摘要
肺肉瘤样癌(pulmonary sarcomatoid carcinoma,PSC)是一类罕见的、恶性程度较高的肺部肿瘤,分为多形性癌、梭形细胞癌、巨细胞癌、癌肉瘤和肺母细胞瘤5种病理类型。PSC发病隐匿,临床症状和体征无特异性,与肿瘤生长和侵袭部位密切相关,可表现为刺激性咳嗽、痰中带血丝、呼吸困难或胸痛等。PSC易早期出现转移,多数患者就诊时已是局部进展期或晚期,中位生存时间为9个月。我呼吸病中心诊治1例致中央气道狭窄90%的原发性PSC患者;通过血管介入和气管镜下介入联合治疗的方法拯救了患者生命,延长了生存时间,术后随访19个月,效果满意,现报道如下,以供临床借鉴。
Pulmonary sarcomatoid carcinoma(PSC)is a rare and highly malignant tumor,which includes the following five pathologic types:pleomorphic carcinoma,spindle cell carcinoma,giant cell carcinoma,carcinosarcoma and pulmonary blastoma.The onset of PSC is occult with non-specific clinical symptoms and signs.The clinical manifestations include irritating cough,bloody sputum,dyspnea,chest pain and so on,which are closely related to the growth and invasion site of the tumor.PSC tends to metastasize early,so most patients are already in local advanced stage or advanced stage with a median survival of 9 months at the time of hospital visit.A patient with primary PSC which led to 90%stenosis in central airway was treated by combined method of vascular and tracheoscopic intervention in our respiratory center.This treatment prolonged the patient’s survival time and got a satisfactory effect at 19-month follow-up after surgery.Herein we report the case for clinical reference.
作者
霍小森
邹珩
董延妍
李媛
边灵杰
李磊
王洪武
Xiaosen HUO;Hang ZOU;Yanyan DONG;Yuan LI;Lingjie BIAN;Lei LI;Hongwu WANG(Respiratory Disease Center,Dongzhimen Hospital of Beijing University of Chinese Medicine,Beijing 101121,China)
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2024年第2期157-160,共4页
Chinese Journal of Lung Cancer
基金
北京中医药大学基本科研业务费项目(No.2023-JYB-XJSJJ-040)资助。
关键词
肺肉瘤样癌
肺肿瘤
中央气道狭窄
Pulmonary sarcomatoid carcinoma
Lung neoplasms
Central airway stenosis
