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Cosmetic outcome and surgical site infection rates of antibacterial absorbable (Polyglactin 910) suture compared to Chinese silk suture in breast cancer surgery: a randomized pilot research 被引量:9
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作者 ZHANG Zhong-tao ZHANG Hong-wei +8 位作者 FANG Xue-dong WANG Li-ming LI Xiao-xi LI Ya-fen SUN Xiao-wei Judith Carver Dorella Simpkins Jessica Shen Martin Weisberg 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第5期719-724,共6页
Background The primary objective of this multicenter post-market study was to compare the cosmetic outcome of triclosan-coated VICRYL* Plus sutures with Chinese silk sutures for skin closure of modified radical maste... Background The primary objective of this multicenter post-market study was to compare the cosmetic outcome of triclosan-coated VICRYL* Plus sutures with Chinese silk sutures for skin closure of modified radical mastectomy. A secondary objective was to assess the incidence of surgical site infection (SSI).Methods Patients undergoing modified radical mastectomy were randomly assigned to coated VICRYL* Plus antibacterial (Polyglactin 910) suture or Chinese silk suture. Cosmetic outcomes were evaluated postoperatively at days 12 (±2) and 30 (±5), and the evidence of SSI was assessed at days 3, 5, 7, 12 (±2), 30 (±5), and 90 (±7). Cosmetic outcomes were independently assessed via visual analogue scale (VAS) score evaluations of blinded incision photographs (primary endpoint) and surgeon-assessed modified Hollander Scale (mHCS) scores (secondary endpoint). SSI assessments used both CDC criteria and ASEPSIS scores.Results Six Chinese hospitals randomized 101 women undergoing modified radical mastectomy to closure with coated VICRYL* Plus suture (n=51) or Chinese silk suture (n=50). Mean VAS cosmetic outcome scores for antibacterial suture (67.2) were better than for Chinese silk (45.4) at day 30 (P 〈0.0001)). Mean mHCS cosmetic outcome total scores, were also higher for antibacterial suture (5.7) than for Chinese silk (5.0) at day 30 (P=0.002).Conclusions Patients using coated VICRYL* Plus suture had significantly better cosmetic outcomes than those with Chinese silk sutures. Patients using coated VICRYL* Plus suture had a lower SSI incidence compared to the Chinese silk sutures, although the difference did not reach statistical significance. (ClinicalTrials.gov NCT 00768222) 展开更多
关键词 ANTIBACTERIAL absorbable suture silk suture cosmesis surgical site infection
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乳腺癌保留乳房术后不同放疗模式近期临床观察 被引量:7
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作者 郭莹 乔学英 +3 位作者 宋玉芝 李静 周志国 杨立鑫 《中华肿瘤防治杂志》 CAS 北大核心 2013年第17期1340-1343,共4页
目的:观察T1-2N0-1M0期乳腺癌保留乳房术后3种不同的放疗方式在近期疗效以及放疗毒副作用之间的差异。方法:全乳三维适形放疗+瘤床电子线76例(适形组),全乳调强放疗+瘤床电子线22例(调强组),同步整合推量调强放疗41例(同步整合推量组),... 目的:观察T1-2N0-1M0期乳腺癌保留乳房术后3种不同的放疗方式在近期疗效以及放疗毒副作用之间的差异。方法:全乳三维适形放疗+瘤床电子线76例(适形组),全乳调强放疗+瘤床电子线22例(调强组),同步整合推量调强放疗41例(同步整合推量组),观察3组的生存率、急性皮肤反应和美容效果。结果:全组中位随访时间31.3个月,至末次随访时间所有患者均生存。1、2、3级急性皮肤反应适形组分别为60例(78.9%)、14例(18.4%)和2例(2.7%),调强组分别为19例(86.4%)、3例(13.6%)和0;同步整合推量组分别为37例(90.2%)、4例(9.8%)和0,χ2=2.737,P=0.254。适形组、调强组和同步整合推量组美容效果评价良好者分别为49例(64.5%)、19例(86.4%)和32例(78.0%),χ2=5.087,P=0.079。适形组、调强组和同步整合推量组的放疗天数分别为(50.7±5.9)、(47.8±5.5)和(39.6±4.2)d,F=56.889,P<0.001。结论:乳腺癌保留乳房术后同步整合推量调强放疗拥有与三维适形放疗+电子线和调强放疗+电子线相似的生存率、急性皮肤反应及美容效果,且治疗时间较短。 展开更多
关键词 乳腺肿瘤 外科学 放射疗法 毒副作用 美容效果
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Gold Standard for Skin Cancer Treatment: Surgery (Mohs) or Microscopic Molecular-Cellular Therapy (Curaderm)?
