目的:膝关节镜治疗对轻中度膝骨关节炎具有良好疗效,但在术中灌洗液会带走大量原有关节液,术后通过注射玻璃酸钠补充关节液能否进一步提高疗效尚存争议。文章评价关节镜联合玻璃酸钠治疗相较于单纯关节镜治疗膝骨关节炎的疗效。方法:检...目的:膝关节镜治疗对轻中度膝骨关节炎具有良好疗效,但在术中灌洗液会带走大量原有关节液,术后通过注射玻璃酸钠补充关节液能否进一步提高疗效尚存争议。文章评价关节镜联合玻璃酸钠治疗相较于单纯关节镜治疗膝骨关节炎的疗效。方法:检索中国知网、万方、维普、CBM、PubMed、Web of Science、EMBASE及Cochrane Library数据库,检索建库至2020-03-27相关文献,纳入关节镜联合玻璃酸钠治疗膝骨关节炎的随机对照试验,对符合标准的试验采用Cochrane系统评价方法进行评价,采用Revman 5.3软件进行Meta分析。主要结局指标为Lequesne评分、Lysholm评分、WOMAC评分和目测类比评分;次要结局指标为关节液中肿瘤坏死因子α、白细胞介素1β及白细胞介素6水平。结果:共纳入31个随机对照试验,研究对象1350例。Meta分析结果显示:①联合组Lequesne评分在术后1周(MD=-0.33,95%CI:0.67至-0.00,P=0.05)、玻璃酸钠注射疗程结束后(MD=-1.00,95%CI:-1.34至-0.66,P<0.00001)、术后3个月(MD=-1.04,95%CI:-1.44至-0.64,P<0.00001)均优于对照组;②联合组Lysholm评分在术后1周(MD=5.84,95%CI:4.79-6.88,P<0.00001)、玻璃酸钠注射疗程结束后(MD=9.21,95%CI:6.93-11.49,P<0.00001)、术后3个月(MD=9.14,95%CI:6.34-11.94,P<0.00001)、术后半年(MD=10.14,95%CI:6.50-13.78,P<0.00001)、术后1年(MD=11.54,95%CI:9.92-13.16,P<0.00001)均优于对照组;③联合组WOMAC评分在术后1年(MD=-18.38,95%CI:-28.53至-8.23,P=0.0004)优于对照组;联合组目测类比评分在术后1周(MD=-0.91,95%CI:-1.11至-0.72,P<0.00001)、玻璃酸钠注射疗程结束后(MD=-0.97,95%CI:-1.23至-0.72,P<0.00001)、术后3个月(MD=-0.41,95%CI:-0.52,-0.31,P<0.00001)均优于对照组;④联合组在治疗全疗程结束后相较于注射1周后Lequense评分(MD=1.47,95%CI:1.14-1.80,P<0.00001)更优;⑤联合组更好地降低关节液中肿瘤坏死因子α、白细胞介素1β及白细胞介素6水平(P≤0.05),能更好地控制炎症�展开更多
An improved understanding of biodiversity-productivity relationships(BPRs)along environmental gradients is crucial for effective ecosystem management and biodiversity conservation.The stress-gradient hypothesis sugges...An improved understanding of biodiversity-productivity relationships(BPRs)along environmental gradients is crucial for effective ecosystem management and biodiversity conservation.The stress-gradient hypothesis suggests that BPRs are stronger in stressful environments compared to more favorable conditions.However,there is limited knowledge regarding the variation of BPRs along elevational gradients and their generality across different landscapes.To study how BPRs change with elevation,we harnessed inventory data on 6,431 trees from152 plots surveyed twice in eight to ten year intervals in mountain forests of temperate Europe and subtropical Asia.We quantified the relationship between aboveground productivity and different biodiversity measures,including taxonomic,functional,and phylogenetic diversity.To elucidate the processes underlying BPRs,we studied the variation of different functional traits along elevation across landscapes.We found no general pattern of BPRs across landscapes and elevations.Relationships were neutral for all biodiversity measures in temperate forests,and negative for taxonomic and functional diversity in subtropical forests.BPRs were largely congruent between taxonomic,functional and phylogenetic diversity.We found only weak support for the stress-gradient hypothesis,with BPRs turning from negative to positive(effect not significant)close to the tree line in subtropical forests.In temperate forests,however,elevation patterns were strongly modulated by species identity effects as influenced