Objective: To study the clinical efficacy of electroacupuncture (EA) on treating knee osteoarthritis (KOA) of Shen (肾)-Sui ((肾) insufficiency (SSI) syndrome type. Methods: A total of 245 patients (279 ...Objective: To study the clinical efficacy of electroacupuncture (EA) on treating knee osteoarthritis (KOA) of Shen (肾)-Sui ((肾) insufficiency (SSI) syndrome type. Methods: A total of 245 patients (279 knees) of KOA-SSI were randomly assigned to two groups by lottery: 141 knees in the treatment group and 138 knees in the control group. The treatment group was managed with EA at the dominant points of Neixiyan (Ex-LE4) and Waixiyan (Ex-LE5) as well as the conjugate points of Xuanzhong (GB39) and Taixi (KI3) for 30 min, once a day, with 15 days as one course; 2 courses were applied with a 5-day interval in between. The control group was treated with intra-articular injection of 2 mL hyaluronic acid into the affected joint every 7 days for 5 times in total. The clinical effects on the patients in different stages were observed, and their symptom scores of knee and contents of cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor- α (TNF- α), prostaglandin E2, (PGE2α) and matrix metalloproteinases-3 (MMP-3), in the knee joint fluid were measured before and after treatment. Results: The study was completed in 235 patients (263 knees); four patients (7 knees) in the treatment group and six patients (9 knees) in the control group dropped out. Comparison of therapeutic effects (excellent and effective rates) between the two groups showed insignificant differences (P〉0.05). Symptom scores of knee and contents of cytokines in the knee fluid after treatment were lowered significantly in the patients of stage Ⅰ -Ⅲ in both groups (P〈0.05 or P〈0.01). However, the lowering of the total symptom score of knee in the patients of stage Ⅲ in the treatment group was more significant (P〈0.05). Conclusions: EA could effectively alleviate the clinical symptoms in KOA patients of stage m, showing an effect superior to that of hyaluronic acid. EA also shows action in suppressing the secre展开更多
为提高陕西省关中平原冬小麦的估产精度,该文通过粒子滤波算法同化Landsat遥感数据反演的状态量叶面积指数(leaf area index,LAI)、土壤含水量(0~20 cm)、地上干生物量数据和CERES-Wheat模型模拟的状态量数据,分析小麦不同生育期的LAI...为提高陕西省关中平原冬小麦的估产精度,该文通过粒子滤波算法同化Landsat遥感数据反演的状态量叶面积指数(leaf area index,LAI)、土壤含水量(0~20 cm)、地上干生物量数据和CERES-Wheat模型模拟的状态量数据,分析小麦不同生育期的LAI、土壤含水量及生物量同化值和实测单产的线性相关性,以构建同化估产模型。结果表明,在返青期土壤含水量同化值和实测单产的相关性高于LAI、生物量同化值和实测单产的相关性,选择土壤含水量作为最优变量;在拔节期和抽穗-灌浆期同时选择LAI、土壤含水量及生物量作为最优变量;在乳熟期选择生物量作为最优变量。在小麦各生育时期同化最优变量的估产精度(R2=0.85)高于同时同化LAI、土壤含水量及生物量的估产精度,同时同化LAI、土壤含水量及生物量的估产精度高于同时同化LAI和土壤含水量(或LAI和地上干生物量、或土壤含水量和地上干生物量)的估产精度,表明在作物不同生育时期同化与产量相关性较大的变量对提高估产精度有重要作用。展开更多
基金Supported by the National Natural Science Foundation of China (No.30873277)the CHEN Ke-ji Development Fund of Integrative Medicine(No.CKJ2008003)
文摘Objective: To study the clinical efficacy of electroacupuncture (EA) on treating knee osteoarthritis (KOA) of Shen (肾)-Sui ((肾) insufficiency (SSI) syndrome type. Methods: A total of 245 patients (279 knees) of KOA-SSI were randomly assigned to two groups by lottery: 141 knees in the treatment group and 138 knees in the control group. The treatment group was managed with EA at the dominant points of Neixiyan (Ex-LE4) and Waixiyan (Ex-LE5) as well as the conjugate points of Xuanzhong (GB39) and Taixi (KI3) for 30 min, once a day, with 15 days as one course; 2 courses were applied with a 5-day interval in between. The control group was treated with intra-articular injection of 2 mL hyaluronic acid into the affected joint every 7 days for 5 times in total. The clinical effects on the patients in different stages were observed, and their symptom scores of knee and contents of cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor- α (TNF- α), prostaglandin E2, (PGE2α) and matrix metalloproteinases-3 (MMP-3), in the knee joint fluid were measured before and after treatment. Results: The study was completed in 235 patients (263 knees); four patients (7 knees) in the treatment group and six patients (9 knees) in the control group dropped out. Comparison of therapeutic effects (excellent and effective rates) between the two groups showed insignificant differences (P〉0.05). Symptom scores of knee and contents of cytokines in the knee fluid after treatment were lowered significantly in the patients of stage Ⅰ -Ⅲ in both groups (P〈0.05 or P〈0.01). However, the lowering of the total symptom score of knee in the patients of stage Ⅲ in the treatment group was more significant (P〈0.05). Conclusions: EA could effectively alleviate the clinical symptoms in KOA patients of stage m, showing an effect superior to that of hyaluronic acid. EA also shows action in suppressing the secre
文摘为提高陕西省关中平原冬小麦的估产精度,该文通过粒子滤波算法同化Landsat遥感数据反演的状态量叶面积指数(leaf area index,LAI)、土壤含水量(0~20 cm)、地上干生物量数据和CERES-Wheat模型模拟的状态量数据,分析小麦不同生育期的LAI、土壤含水量及生物量同化值和实测单产的线性相关性,以构建同化估产模型。结果表明,在返青期土壤含水量同化值和实测单产的相关性高于LAI、生物量同化值和实测单产的相关性,选择土壤含水量作为最优变量;在拔节期和抽穗-灌浆期同时选择LAI、土壤含水量及生物量作为最优变量;在乳熟期选择生物量作为最优变量。在小麦各生育时期同化最优变量的估产精度(R2=0.85)高于同时同化LAI、土壤含水量及生物量的估产精度,同时同化LAI、土壤含水量及生物量的估产精度高于同时同化LAI和土壤含水量(或LAI和地上干生物量、或土壤含水量和地上干生物量)的估产精度,表明在作物不同生育时期同化与产量相关性较大的变量对提高估产精度有重要作用。