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作者 Bill Elliot Cham 《Journal of Cancer Therapy》 2024年第2期33-47,共15页
Non-melanoma skin cancers or keratinocyte cancers such as basal cell carcinoma and squamous cell carcinoma make up approximately 80% and 20% respectively, of skin cancers with the 6 million people that are treated ann... Non-melanoma skin cancers or keratinocyte cancers such as basal cell carcinoma and squamous cell carcinoma make up approximately 80% and 20% respectively, of skin cancers with the 6 million people that are treated annually in the United States. 1 in 5 Americans and 2 in 3 Australians develop skin cancer by the age of 70 years and in Australia it is the most expensive, amassing $1.5 billion, to treat cancers. Non-melanoma skin cancers are often self-detected and are usually removed by various means in doctors’ surgeries. Mohs micrographic surgery is acclaimed to be the gold standard for the treatment of skin cancer. However, a novel microscopic molecular-cellular non-invasive topical therapy described in this article, challenges the status of Mohs procedure for being the acclaimed gold standard. 展开更多
关键词 Skin Cancer Basal Cell Carcinoma Squamous Cell Carcinoma Mohs Surgery Microscopic Molecular-Cellular Curaderm Actinic Keratosis cosmesis
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三维腔镜全乳晕入路甲状腺切除术后患者生活质量及美容满意度的分析 被引量:6
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作者 王崇高 宋勇罡 +1 位作者 潘峰 朱乃海 《腹腔镜外科杂志》 2016年第4期267-270,共4页
目的:探讨三维腔镜全乳晕入路甲状腺切除术后患者生活质量及对美容满意度的分析。方法:为53例女性甲状腺手术患者分别行三维腔镜下全乳晕入路(观察组,n=28)与常规开放入路(对照组,n=25)甲状腺切除术,观察两组手术时间、术后并发症、生... 目的:探讨三维腔镜全乳晕入路甲状腺切除术后患者生活质量及对美容满意度的分析。方法:为53例女性甲状腺手术患者分别行三维腔镜下全乳晕入路(观察组,n=28)与常规开放入路(对照组,n=25)甲状腺切除术,观察两组手术时间、术后并发症、生活质量及美容满意度。结果:观察组患者均完成预定术式,手术时间长于对照组(P<0.05),两组患者术后并发症发生率差异无统计学意义(P>0.05),观察组术后生活质量及美容满意度明显优于对照组(P<0.05)。结论:三维腔镜全乳晕入路甲状腺手术美容效果明显,术后生活质量提高,掌握手术适应证、具备良好的腔镜手术技巧是保证手术成功的关键。 展开更多
关键词 甲状腺切除术 内窥镜检查 美容 生活质量
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辣椒素的皮肤美容作用及其应用的研究 被引量:5
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作者 赵赫龙 郑大威 《生物技术通报》 CAS CSCD 北大核心 2009年第S1期405-409,共5页
依据辣椒素的药理作用,提出将其应用于皮肤美容的领域。通过理论分析、动物试验以及人体皮肤实验,提出并验证了辣椒素对皮肤的美容效果的产生机理。结果,确定了含辣椒素的乳膏中所添加辣椒素的最佳浓度。给出了应用含辣椒素乳膏时不同... 依据辣椒素的药理作用,提出将其应用于皮肤美容的领域。通过理论分析、动物试验以及人体皮肤实验,提出并验证了辣椒素对皮肤的美容效果的产生机理。结果,确定了含辣椒素的乳膏中所添加辣椒素的最佳浓度。给出了应用含辣椒素乳膏时不同使用部位的最佳辣椒素含量的差别。对辣椒素在皮肤美容领域中的应用前景进行了分析。 展开更多
关键词 辣椒素 美容 皮肤微循环 最佳浓度 动物试验 应用
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红唇形态不佳的美容手术 被引量:5
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作者 谢洋春 范金才 《中国实用美容整形外科杂志》 2005年第6期357-359,共3页
目的为了改善形态不佳的红唇。方法根据红唇组织分布的特点,采用红唇部组织瓣转移及聚四氟乙烯填充的方法,来改善唇部组织的形态。对于单纯上唇红唇形态欠佳者,将上唇红唇两侧异常凸出组织,转移到不丰满的红唇中部;上唇红唇不显者,将口... 目的为了改善形态不佳的红唇。方法根据红唇组织分布的特点,采用红唇部组织瓣转移及聚四氟乙烯填充的方法,来改善唇部组织的形态。对于单纯上唇红唇形态欠佳者,将上唇红唇两侧异常凸出组织,转移到不丰满的红唇中部;上唇红唇不显者,将口角以口轮匝肌为蒂的下红唇组织瓣,转移到上唇;对于上下唇组织厚者,行厚唇修薄术;重唇者,去除重唇;上下唇均薄者,采用自体真皮脂肪瓣或人工生物材料(聚四氟乙烯)填充。结果本组患者30例,术后红唇形态满意,无切口愈合不良及皮瓣坏死,随访3个月至3年,效果满意。结论根据红唇形态不佳的特点,尽可能在红唇内部进行组织转移,如果上下红唇均不丰满,可结合自体组织或生物材料进行填充,来改善红唇的形态。 展开更多
关键词 红唇 转移 隆起 美容整形
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经脐单孔腹腔镜手术治疗妇科良性疾病的临床效果分析 被引量:3
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作者 苏彬 李艳 +3 位作者 唐文 李均 胡辉权 唐英 《妇产与遗传(电子版)》 2021年第2期21-25,共5页
目的比较经脐单孔腹腔镜与传统腹腔镜治疗妇科良性疾病的临床效果。方法回顾性分析比较2019年8月至2020年8月于川北医学院附属南充市中心医院初始治疗为手术的妇科良性疾病患者的临床效果,其中卵巢良性肿瘤132例,子宫肌瘤90例,子宫腺肌... 目的比较经脐单孔腹腔镜与传统腹腔镜治疗妇科良性疾病的临床效果。方法回顾性分析比较2019年8月至2020年8月于川北医学院附属南充市中心医院初始治疗为手术的妇科良性疾病患者的临床效果,其中卵巢良性肿瘤132例,子宫肌瘤90例,子宫腺肌症48例,卵巢子宫内膜异位囊肿45例,根据手术方式分为经脐单孔腹腔镜(观察组105例)和传统腹腔镜(对照组210例)两组,同时根据手术术式的不同将观察组、对照组再细分为子宫切除组(111例)、子宫肌瘤切除术组(27例)、卵巢良性肿瘤切除术组(177例)。结果两组均无中转开腹,术后均无并发症发生。观察组美容满意度评分、卵巢良性肿瘤组手术时间高于对照组(P<0.05);子宫肌瘤切除术和卵巢良性肿瘤的标本取出时间观察组低于对照组,差异有统计学意义(P<0.05);观察组的术后排气时间、术后住院时间、术后疼痛评分均低于对照组(P<0.05);两组比较,术中出血量、子宫肌瘤切除术和子宫切除术组手术时间无统计学差异(P>0.05)。结论经脐单孔腹腔镜手术具有美容满意度高、疼痛程度低、标本取出时间短等优点,有一定临床推广价值。 展开更多
