The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapi...The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers.展开更多
The activation of HCl by cationic Au in the presence of C2H2 is important for the construction of active Au sites and in acetylene hydrochlorination.Here,we report a strategy for activating HCl by the Au-based support...The activation of HCl by cationic Au in the presence of C2H2 is important for the construction of active Au sites and in acetylene hydrochlorination.Here,we report a strategy for activating HCl by the Au-based supported ionic liquid phase(Au–SILP)technology with the[N(CN)2^–]anion.This strategy enables HCl to accept electrons from[N(CN)2^–]anions in Au–[N(CN)2^–]complexes rather than from pure[Bmim][N(CN)2],leading to notable improvement in both the reaction path and the stability of the catalyst without changing the reaction triggered by acetylene adsorption.Furthermore,the induction period of the Au–SILP catalyst was shown to be absent in the reaction process due to the high Au(III)content in the Au(Ⅲ)/Au(Ⅰ)site and the high substrate diffusion rate in the ionic liquid layer.This work provides a facile method to improve the stability of Au-based catalysts for acetylene hydrochlorination.展开更多
In order to obtain the seismic responses of the soil-rectangular tunnel structure,based on the PL-Finn constitutive model,four different conditions,namely,the liquefied soil around the rectangular tunnel,the liquefied...In order to obtain the seismic responses of the soil-rectangular tunnel structure,based on the PL-Finn constitutive model,four different conditions,namely,the liquefied soil around the rectangular tunnel,the liquefied soil below the rectangular tunnel,the liquefied soil on either side of the tunnel and the structure on non-liquefied soil,are compared.In accordance to the time at which a large deformation occurs,the possibility of destruction from hard to easy follows a descending order:the liquefied soil all around the structure,the liquefied soil on the bottom of the structure,and the liquefied soil on the two sides of the structure.The area of large deformation is mostly beneath the two arch angles of the tunnel floor.The soil on the two sides,especially close to the structure,is the hardest to liquefy and deform.The large deformation of soil caused by the liquefaction appears after the peak seismic value occurs.The higher the input seismic value is,the easier a large deformation can take place.With the same input of peak ground motion,the total displacement vector of the structure and differential displacement of the side-wall are in accordance with an order from large to small in the three situations:when the saturated sand is on two sides,all around the structure,and on the bottom of the structure.展开更多
Water constitutes the largest energy carrier on earth,absorbing more than 70%of the solar energy received by the earth's surface,yet its low exploitation has been a constant concern.The hydrovoltaic effect is an e...Water constitutes the largest energy carrier on earth,absorbing more than 70%of the solar energy received by the earth's surface,yet its low exploitation has been a constant concern.The hydrovoltaic effect is an emerging technology that generates electricity through the direct interaction between nanomaterials and water of various forms(raindrops,waves,flows,moisture,and natural evaporation).Especially,the evaporation-driven hydrovoltaic effect is a spontaneous and ubiquitous process that can directly convert thermal energy from the surrounding environment into electricity without the demand for additional mechanical work,which shows unique advantages compared with other hydrovoltaic effects.A variety of nanostructured materials have been steadily developed for evaporation-driven hydrovoltaic devices(EHDs)in recent years.However,there has been a lack of a clear specification on the selection and design of materials for improving device performance.Herein,we first analyze the mechanisms of EHDs followed by a summarization of the recent advances in materials,including carbon materials,biomass-based materials,metal oxides,composite materials,and others.We then discuss the strategies for improving the energy conversion efficiency and the output power in terms of structural design,surface modification,and interface treatment.Finally,we provide an outlook on the potential applications of electricity generation,sensors,and desalination technology,as well as the challenges and prospects for the development of this emerging technology in the future.展开更多
The effect of precipitation aging on the fracture behavior of cast Mg-14.23Gd-0.45Zr(wt.%)alloy at room temperature has been studied in this work.Uniaxial tensile and three-point bending tests were conducted on sample...The effect of precipitation aging on the fracture behavior of cast Mg-14.23Gd-0.45Zr(wt.%)alloy at room temperature has been studied in this work.Uniaxial tensile and three-point bending tests were conducted on samples peak-aged at 175,200,225,and 250 ℃.Notably,samples aged at 175 ℃ and 200 ℃ exhibited premature fracture during the uniaxial tensile test.Through fractographic observations of the tensile test samples and electron backscattered diffraction(EBSD)analysis on the samples sub-jected to three-point bending tests,a preferential formation of cleavage cracks in samples aged at 175 ℃ and 200 ℃ was identified as the reason for their premature fracture.The X-ray diffraction(XRD)results and transmission electron microscopy(TEM)observations of precipitates indicate that the dominant strengthening precipitates in all peak-aged samples are of theβ'phase,and their size significantly influences the formation of cleavage cracks.This phenomenon is attributed to the shearing mechanism of precipitates.Specifically,the smaller β'precipitates formed under the aging temperature of 175-200 ℃ are susceptible to dislocation shearing,leading to the formation of cleavage cracks.In contrast,the larger size of β'precipitates formed under the aging temperature of 225-250 ℃ provides resistance to shearing,resulting in the restrained formation of cleavage cracks and ultimately contributing to the enhancement of the ultimate tensile strength.展开更多
