恶性中心气道狭窄(malignant central airway obstruction,MCAO)是指因原发或转移的恶性肿瘤侵及气管、隆突、左右主支气管或右中间支气管引起的管腔狭窄[1];患者会出现不同程度的呼吸困难,严重者可导致窒息、甚至危及生命。按照中心气...恶性中心气道狭窄(malignant central airway obstruction,MCAO)是指因原发或转移的恶性肿瘤侵及气管、隆突、左右主支气管或右中间支气管引起的管腔狭窄[1];患者会出现不同程度的呼吸困难,严重者可导致窒息、甚至危及生命。按照中心气道病变位置将MCAO分为管内型、管壁型、管外型和混合型[2]。管外型和混合型MCAO的瘤体组织可向管腔外生长并侵及纵隔结构;由于上腔静脉具有管壁薄、内部血流压力低的特点,因此一旦上纵隔受到肿瘤侵犯,就容易导致上腔静脉受压,出现头痛、头晕、颜面部水肿和呼吸困难等上腔静脉综合征(superior vena cava syndrome,SVCS)表现。对于MCAO,支气管镜下气道消瘤和/或气道支架置入术可以快速缓解呼吸困难[3,4];对于恶性肿瘤所致SVCS则可通过血管腔内支架置入术来缓解症状[5]。然而,晚期肺癌同时侵及中心气道和上腔静脉导致MCAO合并SVCS的病例罕见报道,其治疗方法亦无统一共识。现报道我科气道支架和上腔静脉支架联合置入治疗晚期非小细胞肺癌导致中心气道狭窄和上腔静脉综合征1例,效果满意,以供临床借鉴。展开更多
Chinese medicine is a healing medicine which respect the power of human body itself. The essentials of Chinese medicine is promoting health wellness instead of disease management. Modern medicine just realized the lim...Chinese medicine is a healing medicine which respect the power of human body itself. The essentials of Chinese medicine is promoting health wellness instead of disease management. Modern medicine just realized the limits of its theory. P4 medicine (personalized, predictive, preventive, and participatory/precision) similar to Chinese medicine theory is beginning to representing the pioneer in the Western world. In this review, we summarized different domains of Chinese medicine. Based on the basic of promoting health wellness, we compared the fundamental theory of Chinese medicine to the new merging P4 medicine idea of Western medicine. We also discussed the potential for using modern computational medicine technique to integrate Chinese medicine theory and Western medicine theory.展开更多
文摘Chinese medicine is a healing medicine which respect the power of human body itself. The essentials of Chinese medicine is promoting health wellness instead of disease management. Modern medicine just realized the limits of its theory. P4 medicine (personalized, predictive, preventive, and participatory/precision) similar to Chinese medicine theory is beginning to representing the pioneer in the Western world. In this review, we summarized different domains of Chinese medicine. Based on the basic of promoting health wellness, we compared the fundamental theory of Chinese medicine to the new merging P4 medicine idea of Western medicine. We also discussed the potential for using modern computational medicine technique to integrate Chinese medicine theory and Western medicine theory.