关键词 腹腔镜检查 妇科良性疾病 标本取出时间 疼痛 美容
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Evaluation of an <i>in Situ</i>Polymerizing Hydrogel Applied in Tumor Excision Cavities during Breast Conservation Surgery
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作者 M. Korell F. Brassel J. Pagels 《Surgical Science》 2013年第10期464-468,共5页
Study Objective: To evaluate the imaging characteristics and healing following application of an absorbable biocompatible hydrogel into the excision cavity following breast conservation surgery. Design: Non-randomized... Study Objective: To evaluate the imaging characteristics and healing following application of an absorbable biocompatible hydrogel into the excision cavity following breast conservation surgery. Design: Non-randomized study evaluating hydrogel application feasibility, post-operative hydrogel imaging characteristics, cavity healing following hydrogel absorption and the resulting breast cosmesis. Setting: Teaching hospital University of Essen, Germany. Patients: Seven (7) patients underwent unilateral or bilateral breast conservation surgery to remove cancerous or benign tumors. Interventions: All patients received hydrogel application following primary tumor excision. Imaging performed in the first postoperative week included ultrasound, MRI and CT. Breast cosmesis scores were obtained at one and three months following surgery. Measurements and Main Results: While preliminary, a relationship between percent cavity filling and drainage was observed, with 30% or more cavity filling resulting in decreased drainage. Additionally, the hydrogel was readily visible under ultrasound, MRI and CT imaging modalities. Finally, patients were satisfied and surgeons felt that patient cosmesis was improved relative to their prior experience. Conclusion: Initial data suggest that hydrogel filling may reduce excision cavity drainage, which may reduce seroma or hematoma formation. Additionally, these gels may improve cavity visibility and stability, furthering the use of partial breast irradiation. Finally, while more studies are required, these materials may have a role in improving long term patient cosmesis. 展开更多
关键词 Lumpectomies BREAST Radiation SEROMA Prevention BREAST cosmesis
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Topical Curaderm<sup>BEC5</sup>Therapy for Periocular Nonmela-noma Skin Cancers: A Review of Clinical Outcomes
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作者 Bill E. Cham 《International Journal of Clinical Medicine》 2013年第5期233-238,共6页
Approximately 5 to 10 percent of all skin cancers occur in the periocular region. Basal cell carcinoma is the most frequent malignant periocular tumor, followed by squamous cell carcinoma, sebaceous gland carcinoma, a... Approximately 5 to 10 percent of all skin cancers occur in the periocular region. Basal cell carcinoma is the most frequent malignant periocular tumor, followed by squamous cell carcinoma, sebaceous gland carcinoma, and malignant melanoma. Nonmelanoma skin tumors at the periocular area often cause disfigurement with destruction of soft conjunctival tissue. Many therapeutic methods have been recommended to combat the morbidity and mortality associated with these lesions. Excisions with frozen-section control or Mohs micrographic surgery are regarded as the gold-standard treatments for periocular basal cell and squamous cell carcinomas. However, these treatment modalities have various limitations and reconstruction surgery is often associated with these treatment options. The chemotherapeutic agents solasodine rhamnosides in a cream formulation CuradermBEC5 are specific, effective and safe treatments for nonmelanoma skin cancers with excellent cosmesis. The antineoplastic mode of action is by apoptosis. In this review it is shown that CuradermBEC5 also treats periocular basal cell carcinoma and squamous cell carcinoma with impressive cosmetic outcomes and no reconstructive surgery is required. 展开更多