Rational design of catalytic sites to activate the C≡C bond is of paramount importance to advance acetylene hydrochlorination. Herein, Cu sites with electron-rich and electron-deficient states were constructed by con...Rational design of catalytic sites to activate the C≡C bond is of paramount importance to advance acetylene hydrochlorination. Herein, Cu sites with electron-rich and electron-deficient states were constructed by controlling the impregnation solutions. The π electrons flowing from acetylene to Cu site are facilitated over the electron-deficient Cu sites, achieving high activation of C≡C bond. The contradiction between the increased activation of acetylene required for enhanced catalytic activity and the resistance of Cu site to reduction by acetylene required for maintaining catalytic stability can be balanced by establishing strong interactions of Cu site with pyrrolic-N species. The catalytic activity displays a volcano shape scaling relationship as a function of Cu particle size. Tribasic copper chloride is concomitantly generated with the construction of electron-deficient Cu sites. The H–Cl bond of HCl can be activated over the tribasic copper chloride, accelerating the surface reaction of vinyl chloride production. This strategy of inducing electron deficiency provides new insight into the rational design of catalysts for the synthesis of vinyl chloride with a high catalytic performance.展开更多
For singularly perturbed convection-diffusion problems,supercloseness analysis of the finite element method is still open on Bakhvalov-type meshes,especially in the case of 2D.The difficulties arise from the width of ...For singularly perturbed convection-diffusion problems,supercloseness analysis of the finite element method is still open on Bakhvalov-type meshes,especially in the case of 2D.The difficulties arise from the width of the mesh in the layer adjacent to the transition point,resulting in a suboptimal estimate for convergence.Existing analysis techniques cannot handle these difficulties well.To fill this gap,here a novel interpolation is designed delicately for the smooth part of the solution,bringing about the optimal supercloseness result of almost order 2 under an energy norm for the finite element method.Our theoretical result is uniform in the singular perturbation parameterεand is supported by the numerical experiments.展开更多
基金supported by the Program for Changjiang Scholars and Innovative Research Team in University scheme of the Ministry of Education of China(NO.IRT1111)the National Basic Research Program of China(2012CB518300)+2 种基金the National Natural Science Foundation of China(81101946)the Shanghai Pujiang Program(12PJD008)Prostate Cancer Foundation Young Investigator Award,Shanghai Municipal Health and Family Planning Commission Outstanding Young Investigator(XYQ2013077).
文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers.
文摘The activation of HCl by cationic Au in the presence of C2H2 is important for the construction of active Au sites and in acetylene hydrochlorination.Here,we report a strategy for activating HCl by the Au-based supported ionic liquid phase(Au–SILP)technology with the[N(CN)2^–]anion.This strategy enables HCl to accept electrons from[N(CN)2^–]anions in Au–[N(CN)2^–]complexes rather than from pure[Bmim][N(CN)2],leading to notable improvement in both the reaction path and the stability of the catalyst without changing the reaction triggered by acetylene adsorption.Furthermore,the induction period of the Au–SILP catalyst was shown to be absent in the reaction process due to the high Au(III)content in the Au(Ⅲ)/Au(Ⅰ)site and the high substrate diffusion rate in the ionic liquid layer.This work provides a facile method to improve the stability of Au-based catalysts for acetylene hydrochlorination.
基金The National Natural Science Foundation of China(No.41572276)the National Key Research and Development Program of China(No.2017YFC0805400)
文摘In order to obtain the seismic responses of the soil-rectangular tunnel structure,based on the PL-Finn constitutive model,four different conditions,namely,the liquefied soil around the rectangular tunnel,the liquefied soil below the rectangular tunnel,the liquefied soil on either side of the tunnel and the structure on non-liquefied soil,are compared.In accordance to the time at which a large deformation occurs,the possibility of destruction from hard to easy follows a descending order:the liquefied soil all around the structure,the liquefied soil on the bottom of the structure,and the liquefied soil on the two sides of the structure.The area of large deformation is mostly beneath the two arch angles of the tunnel floor.The soil on the two sides,especially close to the structure,is the hardest to liquefy and deform.The large deformation of soil caused by the liquefaction appears after the peak seismic value occurs.The higher the input seismic value is,the easier a large deformation can take place.With the same input of peak ground motion,the total displacement vector of the structure and differential displacement of the side-wall are in accordance with an order from large to small in the three situations:when the saturated sand is on two sides,all around the structure,and on the bottom of the structure.
