This study proposes a novel general image fusion framework based on cross-domain long-range learning and Swin Transformer,termed as SwinFusion.On the one hand,an attention-guided cross-domain module is devised to achi...This study proposes a novel general image fusion framework based on cross-domain long-range learning and Swin Transformer,termed as SwinFusion.On the one hand,an attention-guided cross-domain module is devised to achieve sufficient integration of complementary information and global interaction.More specifically,the proposed method involves an intra-domain fusion unit based on self-attention and an interdomain fusion unit based on cross-attention,which mine and integrate long dependencies within the same domain and across domains.Through long-range dependency modeling,the network is able to fully implement domain-specific information extraction and cross-domain complementary information integration as well as maintaining the appropriate apparent intensity from a global perspective.In particular,we introduce the shifted windows mechanism into the self-attention and cross-attention,which allows our model to receive images with arbitrary sizes.On the other hand,the multi-scene image fusion problems are generalized to a unified framework with structure maintenance,detail preservation,and proper intensity control.Moreover,an elaborate loss function,consisting of SSIM loss,texture loss,and intensity loss,drives the network to preserve abundant texture details and structural information,as well as presenting optimal apparent intensity.Extensive experiments on both multi-modal image fusion and digital photography image fusion demonstrate the superiority of our SwinFusion compared to the state-of-theart unified image fusion algorithms and task-specific alternatives.Implementation code and pre-trained weights can be accessed at https://github.com/Linfeng-Tang/SwinFusion.展开更多
Dear Editor,Plant viruses make up almost half of the plant disease-causing pathogens,affecting crop yields and the global economy(Savary et al.,2019).Soybean(Glycine max)is one of the most valuable legume crops in the...Dear Editor,Plant viruses make up almost half of the plant disease-causing pathogens,affecting crop yields and the global economy(Savary et al.,2019).Soybean(Glycine max)is one of the most valuable legume crops in the world,supplying 25%of the global edible oil and two-thirds of the global concentrated protein for livestock feeding.Recently,the outbreak of soybean stay-green syndrome with delayed leaf senescence(stay-green),flat pods,and increased number of abnormal seeds has swept the soybean production in the Huang-Huai-Hai region of China,resulting in huge yield losses(Xu et al.,2019).This disease has become an epidemic and prominent problem in soybean production and is still expanding its geography,including North America,posing a serious threat to soybean production(Harbach et al.,2016;Zhang et al.,2016;Li et al.,2019).However,the cause of soybean stay-green syndrome remains obscure.展开更多
We sought to examine the regulatory effect of Meteorin-β(Metrnβ)/Meteorin like(Metrnl)/IL-41 on lung inflammation in allergic asthma.We found that Metrnβwas elevated significantly in asthmatic patients and in mice ...We sought to examine the regulatory effect of Meteorin-β(Metrnβ)/Meteorin like(Metrnl)/IL-41 on lung inflammation in allergic asthma.We found that Metrnβwas elevated significantly in asthmatic patients and in mice with allergic asthma induced by house dust mite(HDM)extract.Upon exposure to HDM,Metrnβwas secreted predominantly by airway epithelial cells and inflammatory cells,including macrophages and eosinophils.The increased Metrnβeffectively blocked the development of airway hyperreactivity(AHR)and decreased inflammatory cell airway infiltration and type 2 cytokine production,which was associated with downregulated DC-mediated adaptive immune responses.Moreover,Metrnβimpaired the maturation and function of bone marrow-derived dendritic cells in vitro.Asthmatic mice adoptively transferred with dendritic cells isolated from Metrnβ-treated allergic mice displayed decreased AHR,airway inflammation,and lung injury.Metrnβalso displayed anti-inflammatory properties in immunodeficient SCID mice with allergic asthma and in in vitro 3D ALI airway models.Moreover,blockade of Metrnβby anti-Metrnβantibody treatment promoted the development of allergic asthma.These results revealed the unappreciated protective roles of Metrnβin alleviating DC-mediated Th2 inflammation in allergic asthma,providing the novel treatment strategy of therapeutic targeting of Metrnβin allergic asthma.展开更多
基金This work was supported by the National Natural Science Foundation of China(62075169,62003247,62061160370)the Key Research and Development Program of Hubei Province(2020BAB113).