关键词 Periocular Skin Cancers CuradermBEC5 Apoptosis SOLAMARGINE Basal CELL CARCINOMA Squamous CELL CARCINOMA cosmesis SOLANUM
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Reduced port surgery for appendectomy:Early experience and surgical technique
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作者 Shinichiro Mori Kenji Baba +9 位作者 Shigehiro Yanagita Yoshiaki Kita Kosei Maemura Yuko Mataki Yasuto Uchikado Hiroshi Okumura Tetsuhiro Nakajyo Shoji Natsugoe Sonshin Takao Kuniaki Aridome 《World Journal of Surgical Procedures》 2013年第2期8-12,共5页
AIM: To evaluate our experience and surgical technique of laparoscopic appendectomy via reduced port surgery(LARPS). METHODS: Sixteen patients(8 men and 8 women; median age: 31.0 years) who underwent LARPS between Nov... AIM: To evaluate our experience and surgical technique of laparoscopic appendectomy via reduced port surgery(LARPS). METHODS: Sixteen patients(8 men and 8 women; median age: 31.0 years) who underwent LARPS between November 2009 and May 2012 were included in the present study. We performed LARPS, in which access devices were inserted through an umbilical skin incision with 1 additional skin incision in the left lower abdomen. After setting access devices, pneumoperitoneum was maintained at 10 mmH g using CO2 and a 3 mm trocar was positioned(or direct puncture was performed by the Endo Relief system) under laparoscopic guidance. The mesoappendix was dissected using an ultrasonically activated device. After mesoappendix dissection, ligation was performed near the appendix base and the appendix was dissected using an ultrasonically activated device. The appendix was then removed. At the end of surgery, we administered local anesthesia with ropivacaine 1%(10 mL) for the skin incisions. The outcomes were evaluated in terms of operation time, intraoperative blood loss, length of postoperative hospital stay and surgical complications. RESULTS: Our surgical procedure allowed operators to use instruments as in conventional laparoscopic appendectomy. The basic principle of triangulation of instrumentation was maintained to some degree. LARPS was performed in 9 patients with catarrhal appendicitis, 5 with phlegmonous appendicitis, and 2 with gangrenous appendicitis. The median surgery time was 60 min and the median intraoperative blood loss was 1.2 mL. The median length of postoperative hospitalization was 4 d. There were no conversions to open surgery, no operation-related complications or mortality. CONCLUSION: Our experience and surgical technique suggest that LARPS is a safe and feasible procedure for patients with appendicitis. 展开更多
关键词 REDUCED PORT SURGERY APPENDECTOMY Laparoscopy cosmesis Single INCISION
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Histological Findings of a Local Adipofascial Flap That Was Implanted during Breast Conserving Surgery
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作者 Yuko Kijima Heiji Yoshinaka +5 位作者 Munetsugu Hirata Akihiro Nakajo Hideo Arima Sumiya Ishigami Shinichi Ueno Shoji Natsugoe 《Modern Plastic Surgery》 2013年第1期43-46,共4页
