Two series of cationic polyacrylamide of quaternary pyridine salt-type were synthesized, which have different cationic degrees and molecular weights respectively. The antibacterial property of QPAV was investigated, t...Two series of cationic polyacrylamide of quaternary pyridine salt-type were synthesized, which have different cationic degrees and molecular weights respectively. The antibacterial property of QPAV was investigated, the influence of various factors on the antibacterial property was examined by using E. Coli as the disease-leading bacterium and the method of plate counting live bacterium. The antibacterial mechanism of QPAV was studied by using the method of measuring the activity of β-D-galactosidase. The experiment results show that QPAV possesses an excellent antibacterial property. The higher the cationic degree of QPAV is, the stronger the antibacterial property is. In certain range of molecular weight, the higher molecular weight of QPAV is, the better the antibacterial effect is. The pH value also influences the antibacterial property of QPAV. The antibacterial effect of QPAV is based on sterilization action certainly and is not only a restraining action.展开更多
以α-溴乙苯为引发剂,溴化亚铜为催化剂,2,2′-联吡啶为配体,二甲苯为溶剂,采用开放的溶液聚合体系,在磁力搅拌与氮气保护下,用原子转移自由基聚合ATRP(A tom T ransfer R ad ica lPo lym erization)法合成了嵌段共聚物聚苯乙烯-b-聚丙...以α-溴乙苯为引发剂,溴化亚铜为催化剂,2,2′-联吡啶为配体,二甲苯为溶剂,采用开放的溶液聚合体系,在磁力搅拌与氮气保护下,用原子转移自由基聚合ATRP(A tom T ransfer R ad ica lPo lym erization)法合成了嵌段共聚物聚苯乙烯-b-聚丙烯酸丁酯(PS t-b-PBA);用FT IR,1H-NM R,GPC等手段对活性聚合进行了确认,对嵌段共聚物进行了表征;水解PS t-b-PBA制备了两亲性嵌段共聚物苯乙烯-b-聚丙烯酸(PS t-b-PAA);采用直接溶解法配制了PS t-b-PAA在甲苯中的反胶束溶液;利用透射电镜(TEM)观察有效地考察了两亲嵌段共聚物PS t-b-PAA在甲苯溶液中的自组装行为.研究结果表明,在开放体系下也能较好地实施原子转移自由基聚合,制得窄分布的嵌段共聚物;控制两嵌段的长度可制得亲水链PAA短的两亲嵌段共聚物PS t-b-PAA,使其在甲苯中发生自组装,形成以亲水段为核,疏水段为壳的反胶束结构.展开更多
文摘Two series of cationic polyacrylamide of quaternary pyridine salt-type were synthesized, which have different cationic degrees and molecular weights respectively. The antibacterial property of QPAV was investigated, the influence of various factors on the antibacterial property was examined by using E. Coli as the disease-leading bacterium and the method of plate counting live bacterium. The antibacterial mechanism of QPAV was studied by using the method of measuring the activity of β-D-galactosidase. The experiment results show that QPAV possesses an excellent antibacterial property. The higher the cationic degree of QPAV is, the stronger the antibacterial property is. In certain range of molecular weight, the higher molecular weight of QPAV is, the better the antibacterial effect is. The pH value also influences the antibacterial property of QPAV. The antibacterial effect of QPAV is based on sterilization action certainly and is not only a restraining action.
文摘以α-溴乙苯为引发剂,溴化亚铜为催化剂,2,2′-联吡啶为配体,二甲苯为溶剂,采用开放的溶液聚合体系,在磁力搅拌与氮气保护下,用原子转移自由基聚合ATRP(A tom T ransfer R ad ica lPo lym erization)法合成了嵌段共聚物聚苯乙烯-b-聚丙烯酸丁酯(PS t-b-PBA);用FT IR,1H-NM R,GPC等手段对活性聚合进行了确认,对嵌段共聚物进行了表征;水解PS t-b-PBA制备了两亲性嵌段共聚物苯乙烯-b-聚丙烯酸(PS t-b-PAA);采用直接溶解法配制了PS t-b-PAA在甲苯中的反胶束溶液;利用透射电镜(TEM)观察有效地考察了两亲嵌段共聚物PS t-b-PAA在甲苯溶液中的自组装行为.研究结果表明,在开放体系下也能较好地实施原子转移自由基聚合,制得窄分布的嵌段共聚物;控制两嵌段的长度可制得亲水链PAA短的两亲嵌段共聚物PS t-b-PAA,使其在甲苯中发生自组装,形成以亲水段为核,疏水段为壳的反胶束结构.