by specific traits.The effect of traits such as community-weighted mean of maximum plant height and wood density on productivity was congruent across landscapes.Our study highlights the context-dependence of BPRs across elevation gradients and landscapes.Species traits are key modulating factors of BPRs and should be considered more explicitly in studies of the functional role of biodiversity.Furthermore,our findings highlight that potential trade-offs between conserving biodiversity and fostering ecos展开更多
Trajectories of flying hot particles were predicted in this work, and the temperatures during the movement were also calculated. Once the particle tem- perature decreased to the critical temperature for a hot particle...Trajectories of flying hot particles were predicted in this work, and the temperatures during the movement were also calculated. Once the particle tem- perature decreased to the critical temperature for a hot particle to ignite building insulation materials, which was predicted by hot-spot ignition theory, the distance particle traveled was determined as the minimum safety distance for preventing the ignition of building insulation materials by hot particles. The results showed that for sphere aluminum particles with the same initial velocities and diameters, the horizontal and vertical distances traveled by particles with higher initial tem- peratures were higher. Smaller particles traveled farther when other conditions were the same. The critical temperature for an aluminum particle to ignite rigid polyurethane foam increased rapidly with the decrease of particle diameter. The horizontal and vertical safety distances were closely related to the initial temper- ature, diameter and initial velocity of particles. These results could help update the safety provision of firework display.展开更多
目的基于国内外文献,梳理肠道微生态在中医药领域的研究情况,分析其研究热点及研究发展趋势。方法基于中国知网(CNKI)和Web of science(WOS)数据库,检索2000—2020年肠道微生态在中医药领域研究相关文献,应用CiteScape 5.8.R1版软件进...目的基于国内外文献,梳理肠道微生态在中医药领域的研究情况,分析其研究热点及研究发展趋势。方法基于中国知网(CNKI)和Web of science(WOS)数据库,检索2000—2020年肠道微生态在中医药领域研究相关文献,应用CiteScape 5.8.R1版软件进行作者、地区机构共现分析;关键词聚类、突显分析;WOS所收文献的共被引和突现分析。结果CNKI数据库纳入中文文献772条,WOS数据库纳入英文文献233条。2015年以后国内外有关肠道微生态在中医药领域的研究日趋深入,中英文年发文量呈显著上升趋势。杨景云、谭周进、蔡子微及QIAN等团队为国内外发文量较高作者;中国为中英文发文量排名第一的国家,影响力较高;南京中医药大学、北京中医药大学、上海中医药大学等是该领域中英文文献发表量较多且发挥重要桥梁作用的机构。研究热点关键词包括溃疡性结肠炎、菌群失调、糖尿病、生物转化机制等,主要内容涉及基于肠道菌群的中药防治疾病作用机制研究和临床研究、肠道菌与中药代谢、肠道菌群与中医药理论研究等方面。其中中草药通过肠道菌群干预糖脂代谢紊乱疾病、基于肠道菌群的中药功能性产品研发处于最新研究前沿。结论肠道微生态在中医药领域近10年研究逐渐活跃,取得突出成果,关注肠道微生态在中医药领域研究成果的应用可能是领域研究发展的关键。展开更多
There are magnetic interference problems in the applications of DC current comparator. Analysis on the magnetic effectiveness which is applied by the external magnetic field is introduced in this paper. The effectiven...There are magnetic interference problems in the applications of DC current comparator. Analysis on the magnetic effectiveness which is applied by the external magnetic field is introduced in this paper. The effectiveness is proved by the actual results which are compared with the magnetic- circuit method and the finite element method. In addition, the reference comment is given which can be used in the practical work of DC current comparator shield design.展开更多