We report a patient with breast cancer whose breast was immediately reconstructed using a local adipofascial flap and was then subsequently resected 3 years after the original surgical procedure due to local recurrenc... We report a patient with breast cancer whose breast was immediately reconstructed using a local adipofascial flap and was then subsequently resected 3 years after the original surgical procedure due to local recurrence. In order to achieve local control of the solitary recurrent lesion, we resected the remnant breast, which gave us a useful opportunity to examine the previously implanted flap histologically. A 33-year-old Japanese female was diagnosed with T2N0M0 breast cancer in the outer area of her left breast and underwent partial mastectomy with immediate reconstruction using a local adipofascial flap. The breast lesion was considered to be invasive ductal carcinoma, scirrhous carcinoma, lymphatic invasion+, venous invasion-, estrogen receptor+, progesterone receptor+, and HER2/neu-. Involvement was noted in three of the twenty-five resected axillary lymph nodes. She received adjuvant hormone therapy, but developed a solitary local recurrence of the skin forty-five months after the initial procedure, for which she received total mastectomy, systemic chemotherapy, and hormone therapy. During the histological examination of the local adipofascial flap that had been implanted into the partial breast defect, normal fatty tissue and the implanted fascia were seen at the implantation site. This is a rare report in which a local flap that was implanted during oncoplastic breast surgery was histologically examined. 展开更多
关键词 Breast Cancer ONCOPLASTIC Surgery LOCAL Adipofascial FLAP cosmesis Thoracodorsal Adipofascial FLAP
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自体脂肪注射修复体表凹陷畸形 被引量:2
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作者 朱兴华 张云 胡克苏 《江苏医药》 CAS CSCD 北大核心 2007年第9期891-892,共2页
目的采用自体颗粒脂肪抽吸与注射,探讨修复体表凹陷畸形的一种简便、安全有效方法。方法选择17例体表局部凹陷畸形患者,供区肿胀麻醉后以专用抽吸针低负压抽吸脂肪颗粒,清洗后将其注入凹陷部位。结果随访6个月~3年,凹陷畸形修复满意,... 目的采用自体颗粒脂肪抽吸与注射,探讨修复体表凹陷畸形的一种简便、安全有效方法。方法选择17例体表局部凹陷畸形患者,供区肿胀麻醉后以专用抽吸针低负压抽吸脂肪颗粒,清洗后将其注入凹陷部位。结果随访6个月~3年,凹陷畸形修复满意,无感染或其他并发症病例。结论自体颗粒脂肪注射可安全有效地用于体表凹陷畸形的修复。 展开更多
关键词 脂肪 整形 美容
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乳腺癌改良根治术后假体置入即刻乳房再造的研究 被引量:2
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作者 傅建民 刘立刚 《广西医学》 CAS 2007年第6期801-802,共2页
目的 研究实施乳腺癌改良根治加术后假体置入即刻乳房再造手术治疗早期乳腺癌的可行性和推广这种术式的可能性。方法 对临床Ⅰ、Ⅱ期乳腺癌或者低度恶性肿瘤的病人,实施了乳腺癌改良根治术后即刻乳房再造手术。术前检查明确有无手术指... 目的 研究实施乳腺癌改良根治加术后假体置入即刻乳房再造手术治疗早期乳腺癌的可行性和推广这种术式的可能性。方法 对临床Ⅰ、Ⅱ期乳腺癌或者低度恶性肿瘤的病人,实施了乳腺癌改良根治术后即刻乳房再造手术。术前检查明确有无手术指征,常规实施保留胸大肌和胸小肌的乳腺癌改良根术,按自愿选择的原则采用即刻乳房再造手术。根据术后病理情况及其他预后指标决定术后辅助治疗方案,分别于术后3、6、12个月评价即刻乳房再造手术的美容效果。结果 共实施乳腺癌改良根治术后假体置入即刻乳房再造手术15例,占同期乳腺恶性肿瘤手术病人的2.2%。肿瘤直径1.5~11.0cm,术后病理浸润性导管癌11例,黏液腺癌1例,叶状囊肉瘤3例。全部病例随访未发现复发和转移,1例术后出现轻度假体移位,1例放疗后出现假体轻度萎缩,美容效果不理想。结论 乳腺癌改良根治加术后假体置入即刻乳房再造手术美容效果良好,可显著提高乳腺癌患者的生活质量。 展开更多
关键词 乳腺肿瘤 根治术 乳房再造术 乳房假体 生活质量
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Subjective scar assessment scales in orthopaedic surgery and determinants of patient satisfaction: A systematic review of the literature
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作者 Diego A Abelleyra Lastoria Clerin K Benny Caroline B Hing 《Chinese Journal of Traumatology》 CAS CSCD 2023年第5期276-283,共8页
