摘要
目的 探讨静脉注射纤维蛋白原制剂在消耗性凝血病治疗中的临床价值.方法 将41例弥漫性血管内凝血(DIC)患者分成两组,使用纤维蛋白原组21例和未使用纤维蛋白原组20例.观察两组患者的凝血功能、凝血机能出现好转所需时间、治愈率及不良反应等.结果 使用纤维蛋白原组凝血功能好转明显,且凝血机能好转所需时间明显少于未使用纤维蛋白原组,但两组患者治愈率差异无统计学意义(P>0.05).结论 静脉注射纤维蛋白原在DIC、出现低纤维蛋白原血症者中能改善凝血功能、加快凝血机能好转,为进一步治疗创造条件,在临床应用中安全、可靠、有效.
Objective To investigate the clinical value of intravenous fibrinolytic agents in the treatment of patients with consumptive coagulopathy. Methods Forty-one patients with diffuse intravascular coagulation(DIC)were divided into two groups:21 in fibrinogen group and 20 in fibrinolytic group. The coagulation function,the time required for improvement of coagulation function,the cure rate and adverse reactions were observed in two groups of patients. Results The fibrinogen group showed a significant improvement in the coagulation function,and the time required for improvement of the coagulation function was significantly less than that of the fibrinogen group. However,there was no significant difference in the cure rate between the two groups(P>0.05). Conclusion Intravenous injection of fibrinogen in DIC,hypofibrinogenemia can improve coagulation, accelerate the improvement of blood coagulation,and create conditions for further treatment,which is safe,reliable and effective in clinical application.
出处
《浙江临床医学》
2018年第12期2006-2007,共2页
Zhejiang Clinical Medical Journal
基金
浙江省医学会临床科研基金(2016ZYC-A96).
关键词
纤维蛋白原
弥漫性血管内凝血
疗效
Fibrinogen
Diffuse intravascular coagulation
Curative effect