Aiming at the deficiencies of notch filters on the aspect of vibration suppression for elastic missile with swing nozzle thrust vector control(SNTVC),an active vibration controller(AVC)is proposed.It is composed of an...Aiming at the deficiencies of notch filters on the aspect of vibration suppression for elastic missile with swing nozzle thrust vector control(SNTVC),an active vibration controller(AVC)is proposed.It is composed of an optimal state feedback controller(OSFC)and an optimal minimal order state observer(OMOSO),which can be respectively designed based on the separation principle.The design rules of these two elements are successively given.Computer simulation results present that AVC can realize strong vibration suppression and good convergence property after disturbing.Moreover,it has simple design and then it is easily implemented in engineering.In addition,the AVC scheme can also resolve the poor system stability to a great extent,which is resulted from the bad static stability of missile body.展开更多
文摘目的:膝关节镜治疗对轻中度膝骨关节炎具有良好疗效,但在术中灌洗液会带走大量原有关节液,术后通过注射玻璃酸钠补充关节液能否进一步提高疗效尚存争议。文章评价关节镜联合玻璃酸钠治疗相较于单纯关节镜治疗膝骨关节炎的疗效。方法:检索中国知网、万方、维普、CBM、PubMed、Web of Science、EMBASE及Cochrane Library数据库,检索建库至2020-03-27相关文献,纳入关节镜联合玻璃酸钠治疗膝骨关节炎的随机对照试验,对符合标准的试验采用Cochrane系统评价方法进行评价,采用Revman 5.3软件进行Meta分析。主要结局指标为Lequesne评分、Lysholm评分、WOMAC评分和目测类比评分;次要结局指标为关节液中肿瘤坏死因子α、白细胞介素1β及白细胞介素6水平。结果:共纳入31个随机对照试验,研究对象1350例。Meta分析结果显示:①联合组Lequesne评分在术后1周(MD=-0.33,95%CI:0.67至-0.00,P=0.05)、玻璃酸钠注射疗程结束后(MD=-1.00,95%CI:-1.34至-0.66,P<0.00001)、术后3个月(MD=-1.04,95%CI:-1.44至-0.64,P<0.00001)均优于对照组;②联合组Lysholm评分在术后1周(MD=5.84,95%CI:4.79-6.88,P<0.00001)、玻璃酸钠注射疗程结束后(MD=9.21,95%CI:6.93-11.49,P<0.00001)、术后3个月(MD=9.14,95%CI:6.34-11.94,P<0.00001)、术后半年(MD=10.14,95%CI:6.50-13.78,P<0.00001)、术后1年(MD=11.54,95%CI:9.92-13.16,P<0.00001)均优于对照组;③联合组WOMAC评分在术后1年(MD=-18.38,95%CI:-28.53至-8.23,P=0.0004)优于对照组;联合组目测类比评分在术后1周(MD=-0.91,95%CI:-1.11至-0.72,P<0.00001)、玻璃酸钠注射疗程结束后(MD=-0.97,95%CI:-1.23至-0.72,P<0.00001)、术后3个月(MD=-0.41,95%CI:-0.52,-0.31,P<0.00001)均优于对照组;④联合组在治疗全疗程结束后相较于注射1周后Lequense评分(MD=1.47,95%CI:1.14-1.80,P<0.00001)更优;⑤联合组更好地降低关节液中肿瘤坏死因子α、白细胞介素1β及白细胞介素6水平(P≤0.05),能更好地控制炎症�
基金supported by the Sino-German Postdoc Scholarship Program of the China Scholarship Council(CSC)the German Academic Exchange Service(DAAD)+4 种基金supported in part by the National Natural Science Foundation of China(Nos.32071541,41971071)the Ministry of Science and Technology of China(Nos.2021FY100200,2021FY100702,2023YFF0805802)the Youth Innovation Promotion Association,CAS(No.2021392)the International Partnership Program,CAS(No.151853KYSB20190027)the“Climate Change Research Initiative of the Bavarian National Parks”funded by the Bavarian State Ministry of the Environment and Consumer Protection.