Purpose:Scar assessment tools can be utilized during the post-operative period to monitor scar progress.The primary aim of this systematic review was to evaluate current subjective scar assessment scales utilized in o... Purpose:Scar assessment tools can be utilized during the post-operative period to monitor scar progress.The primary aim of this systematic review was to evaluate current subjective scar assessment scales utilized in orthopaedic surgery.The secondary aim was to identify determinants of patients'satisfaction with their scars and evaluate current measurement scales.Methods:The preferred reporting items for systematic reviews and meta-analyses checklist was followed.Electronic databases,curently registered studies,conference proceedings and the reference lists of included studies were searched.There were no constraints based on language or publication status.A narrative synthesis provided a description and evaluation of scales utilized in orthopaedic surgery.Determinants of patient satisfaction were identified along with the scales used to measure satisfaction.Results:A total of 6059 records were screened in the initial search.Twenty-six articles satisfied the inclusion criteria,assessing 7130 patients.In the literature,six validated subjective scar scales were identified,including the Vancouver scar scale,patient and observer scar assessment scale,Manchester scar scale,Stony Brook scar evaluation scale,visual analogue scale,and Hollander wound evaluation scale.Studies utilizing these scales to evaluate scars following orthopaedic procedures did so successfully.These were total hip arthroplasty,total knee arthroplasty,and limb reconstruction.The scales demonstrated satisfactory validity.Functional outcomes such as restoration of movement ranked among patients'highest concerns.Scar cosmesis was found to be amongst patients'lowest priorities.Conclusions:Subjective scar assessment scales identified in the literature were not designed specifically for orthopaedic surgery.However,these were able to appropriately assess scars in the studies identified in this review.Current evidence suggests the effect of scar cosmesis on patient satisfaction with orthopaedic procedures is limited. 展开更多
关键词 SCAR cosmesis ORTHOPAEDICS Patient satisfaction
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乳腺癌保留乳房治疗的适应证与美容效果 被引量:1
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作者 杨红健 邹德宏 +4 位作者 谢尚闹 孟旭莉 俞洋 孙才兴 陈道宝 《肿瘤防治杂志》 2005年第11期867-868,共2页
对62例早期乳腺癌患者施行了保留乳房局部治疗和辅助全身治疗,并对其临床资料、手术技术和治疗后美容效果进行了分析。62例患者无局部复发,术后1年美容效果评价良好57例,一般5例,美容效果满意率100%。分析结果表明,掌握早期乳腺癌患者... 对62例早期乳腺癌患者施行了保留乳房局部治疗和辅助全身治疗,并对其临床资料、手术技术和治疗后美容效果进行了分析。62例患者无局部复发,术后1年美容效果评价良好57例,一般5例,美容效果满意率100%。分析结果表明,掌握早期乳腺癌患者行保留乳房治疗的适应证,注意手术技巧,可取得满意的美容效果。 展开更多
关键词 乳腺肿瘤/ 外科学 乳房切除术 美容
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Cosmetic outcome of femtosecond laserassisted pterygium surgery 被引量:1
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作者 Darren Shu Jeng Ting Yu-Chi Liu +4 位作者 Yi Fang Lee Angel Jung Se Ji Tien-En Tan Hla M.Htoon Jodhbir S.Mehta 《Eye and Vision》 SCIE CSCD 2021年第1期59-66,共8页
Background:To examine the cosmetic outcome of femtosecond laser-assisted pterygium surgery(FLAPS)with conjunctival autograft(CAG)and its potential predictive factors.Methods:This was a prospective interventional case ... Background:To examine the cosmetic outcome of femtosecond laser-assisted pterygium surgery(FLAPS)with conjunctival autograft(CAG)and its potential predictive factors.Methods:This was a prospective interventional case series(NCT02866968).We included 29 patients(29 eyes)with primary pterygium who underwent FLAPS.Cosmetic outcome was graded by two graders(an ophthalmology resident and an experienced ophthalmologist)using Hirst classification system(1-4=excellent-poor).Weighted Cohen’s kappa analysis was performed to examine the intra-and inter-rater reliability.The relationship between cosmetic outcome and various factors were determined by Spearman’s correlation