基金National Key Research and Development Program of China,Grant/Award Number:2019YFA0705400The Fundamental Research Funds for the Central Universities,Grant/Award Number:NJ202202+1 种基金The Research Fund of State Key Laboratory of Mechanics and Control of Mechanical Structures,Grant/Award Number:MCMS-I-0421K01Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20212008。
文摘Water constitutes the largest energy carrier on earth,absorbing more than 70%of the solar energy received by the earth's surface,yet its low exploitation has been a constant concern.The hydrovoltaic effect is an emerging technology that generates electricity through the direct interaction between nanomaterials and water of various forms(raindrops,waves,flows,moisture,and natural evaporation).Especially,the evaporation-driven hydrovoltaic effect is a spontaneous and ubiquitous process that can directly convert thermal energy from the surrounding environment into electricity without the demand for additional mechanical work,which shows unique advantages compared with other hydrovoltaic effects.A variety of nanostructured materials have been steadily developed for evaporation-driven hydrovoltaic devices(EHDs)in recent years.However,there has been a lack of a clear specification on the selection and design of materials for improving device performance.Herein,we first analyze the mechanisms of EHDs followed by a summarization of the recent advances in materials,including carbon materials,biomass-based materials,metal oxides,composite materials,and others.We then discuss the strategies for improving the energy conversion efficiency and the output power in terms of structural design,surface modification,and interface treatment.Finally,we provide an outlook on the potential applications of electricity generation,sensors,and desalination technology,as well as the challenges and prospects for the development of this emerging technology in the future.
基金National Natural Science Foundation of China(Nos.52271107,and 51701218)Natural Science Foundation of Shandong Province(No.ZR2021ME241)+1 种基金Natural Science Foundation of Liaoning Province(No.2020-MS-004)Bintech-IMR R&D Program(GYY-JSBU-2022-012).
文摘The effect of precipitation aging on the fracture behavior of cast Mg-14.23Gd-0.45Zr(wt.%)alloy at room temperature has been studied in this work.Uniaxial tensile and three-point bending tests were conducted on samples peak-aged at 175,200,225,and 250 ℃.Notably,samples aged at 175 ℃ and 200 ℃ exhibited premature fracture during the uniaxial tensile test.Through fractographic observations of the tensile test samples and electron backscattered diffraction(EBSD)analysis on the samples sub-jected to three-point bending tests,a preferential formation of cleavage cracks in samples aged at 175 ℃ and 200 ℃ was identified as the reason for their premature fracture.The X-ray diffraction(XRD)results and transmission electron microscopy(TEM)observations of precipitates indicate that the dominant strengthening precipitates in all peak-aged samples are of theβ'phase,and their size significantly influences the formation of cleavage cracks.This phenomenon is attributed to the shearing mechanism of precipitates.Specifically,the smaller β'precipitates formed under the aging temperature of 175-200 ℃ are susceptible to dislocation shearing,leading to the formation of cleavage cracks.In contrast,the larger size of β'precipitates formed under the aging temperature of 225-250 ℃ provides resistance to shearing,resulting in the restrained formation of cleavage cracks and ultimately contributing to the enhancement of the ultimate tensile strength.
基金Financial support from the National Natural Science Foundation of China (NSFCgrant No.U20A20119,21606199,22078302,52070035)+3 种基金the Science and Technology Department of Zhejiang Province (LGG20B060004)the China Postdoctoral Science Foundation (2020M671791)the Jilin Province Scientific and the Technological Planning Project of China (No.20200403001SF)the National Key Research and Development Program of China (2021YFA1501800,2021YFA1501801,2021YFA1501802)。
文摘Rational design of catalytic sites to activate the C≡C bond is of paramount importance to advance acetylene hydrochlorination. Herein, Cu sites with electron-rich and electron-deficient states were constructed by controlling the impregnation solutions. The π electrons flowing from acetylene to Cu site are facilitated over the electron-deficient Cu sites, achieving high activation of C≡C bond. The contradiction between the increased activation of acetylene required for enhanced catalytic activity and the resistance of Cu site to reduction by acetylene required for maintaining catalytic stability can be balanced by establishing strong interactions of Cu site with pyrrolic-N species. The catalytic activity displays a volcano shape scaling relationship as a function of Cu particle size. Tribasic copper chloride is concomitantly generated with the construction of electron-deficient Cu sites. The H–Cl bond of HCl can be activated over the tribasic copper chloride, accelerating the surface reaction of vinyl chloride production. This strategy of inducing electron deficiency provides new insight into the rational design of catalysts for the synthesis of vinyl chloride with a high catalytic performance.
基金supported by National Natural Science Foundation of China(11771257)the Shandong Provincial Natural Science Foundation of China(ZR2023YQ002,ZR2023MA007,ZR2021MA004)。
文摘For singularly perturbed convection-diffusion problems,supercloseness analysis of the finite element method is still open on Bakhvalov-type meshes,especially in the case of 2D.The difficulties arise from the width of the mesh in the layer adjacent to the transition point,resulting in a suboptimal estimate for convergence.Existing analysis techniques cannot handle these difficulties well.To fill this gap,here a novel interpolation is designed delicately for the smooth part of the solution,bringing about the optimal supercloseness result of almost order 2 under an energy norm for the finite element method.Our theoretical result is uniform in the singular perturbation parameterεand is supported by the numerical experiments.
