目的探讨动态血糖监测指导个体化营养与运动联合治疗妊娠期糖尿病的效果,为妊娠期糖尿病的疗效提供评价系统。方法选取我院收治的96例妊娠期糖尿病孕妇,根据随机数字表法将孕妇平均分为观察组和对照组,每组48例。对照组孕妇给予常规妊...目的探讨动态血糖监测指导个体化营养与运动联合治疗妊娠期糖尿病的效果,为妊娠期糖尿病的疗效提供评价系统。方法选取我院收治的96例妊娠期糖尿病孕妇,根据随机数字表法将孕妇平均分为观察组和对照组,每组48例。对照组孕妇给予常规妊娠糖尿病营养指导和适量运动,观察组孕妇根据血糖水平给予个体化营养与运动的联合治疗,比较2组孕妇治疗前、后血糖和血脂水平,并观察孕妇和新生儿出生体质量和妊娠结局。结果治疗前2组妊娠期糖尿病孕妇生化指标、空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(HbA1C)、三酰甘油(TG)和总胆固醇(TC)比较差异无统计学差异(P>0.05)。经联合治疗后观察组妊娠期糖尿病孕妇生化指标(FBG、2 hPBG、HbA1C、TG和TC)显著低于治疗后对照组,差异存在统计学意义(P<0.05)。联合治疗后观察组妊娠期糖尿病孕妇孕期总增重、每周增重、孕期体质量指数(BMI)增加和每周BMI增加以及新生儿出生体质量均明显低于治疗后对照组,同时观察组孕妇子痫前期、早产、羊水过多、巨大儿、剖宫产和产后出血比例均明显低于对照组,差异存在统计学意义(P<0.05)。结论动态血糖监测指导的个体化营养与运动的联合治疗能够降低妊娠期糖尿病孕妇血糖、血脂水平,改善孕妇和胎儿体质量,降低不良妊娠结局的产生,为妊娠糖尿病的综合治疗提供参考。展开更多
Objective: To find out the optimal approach to decompress externally the severe injured brain and to avoid possible complications caused by external decompression. Methods: 68 patients who underwent external decompres...Objective: To find out the optimal approach to decompress externally the severe injured brain and to avoid possible complications caused by external decompression. Methods: 68 patients who underwent external decompression after traumatic brain injury were admitted into Tianjin Medical University General Hospital for cranioplasty from 1995 to 2001. Complications were retrospectively investigated and analyzed in all patients. The findings were compared between the patients who accepted the decompressive craniectomy in our hospital and in local hospitals. χ 2-test was employed for statistical analysis and complication evaluation. Results: Large craniectomy definitely caused some side effects to patients. Among various complications, several of them showed significantly high incidence (P< 0.05) in patients who underwent the decompressive operation in local hospitals such as shunt-dependent hydrocephalous, subdural fluid collection, and CSF leakage from scalp incision. The rest of the complications had no remarkable difference (P> 0.05) between the two groups including dilation or/and migration of lateral ventricle underlying the cranial defect, skin flap concavity, encephalomalacia of the decompressive area, seizure and infection. Conclusions: To reduce the incidence of iatrogenic side effects, surgical craniectomy should be performed according to the strict indication and standard and any abuse should be avoided.展开更多
文摘目的探讨动态血糖监测指导个体化营养与运动联合治疗妊娠期糖尿病的效果,为妊娠期糖尿病的疗效提供评价系统。方法选取我院收治的96例妊娠期糖尿病孕妇,根据随机数字表法将孕妇平均分为观察组和对照组,每组48例。对照组孕妇给予常规妊娠糖尿病营养指导和适量运动,观察组孕妇根据血糖水平给予个体化营养与运动的联合治疗,比较2组孕妇治疗前、后血糖和血脂水平,并观察孕妇和新生儿出生体质量和妊娠结局。结果治疗前2组妊娠期糖尿病孕妇生化指标、空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(HbA1C)、三酰甘油(TG)和总胆固醇(TC)比较差异无统计学差异(P>0.05)。经联合治疗后观察组妊娠期糖尿病孕妇生化指标(FBG、2 hPBG、HbA1C、TG和TC)显著低于治疗后对照组,差异存在统计学意义(P<0.05)。联合治疗后观察组妊娠期糖尿病孕妇孕期总增重、每周增重、孕期体质量指数(BMI)增加和每周BMI增加以及新生儿出生体质量均明显低于治疗后对照组,同时观察组孕妇子痫前期、早产、羊水过多、巨大儿、剖宫产和产后出血比例均明显低于对照组,差异存在统计学意义(P<0.05)。结论动态血糖监测指导的个体化营养与运动的联合治疗能够降低妊娠期糖尿病孕妇血糖、血脂水平,改善孕妇和胎儿体质量,降低不良妊娠结局的产生,为妊娠糖尿病的综合治疗提供参考。
文摘Objective: To find out the optimal approach to decompress externally the severe injured brain and to avoid possible complications caused by external decompression. Methods: 68 patients who underwent external decompression after traumatic brain injury were admitted into Tianjin Medical University General Hospital for cranioplasty from 1995 to 2001. Complications were retrospectively investigated and analyzed in all patients. The findings were compared between the patients who accepted the decompressive craniectomy in our hospital and in local hospitals. χ 2-test was employed for statistical analysis and complication evaluation. Results: Large craniectomy definitely caused some side effects to patients. Among various complications, several of them showed significantly high incidence (P< 0.05) in patients who underwent the decompressive operation in local hospitals such as shunt-dependent hydrocephalous, subdural fluid collection, and CSF leakage from scalp incision. The rest of the complications had no remarkable difference (P> 0.05) between the two groups including dilation or/and migration of lateral ventricle underlying the cranial defect, skin flap concavity, encephalomalacia of the decompressive area, seizure and infection. Conclusions: To reduce the incidence of iatrogenic side effects, surgical craniectomy should be performed according to the strict indication and standard and any abuse should be avoided.