coefficients(r).Results:The preoperative severity of pterygium(Tan grading system)was mild/atrophic(7%),moderate/intermediate(62%),and severe/fleshy(31%).An ultrathin CAG(mean thickness of 74.5±9.8μm)was fashioned intraoperatively.An excellent cosmetic outcome of FLAPS(median±IQR)was observed at 3 months(1.0±1.0)and remained similar at 6months(1.0±0.0)and 12months(1.0±0.0)postoperatively.At final follow-up,27(93%)patients achieved good-to-excellent cosmetic outcome,with 1(3%)patient having a poor outcome due to incomplete pterygium removal.Weighted kappa analysis of Hirst grading system showed excellent intra-rater(κ=0.86-0.95)and inter-rater reliability(κ=0.84-0.88).There was a weak and borderline significant correlation between good cosmetic outcome and reduced postoperative CAG thickness(r=0.38,P=0.06)but not with age,gender,preoperative pterygium severity,or intraoperative CAG thickness.Conclusions:FLAPS can result in an excellent cosmetic outcome,which may be attributed to the beneficial effect of an ultrathin CAG. 展开更多
关键词 cosmesis Cosmetic outcome Femtosecond laser PTERYGIUM Pterygium surgery
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Comparison of cosmetic outcomes between remote-access and conventional thyroidectomy:A review of the current literature
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作者 Anna Kasouli Eleftherios Spartalis +3 位作者 Alexios Giannakodimos Gerasimos Tsourouflis Dimitrios Dimitroulis Nikolaos I.Nikiteas 《World Journal of Otorhinolaryngology-Head and Neck Surgery》 CSCD 2023年第1期1-8,共8页
Objective:The pursuit of an esthetically pleasing scar following open thyroid surgery has led to the development of endoscopic thyroidectomy through remote incisions placed in several locations outside the neck.The ob... Objective:The pursuit of an esthetically pleasing scar following open thyroid surgery has led to the development of endoscopic thyroidectomy through remote incisions placed in several locations outside the neck.The objective of this study is to review the recent literature and compare the incision site appearance and patient satisfaction with the cosmetic outcome after extracervical and conventional thyroidectomy.Methods:The English literature published since 2010 was searched through the PubMed/Medline database for studies comparing the cosmetic outcomes between remote-access endoscopic and conventional thyroidectomy using a form of scar assessment scale.Results:A total of 9 relevant papers fulfilled the eligibility criteria including 1486 patients.Among them,595 patients underwent endoscopic thyroidectomy through several remote-access approaches and 891 patients were assigned to the conventional group.Only one randomized-controlled trial was identified,whereas among the rest,four were prospective and four were retrospective nonrandomized cohorts.Regarding the extracervical modifications performed in the endoscopic groups,the axillary approach was performed in three studies and the breast approach in four studies,while the retroauricular facelift technique and the transoral vestibular method were applied in one study,respectively.Conclusions:Evaluation of the wound appearance and patient satisfaction with the cosmetic outcome at various time points during the follow-up highlighted the superiority of the extracervical approaches over the conventional cervicotomy.Considering these findings,remote-access techniques could possibly be the ideal surgical method for patients with high esthetic requirements,providing an excellent appearance of the thoroughly exposed neck. 展开更多
关键词 ESTHETIC cosmesis COSMETIC cosmetic results INCISION SCAR THYROIDECTOMY