文摘An improved understanding of biodiversity-productivity relationships(BPRs)along environmental gradients is crucial for effective ecosystem management and biodiversity conservation.The stress-gradient hypothesis suggests that BPRs are stronger in stressful environments compared to more favorable conditions.However,there is limited knowledge regarding the variation of BPRs along elevational gradients and their generality across different landscapes.To study how BPRs change with elevation,we harnessed inventory data on 6,431 trees from152 plots surveyed twice in eight to ten year intervals in mountain forests of temperate Europe and subtropical Asia.We quantified the relationship between aboveground productivity and different biodiversity measures,including taxonomic,functional,and phylogenetic diversity.To elucidate the processes underlying BPRs,we studied the variation of different functional traits along elevation across landscapes.We found no general pattern of BPRs across landscapes and elevations.Relationships were neutral for all biodiversity measures in temperate forests,and negative for taxonomic and functional diversity in subtropical forests.BPRs were largely congruent between taxonomic,functional and phylogenetic diversity.We found only weak support for the stress-gradient hypothesis,with BPRs turning from negative to positive(effect not significant)close to the tree line in subtropical forests.In temperate forests,however,elevation patterns were strongly modulated by species identity effects as influenced by specific traits.The effect of traits such as community-weighted mean of maximum plant height and wood density on productivity was congruent across landscapes.Our study highlights the context-dependence of BPRs across elevation gradients and landscapes.Species traits are key modulating factors of BPRs and should be considered more explicitly in studies of the functional role of biodiversity.Furthermore,our findings highlight that potential trade-offs between conserving biodiversity and fostering ecos
基金supported by the National Basic Research Program of China(2012CB719702)the International Science&Technology Cooperation Program of China(2014DFG72300)the Fundamental Research Funds for the Central University(WK2320000014)
文摘Trajectories of flying hot particles were predicted in this work, and the temperatures during the movement were also calculated. Once the particle tem- perature decreased to the critical temperature for a hot particle to ignite building insulation materials, which was predicted by hot-spot ignition theory, the distance particle traveled was determined as the minimum safety distance for preventing the ignition of building insulation materials by hot particles. The results showed that for sphere aluminum particles with the same initial velocities and diameters, the horizontal and vertical distances traveled by particles with higher initial tem- peratures were higher. Smaller particles traveled farther when other conditions were the same. The critical temperature for an aluminum particle to ignite rigid polyurethane foam increased rapidly with the decrease of particle diameter. The horizontal and vertical safety distances were closely related to the initial temper- ature, diameter and initial velocity of particles. These results could help update the safety provision of firework display.
文摘目的基于国内外文献,梳理肠道微生态在中医药领域的研究情况,分析其研究热点及研究发展趋势。方法基于中国知网(CNKI)和Web of science(WOS)数据库,检索2000—2020年肠道微生态在中医药领域研究相关文献,应用CiteScape 5.8.R1版软件进行作者、地区机构共现分析;关键词聚类、突显分析;WOS所收文献的共被引和突现分析。结果CNKI数据库纳入中文文献772条,WOS数据库纳入英文文献233条。2015年以后国内外有关肠道微生态在中医药领域的研究日趋深入,中英文年发文量呈显著上升趋势。杨景云、谭周进、蔡子微及QIAN等团队为国内外发文量较高作者;中国为中英文发文量排名第一的国家,影响力较高;南京中医药大学、北京中医药大学、上海中医药大学等是该领域中英文文献发表量较多且发挥重要桥梁作用的机构。研究热点关键词包括溃疡性结肠炎、菌群失调、糖尿病、生物转化机制等,主要内容涉及基于肠道菌群的中药防治疾病作用机制研究和临床研究、肠道菌与中药代谢、肠道菌群与中医药理论研究等方面。其中中草药通过肠道菌群干预糖脂代谢紊乱疾病、基于肠道菌群的中药功能性产品研发处于最新研究前沿。结论肠道微生态在中医药领域近10年研究逐渐活跃,取得突出成果,关注肠道微生态在中医药领域研究成果的应用可能是领域研究发展的关键。
文摘There are magnetic interference problems in the applications of DC current comparator. Analysis on the magnetic effectiveness which is applied by the external magnetic field is introduced in this paper. The effectiveness is proved by the actual results which are compared with the magnetic- circuit method and the finite element method. In addition, the reference comment is given which can be used in the practical work of DC current comparator shield design.
文摘Aiming at the deficiencies of notch filters on the aspect of vibration suppression for elastic missile with swing nozzle thrust vector control(SNTVC),an active vibration controller(AVC)is proposed.It is composed of an optimal state feedback controller(OSFC)and an optimal minimal order state observer(OMOSO),which can be respectively designed based on the separation principle.The design rules of these two elements are successively given.Computer simulation results present that AVC can realize strong vibration suppression and good convergence property after disturbing.Moreover,it has simple design and then it is easily implemented in engineering.In addition,the AVC scheme can also resolve the poor system stability to a great extent,which is resulted from the bad static stability of missile body.
