摘要
目的：评价盐酸利多卡因术中静脉输注对腹腔镜胃癌根治术后镇痛效果的影响。方法选择择期全麻下腹腔镜胃癌根治术的病人60例，按随机数字表法随机分为研究组和对照组，按照标准化方案麻醉诱导和维持，研究组于麻醉诱导即刻静脉注射盐酸利多卡因1.5mg·kg-1，术中以2mg·kg-1·h-1速率输注至术毕，对照组术中给予同样速率输注乳酸林格液。术后分别于呼之能应即刻（T0），术毕2h（T1），8h（T2），24h（T3），48h（T4）进行VAS镇痛评分和Ramsay镇静评分，并记录术后48h以内病人对镇痛药物的进一步需求情况。结果研究组VAS评分在T2（P=0.000），T3（P=0.001），T4（P=0.007）明显低于对照组，研究组Ramsay镇静评分在T0，T1，T2，T3，T4各时间点均明显高于对照组（P<0.05），术后48h内研究组仅有1例患者要求进一步镇痛，对照组有8例，研究组明显低于对照组（P<0.05）。结论盐酸利多卡因术中静脉输注对腹腔镜胃癌根治手术患者的术后镇痛效果的优化作用明显，值得临床推广应用。
objective To evaluate the effect of postoperative analgesic of intraoperative lidocaine hydrochloride by the intravenous infusion after the application of laparoscopic radical prostatectomy for gastric carcinoma.Methods 60 patients under GA were randomly divided into the study group and the control group.According to the standardized narcotic induction and maintenance,,the study group was given intravenous lidocaine hydrochloride injection (1.5mg·kg-1)immediately after anesthetic induction,then with the rate of infusion (2 mg·kg-1·h-1)till the end of the operation.The control group received Lactate Ringer's solution infusion.VAS scores and Ramsay sedation scores were recorded when sobered?up immediately (T0)and 2h (T1),8h(T2), 24h(T3),48h(T4)postoperatively.Patients’ further demand for analgesic drugs postopertion was recorded at the same time.Results The study group’s VAS scores were obviously higher than that of the control group at the moment of T2,T3,T4(P<0.05);its ramsay sedation scores were clearly lower than the control group’s at the moment of T0,T1,T2,T3,T4 (P<0.05),and its patients’ further demand for analgesia drugs significantly lower than the control group’s(P<0.05). Conclusion Intraoperative intravenous lidocaine performed effectively in postoperative analgesia for patients with laparoscopic radical prostatectomy for gastric carcinoma ,which is worth promoting.
出处
《哈尔滨医药》
2016年第S1期15-16,共2页
Harbin Medical Journal
关键词
利多卡因
术后镇痛
非麻醉作用
腹腔镜
Lidocaine
Postoperative analgesia
Non-anesthetic effects
Laparoscope
