Objective To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH i...Objective To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH in a genetically homogenous Mongolia rural population of China. Methods Individuals (n=1099) were recruited from general population of Kezuohouqi Banner in Inner Mongolian Autonomous Region. Results The association was found between ACE genotype DD plus ID and EH, with an interaction between ACE genotype DD plus ID and cigarette smoking in an additive model. Cigarette smoking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 7.10 to 1.16. Interaction between ACE genotype DD plus ID and alcohol drinking on EH appeared an additive model. Alcohol drinking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 1.66 to 1.09. BMI and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 6.15 to 2.49. Interactions between ACE genotype and WHR on EH showed a multiplicative model. In a short, there was an interaction between ACE gene and cigarette smoking, alcohol drinking and BMI on EH, especially in a low dose-exposure effect Conclusion It is important for individuals who carry ACE D allele gene to prevent EH, and furthermore, to prevent and control coronary heart disease, in a view of population-based prevention.展开更多
Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales o...Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales of the embedding spaces. Based on a direction- relation matrix, the hierarchical frame of spatial direction relations which partitions direction relations orderly and thoroughly is built. Interior direction relations are used to perfect the representation of direction relations and the binary-encoding idea is creatively applied to construct an interior detailed matrix describing multiple interior direction relations by a uniform matrix. The model integrates topological information into the description model for direction relations, which will lay the foundations of spatial compositive reasoning.展开更多
This paper presents an analysis of an open-ended coaxial line sensor usedfor the dielectric propertty measurement or the bilayered biological tissues in vivo withwhich an analytical expression or sensor's fringi...This paper presents an analysis of an open-ended coaxial line sensor usedfor the dielectric propertty measurement or the bilayered biological tissues in vivo withwhich an analytical expression or sensor's fringing capacitances is derived. According tothis formula, an euquivalent circuit model of the open-ended coaxial line sensor is builtand a measurement method is designed for determining the dielectric properties or thebilayered materials. The theoretical results are compared with the experiment results,and it is shown that there is a good agreement between them.展开更多
基金This study was supported by Beijing Municipal Natural Sciences Foundation (Grant No. 7001004) Research Fund for the Doctoral Training Program from the Ministry of Education (Grant No. 20020023009) China Medical Board in New York (Grant No. 96-657).
文摘Objective To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH in a genetically homogenous Mongolia rural population of China. Methods Individuals (n=1099) were recruited from general population of Kezuohouqi Banner in Inner Mongolian Autonomous Region. Results The association was found between ACE genotype DD plus ID and EH, with an interaction between ACE genotype DD plus ID and cigarette smoking in an additive model. Cigarette smoking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 7.10 to 1.16. Interaction between ACE genotype DD plus ID and alcohol drinking on EH appeared an additive model. Alcohol drinking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 1.66 to 1.09. BMI and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 6.15 to 2.49. Interactions between ACE genotype and WHR on EH showed a multiplicative model. In a short, there was an interaction between ACE gene and cigarette smoking, alcohol drinking and BMI on EH, especially in a low dose-exposure effect Conclusion It is important for individuals who carry ACE D allele gene to prevent EH, and furthermore, to prevent and control coronary heart disease, in a view of population-based prevention.
文摘Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales of the embedding spaces. Based on a direction- relation matrix, the hierarchical frame of spatial direction relations which partitions direction relations orderly and thoroughly is built. Interior direction relations are used to perfect the representation of direction relations and the binary-encoding idea is creatively applied to construct an interior detailed matrix describing multiple interior direction relations by a uniform matrix. The model integrates topological information into the description model for direction relations, which will lay the foundations of spatial compositive reasoning.
文摘This paper presents an analysis of an open-ended coaxial line sensor usedfor the dielectric propertty measurement or the bilayered biological tissues in vivo withwhich an analytical expression or sensor's fringing capacitances is derived. According tothis formula, an euquivalent circuit model of the open-ended coaxial line sensor is builtand a measurement method is designed for determining the dielectric properties or thebilayered materials. The theoretical results are compared with the experiment results,and it is shown that there is a good agreement between them.
