To investigate the evaluation value of intravoxel incoherent motion diffusion-weighted imaging(IVIM-DWI)on the early efficacy of magnetic resonance-guided high-intensity focused ultrasound(MRgFUS)ablation for uterine ...To investigate the evaluation value of intravoxel incoherent motion diffusion-weighted imaging(IVIM-DWI)on the early efficacy of magnetic resonance-guided high-intensity focused ultrasound(MRgFUS)ablation for uterine adenomyoma.The clinical and magnetic resonance imaging(MRI)data of 36 patients with uterine adenomyoma before and after MRgFUS treatment in our hospital from January 2018 to December 2018 were retrospectively analyzed.All the 36 patients underwent MRI examination one day before operation and immediately after operation using GE Discovery MR7503.0T MRI,including conventional sequences(T1WI,T2WI,and T2 fat suppression sequences)plain scan,IVIM-DWI sequences with 9 b values,and contrast enhanced-MRI sequences.The IVIM-DWI quantitative parameters(true diffusion coefficient D,perfusion related diffusion coefficient D*,and perfusion fraction f)of double-exponential model were obtained by using GE ADW 4.7 functool,a postprocessor.SPSS 24.0 software was used to analyze the difference in parameter between the ablation and non-ablation areas of uterine adenomyoma.DWI signal in the ablation area of uterine adenomyoma was increased,and manifested as heterogeneous diffuse high signal,with low central signal and high edge signal.Values of D,D*and f in the ablation area of uterine adenomyoma were significantly lower than those in the non-ablation area,and there was statistical difference between the two(P<0.05).The areas under receiver operating characteristic(ROC)curve of D,D*and f values in the ablation area of uterine adenomyoma were 0.854,0.898 and 0.924,respectively;the optimal thresholds for the diagnosis of ablation area of uterine adenomyoma were 0.81×10−3 mm2/s,4.99×10−3 mm2/s and 0.24,respectively;the diagnostic sensitivity was 80.6%,72.2%and 94.4%,respectively;and the specificity was 91.7%,97.2%and 94.4%,respectively.IVIM-DWI has a certain clinical value in the evaluation on early efficacy of MRgFUS ablation of uterine adenomyosis.展开更多
目的比较全数字化钼靶(FFDM)与MRI动态增强(MRI-DCE)检查在乳腺肿瘤良、恶性鉴别中的临床价值。方法回顾性分析经病理证实的37例乳腺肿瘤,其中恶性22例,良性15例,所有病例均行FFDM和MRI-DCE检查,在GEADW4.3工作站进行后处理,观察X线表...目的比较全数字化钼靶(FFDM)与MRI动态增强(MRI-DCE)检查在乳腺肿瘤良、恶性鉴别中的临床价值。方法回顾性分析经病理证实的37例乳腺肿瘤,其中恶性22例,良性15例,所有病例均行FFDM和MRI-DCE检查,在GEADW4.3工作站进行后处理,观察X线表现、动态增强表现,绘制时间-信号强度曲线(time-intensity curves,TIC),分别计算良、恶性肿瘤的早期强化率,根据美国放射学会乳腺影像报告和数据系统(breast imaging reporting and data system,BI-RADS)进行定级,3级及以下的级别考虑为良性,4A级及以上的为恶性,与病理结果对照,分别计算各自的敏感性、特异性、准确性。结果 FFDM和MRI-DCE的敏感性、特异性、准确性各依次为80.00%、79.17%、79.48%;88.23%、90.91%、89.74%。两者特异性有显著性差异(P<0.05),两者确诊的病例部分互为补充。结论在FFDM的基础上,选择性的对可疑病变行MRI-DCE检查,可以提高良、恶性鉴别诊断的准确性,从而降低手术活检的几率,提高患者的生存质量。展开更多
文摘To investigate the evaluation value of intravoxel incoherent motion diffusion-weighted imaging(IVIM-DWI)on the early efficacy of magnetic resonance-guided high-intensity focused ultrasound(MRgFUS)ablation for uterine adenomyoma.The clinical and magnetic resonance imaging(MRI)data of 36 patients with uterine adenomyoma before and after MRgFUS treatment in our hospital from January 2018 to December 2018 were retrospectively analyzed.All the 36 patients underwent MRI examination one day before operation and immediately after operation using GE Discovery MR7503.0T MRI,including conventional sequences(T1WI,T2WI,and T2 fat suppression sequences)plain scan,IVIM-DWI sequences with 9 b values,and contrast enhanced-MRI sequences.The IVIM-DWI quantitative parameters(true diffusion coefficient D,perfusion related diffusion coefficient D*,and perfusion fraction f)of double-exponential model were obtained by using GE ADW 4.7 functool,a postprocessor.SPSS 24.0 software was used to analyze the difference in parameter between the ablation and non-ablation areas of uterine adenomyoma.DWI signal in the ablation area of uterine adenomyoma was increased,and manifested as heterogeneous diffuse high signal,with low central signal and high edge signal.Values of D,D*and f in the ablation area of uterine adenomyoma were significantly lower than those in the non-ablation area,and there was statistical difference between the two(P<0.05).The areas under receiver operating characteristic(ROC)curve of D,D*and f values in the ablation area of uterine adenomyoma were 0.854,0.898 and 0.924,respectively;the optimal thresholds for the diagnosis of ablation area of uterine adenomyoma were 0.81×10−3 mm2/s,4.99×10−3 mm2/s and 0.24,respectively;the diagnostic sensitivity was 80.6%,72.2%and 94.4%,respectively;and the specificity was 91.7%,97.2%and 94.4%,respectively.IVIM-DWI has a certain clinical value in the evaluation on early efficacy of MRgFUS ablation of uterine adenomyosis.
文摘目的比较全数字化钼靶(FFDM)与MRI动态增强(MRI-DCE)检查在乳腺肿瘤良、恶性鉴别中的临床价值。方法回顾性分析经病理证实的37例乳腺肿瘤,其中恶性22例,良性15例,所有病例均行FFDM和MRI-DCE检查,在GEADW4.3工作站进行后处理,观察X线表现、动态增强表现,绘制时间-信号强度曲线(time-intensity curves,TIC),分别计算良、恶性肿瘤的早期强化率,根据美国放射学会乳腺影像报告和数据系统(breast imaging reporting and data system,BI-RADS)进行定级,3级及以下的级别考虑为良性,4A级及以上的为恶性,与病理结果对照,分别计算各自的敏感性、特异性、准确性。结果 FFDM和MRI-DCE的敏感性、特异性、准确性各依次为80.00%、79.17%、79.48%;88.23%、90.91%、89.74%。两者特异性有显著性差异(P<0.05),两者确诊的病例部分互为补充。结论在FFDM的基础上,选择性的对可疑病变行MRI-DCE检查,可以提高良、恶性鉴别诊断的准确性,从而降低手术活检的几率,提高患者的生存质量。
