,the mRNA and protein expressions of SIRT1 were decreased obviously,while the mRNA and protein levels of P53,forkhead box protein O1(FoxO1),FoxO3,FoxO4 and nuclear factor kappa B(NF-κB)were increased in the OGD group,SIRT1 siRNA group,and OGD+SIRT1 siRNA group(P<0.01).Compared with the OGD group and OGD+SIRT1 siRNA group,the treatment of XFZY inhibited the decline in SIRT1 mRNA and protein expressions(P<0.01),and down-regulated the mRNA and protein levels of P53,FoxO1,FoxO3,FoxO4 and NF-κB,respectively(P<0.05 or P<0.01).Conclusion:XFZY could prevent myocardial cells apoptosis probably by increasing the mRNA and protein expressions of SIRT1 and inhibiting the mRNA and protein expressions of P53,NF-κB,FoxO1,FoxO3 and FoxO4.
文摘In view of particularity and complexity of agricultural sci-tech service and management,this paper presents definition of basic concept of agricultural sci-tech service and management,sums up its basic characteristics,and discusses and analyzes its structural elements and functions. The agricultural sci-tech service and management plays an important role in speeding up rural construction and narrowing the gap between urban and rural areas. It ensures benign cycle of scientific and technological achievements and regional environment,and promotes development of agricultural industrialization.