文摘This study proposes a novel general image fusion framework based on cross-domain long-range learning and Swin Transformer,termed as SwinFusion.On the one hand,an attention-guided cross-domain module is devised to achieve sufficient integration of complementary information and global interaction.More specifically,the proposed method involves an intra-domain fusion unit based on self-attention and an interdomain fusion unit based on cross-attention,which mine and integrate long dependencies within the same domain and across domains.Through long-range dependency modeling,the network is able to fully implement domain-specific information extraction and cross-domain complementary information integration as well as maintaining the appropriate apparent intensity from a global perspective.In particular,we introduce the shifted windows mechanism into the self-attention and cross-attention,which allows our model to receive images with arbitrary sizes.On the other hand,the multi-scene image fusion problems are generalized to a unified framework with structure maintenance,detail preservation,and proper intensity control.Moreover,an elaborate loss function,consisting of SSIM loss,texture loss,and intensity loss,drives the network to preserve abundant texture details and structural information,as well as presenting optimal apparent intensity.Extensive experiments on both multi-modal image fusion and digital photography image fusion demonstrate the superiority of our SwinFusion compared to the state-of-theart unified image fusion algorithms and task-specific alternatives.Implementation code and pre-trained weights can be accessed at https://github.com/Linfeng-Tang/SwinFusion.
基金supported by the grants from National Natural Science Foundation of China Grants 31925032 and 32172376the Startup Fund for Distinguished Scholars from Nanjing Agricultural University to Y.X.and the Fundamental Research Funds for the Central Universities(JCQY202104)。
文摘Dear Editor,Plant viruses make up almost half of the plant disease-causing pathogens,affecting crop yields and the global economy(Savary et al.,2019).Soybean(Glycine max)is one of the most valuable legume crops in the world,supplying 25%of the global edible oil and two-thirds of the global concentrated protein for livestock feeding.Recently,the outbreak of soybean stay-green syndrome with delayed leaf senescence(stay-green),flat pods,and increased number of abnormal seeds has swept the soybean production in the Huang-Huai-Hai region of China,resulting in huge yield losses(Xu et al.,2019).This disease has become an epidemic and prominent problem in soybean production and is still expanding its geography,including North America,posing a serious threat to soybean production(Harbach et al.,2016;Zhang et al.,2016;Li et al.,2019).However,the cause of soybean stay-green syndrome remains obscure.
基金supported by a Direct Grant for Research 2021/2022(Medicine Panel),project code:2020.011,The Chinese University of Hong Kong,Hong Kong,China.The funders of the study had no involvement in the study design,data collection,data analysis,interpretation,writing of the report,or decision to submit the paper for publication.
文摘We sought to examine the regulatory effect of Meteorin-β(Metrnβ)/Meteorin like(Metrnl)/IL-41 on lung inflammation in allergic asthma.We found that Metrnβwas elevated significantly in asthmatic patients and in mice with allergic asthma induced by house dust mite(HDM)extract.Upon exposure to HDM,Metrnβwas secreted predominantly by airway epithelial cells and inflammatory cells,including macrophages and eosinophils.The increased Metrnβeffectively blocked the development of airway hyperreactivity(AHR)and decreased inflammatory cell airway infiltration and type 2 cytokine production,which was associated with downregulated DC-mediated adaptive immune responses.Moreover,Metrnβimpaired the maturation and function of bone marrow-derived dendritic cells in vitro.Asthmatic mice adoptively transferred with dendritic cells isolated from Metrnβ-treated allergic mice displayed decreased AHR,airway inflammation,and lung injury.Metrnβalso displayed anti-inflammatory properties in immunodeficient SCID mice with allergic asthma and in in vitro 3D ALI airway models.Moreover,blockade of Metrnβby anti-Metrnβantibody treatment promoted the development of allergic asthma.These results revealed the unappreciated protective roles of Metrnβin alleviating DC-mediated Th2 inflammation in allergic asthma,providing the novel treatment strategy of therapeutic targeting of Metrnβin allergic asthma.