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Cosmetic outcome of femtosecond laserassisted pterygium surgery
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作者 Darren Shu Jeng Ting Yu-Chi Liu +4 位作者 Yi Fang Lee Angel Jung Se Ji Tien-En Tan Hla M.Htoon Jodhbir S.Mehta 《Eye and Vision》 SCIE CSCD 2023年第1期33-40,共8页
Background:To examine the cosmetic outcome of femtosecond laser-assisted pterygium surgery(FLAPS)with conjunctival autograft(CAG)and its potential predictive factors.Methods:This Was a prospective interventional case ... Background:To examine the cosmetic outcome of femtosecond laser-assisted pterygium surgery(FLAPS)with conjunctival autograft(CAG)and its potential predictive factors.Methods:This Was a prospective interventional case series(NCT02866968).We included 29 patients(29 eyes)with primary pterygium who underwent FLAPS.Cosmetic outcome was graded by two graders(an ophthalmology resident and an experienced ophthalmologist)using Hirst classification system(1-4:excellent-poor).Weighted Cohen's kappa analysis was performed to examine the intra-and inter-rater reliability.The relationship between cosmetic outcome and various factors were determined by Spearman's correlation coefficients(r).Results:The preoperative severity of pterygium(Tan grading system)was mild/atrophic(7%),moderate/intermediate(62%),and severe/fleshy(31%).An ultrathin CAG(mean thickness of 74.5±9.8μm)was fashioned intraoperatively.An excellent cosmetic outcome of FLAPS(median±IQR)was observed at 3 months(1.0±1.0)and remained similar at 6 months(1.0±0.0)and 12 months(1.0±0.0)postoperatively.At final fllow-up,27(93%)patients achieved good-to-excellent cosmetic outcome,with 1(3%)patient having a poor outcome due to incomplete pterygium removal.Weighted kappa analysis of Hirst grading system showed excellent intra-rater(k:0.86-0.95)and inter-rater reliability(k:0.84-0.88).There was a weak and borderline significant correlation between good cosmetic outcome and reduced postoperative CAG thickness(r=0.38,P=0.06)but not with age,gender,preoperative pterygium severity,or intraoperative CAG thickness.Conclusions:FLAPS can result in an excellent cosmetic outcome,which may be attributed to the beneficial effect of an ultrathinCAG.Trial registration:ClinicalTrials.gov,NCT02866968.Registered in July 2016. 展开更多
关键词 cosmesis Cosmetic outcome Femtosecond laser PTERYGIUM Pterygium surgery
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强脉冲光对长波紫外线Ⅰ诱导成纤维细胞光损伤的保护作用 被引量:1
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作者 刘红梅 刘玮 +3 位作者 赵小忠 田燕 袁小英 王瑞艳 《中华医学美学美容杂志》 2011年第2期117-120,共4页
目的 研究强脉冲光(intense pulse light,IPL)对长波紫外线(ultraviolet A,UVA Ⅰ)诱导的正常离体人皮肤成纤维细胞(fibroblast,FB)损伤的保护作用,探讨以IPL为手段的光子嫩肤技术的理论基础.方法 分离并培养人FB,用不同剂量UVA ... 目的 研究强脉冲光(intense pulse light,IPL)对长波紫外线(ultraviolet A,UVA Ⅰ)诱导的正常离体人皮肤成纤维细胞(fibroblast,FB)损伤的保护作用,探讨以IPL为手段的光子嫩肤技术的理论基础.方法 分离并培养人FB,用不同剂量UVA Ⅰ照射FB以诱导细胞光损伤,CCK-8检测其增殖能力的情况,根据预实验结果确定IPL剂量进行照射,流式细胞仪技术枪测细胞周期,Western印迹法检测CylinD1和CDK2蛋白的表达水平.结果 不同剂量的UVA Ⅰ可造成FB的损伤,随着UVA Ⅰ剂量的增加,细胞增殖能力下降,11 J/cm2的剂量可明显导致细胞大量死亡,而7 J/cm2的UVAⅠ对细胞的增殖能力没有明显的影响;经UVA Ⅰ照射2 d后再进行IPL连续照射2 d,细胞增殖活性高于单独UVA Ⅰ处理组,差异具有统计学意义.流式细胞仪检测结果表明该组细胞增殖指数升高.细胞周期蛋白CyclinD1和CDK2的表达水平升高.结论 IPL可通过调节周期蛋白的表达而促进正常FB增殖,从而保护UVAⅠ诱导的FB光损伤,为应用IPL面部美容除皱即光子嫩肤术提供理论依据. 展开更多
关键词 强脉冲光 增殖 细胞周期 美容
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生物陶瓷中空义眼座的研制与临床应用
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作者 王利群 贾洪民 +2 位作者 孟庆荣 宋厚兰 张建洛 《河南医学研究》 CAS 1996年第3期213-214,共2页
22例(22眼)眼球摘除患者植入了我们研制的生物陶瓷中空义眼座。随访1~3年,发现此种义眼座无感染及排异反应。结果表明,生物陶瓷中空义眼座重量轻、生物相容性好,美容效果满意。
关键词 生物陶瓷 义眼座 研制 临床应用 眼外科手术
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