Methacrylyloxypropyl modified inorganic/organic hybrid mesoporous materials have been synthesized via an HCl catalyzed sol gel process in the presence of citric acid (CA) as a nonsurfactant template, which involves a ...Methacrylyloxypropyl modified inorganic/organic hybrid mesoporous materials have been synthesized via an HCl catalyzed sol gel process in the presence of citric acid (CA) as a nonsurfactant template, which involves a combination of 3 (trimethoxysilyl)propyl methacrylate (MSMA) and tetraethoxysilane (TEOS) as precursor species.The CA nonsurfactant is removed by extraction with water, resulting in inorganic/organic hybrid mesoporous materials with high surface area (e.g. 900?m 2·g -1 ) and large pore volume (e.g. 0 55?cm 3·g -1 ).The surface area, pore volume and pore diameter increase slightly with increasing the content of CA.The products were characterized by XRD, N 2 adsorption desorption and FT IR.展开更多
文摘Methacrylyloxypropyl modified inorganic/organic hybrid mesoporous materials have been synthesized via an HCl catalyzed sol gel process in the presence of citric acid (CA) as a nonsurfactant template, which involves a combination of 3 (trimethoxysilyl)propyl methacrylate (MSMA) and tetraethoxysilane (TEOS) as precursor species.The CA nonsurfactant is removed by extraction with water, resulting in inorganic/organic hybrid mesoporous materials with high surface area (e.g. 900?m 2·g -1 ) and large pore volume (e.g. 0 55?cm 3·g -1 ).The surface area, pore volume and pore diameter increase slightly with increasing the content of CA.The products were characterized by XRD, N 2 adsorption desorption and FT IR.
文摘目的 研究运动想象-动觉治疗对缺血性卒中患者偏瘫侧手功能的康复效果,探索对缺血性卒中患者有效的手功能训练方法。方法 前瞻性入组2021年1月-2022年1月在首都医科大学附属北京天坛医院康复科住院及门诊诊疗的发病1个月内的缺血性卒中患者,将患者随机分为研究组(运动想象-动觉治疗组)和对照组(常规康复组)。研究组每日分别进行1次运动想象-动觉治疗和1次常规康复,治疗时间均为30 min,每周5 d,持续4周。对照组每日进行2次常规康复,每次治疗时间为30 min,每周5 d,持续4周。在治疗前对患者采用MoCA评定认知功能,采用混乱运动想象评估(chaotic motor imagery assessment battery,CMIA)和运动觉及视觉想象问卷(kinesthetic and visual imagery questionnaire,KVIQ)评定患者的运动想象能力,采用汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评定患者是否存在抑郁。在治疗前、治疗4周后对患者进行Fugl-Meyer运动量表上肢部分(Fugl-Meyer assessment-upper extremity,FMA-UE)、Wolf上肢运动量表(Wolf motor function test,WMFT)、手臂动作调查测试(action research arm test,ARAT)进行手运动功能评定,采用日常生活能力(activity of daily living,ADL)量表评定日常生活能力,比较患者治疗前后上述指标的差异。结果 研究共入组67例患者,对照组33例,脱落1例,研究组34例,脱落3例。两组基线数据差异无统计学意义。在治疗4周后,研究组的FMA-UE量表[50(40~58)分vs. 37(24~56)分,P=0.017]、WMFT量表评分等级[53(41~64)分vs. 42(32~57)分,P=0.013]、ARAT量表[45(35~50)分vs. 35(16~48)分,P=0.005]、ADL量表[80(70~85)分vs. 65(60~85)分,P=0.008]均高于对照组,但WMFT上肢运动量表中的作业时间差异无统计学意义。结论 运动想象-动觉疗法与常规康复相比,可明显改善缺血性卒中患者偏瘫侧的手功能及日常生活能力。
