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Detection of Angioectasias and Haemorrhages Incorporated into a Multi-Class Classification Tool for the GI Tract Anomalies by Using Binary CNNs

Detection of Angioectasias and Haemorrhages Incorporated into a Multi-Class Classification Tool for the GI Tract Anomalies by Using Binary CNNs
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摘要 The proposed deep learning algorithm will be integrated as a binary classifier under the umbrella of a multi-class classification tool to facilitate the automated detection of non-healthy deformities, anatomical landmarks, pathological findings, other anomalies and normal cases, by examining medical endoscopic images of GI tract. Each binary classifier is trained to detect one specific non-healthy condition. The algorithm analyzed in the present work expands the ability of detection of this tool by classifying GI tract image snapshots into two classes, depicting haemorrhage and non-haemorrhage state. The proposed algorithm is the result of the collaboration between interdisciplinary specialists on AI and Data Analysis, Computer Vision, Gastroenterologists of four University Gastroenterology Departments of Greek Medical Schools. The data used are 195 videos (177 from non-healthy cases and 18 from healthy cases) videos captured from the PillCam<sup>(R)</sup> Medronics device, originated from 195 patients, all diagnosed with different forms of angioectasia, haemorrhages and other diseases from different sites of the gastrointestinal (GI), mainly including difficult cases of diagnosis. Our AI algorithm is based on convolutional neural network (CNN) trained on annotated images at image level, using a semantic tag indicating whether the image contains angioectasia and haemorrhage traces or not. At least 22 CNN architectures were created and evaluated some of which pre-trained applying transfer learning on ImageNet data. All the CNN variations were introduced, trained to a prevalence dataset of 50%, and evaluated of unseen data. On test data, the best results were obtained from our CNN architectures which do not utilize backbone of transfer learning. Across a balanced dataset from no-healthy images and healthy images from 39 videos from different patients, identified correct diagnosis with sensitivity 90%, specificity 92%, precision 91.8%, FPR 8%, FNR 10%. Besides, we compared the performance of our best CNN algorithm v The proposed deep learning algorithm will be integrated as a binary classifier under the umbrella of a multi-class classification tool to facilitate the automated detection of non-healthy deformities, anatomical landmarks, pathological findings, other anomalies and normal cases, by examining medical endoscopic images of GI tract. Each binary classifier is trained to detect one specific non-healthy condition. The algorithm analyzed in the present work expands the ability of detection of this tool by classifying GI tract image snapshots into two classes, depicting haemorrhage and non-haemorrhage state. The proposed algorithm is the result of the collaboration between interdisciplinary specialists on AI and Data Analysis, Computer Vision, Gastroenterologists of four University Gastroenterology Departments of Greek Medical Schools. The data used are 195 videos (177 from non-healthy cases and 18 from healthy cases) videos captured from the PillCam<sup>(R)</sup> Medronics device, originated from 195 patients, all diagnosed with different forms of angioectasia, haemorrhages and other diseases from different sites of the gastrointestinal (GI), mainly including difficult cases of diagnosis. Our AI algorithm is based on convolutional neural network (CNN) trained on annotated images at image level, using a semantic tag indicating whether the image contains angioectasia and haemorrhage traces or not. At least 22 CNN architectures were created and evaluated some of which pre-trained applying transfer learning on ImageNet data. All the CNN variations were introduced, trained to a prevalence dataset of 50%, and evaluated of unseen data. On test data, the best results were obtained from our CNN architectures which do not utilize backbone of transfer learning. Across a balanced dataset from no-healthy images and healthy images from 39 videos from different patients, identified correct diagnosis with sensitivity 90%, specificity 92%, precision 91.8%, FPR 8%, FNR 10%. Besides, we compared the performance of our best CNN algorithm v
作者 Christos Barbagiannis Alexios Polydorou Michail Zervakis Andreas Polydorou Eleftheria Sergaki Christos Barbagiannis;Alexios Polydorou;Michail Zervakis;Andreas Polydorou;Eleftheria Sergaki(School of Electrical and Computer Engineering (ECE) School, Technical University of Crete, Chania, Greece;Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece)
出处 《Journal of Biomedical Science and Engineering》 2021年第12期402-414,共13页 生物医学工程(英文)
关键词 Capsule Endoscopy (CE) Small Bowel Bleeding (SBB) Angioectasia Haemorrhage Gatrointestinal (GI) Small Bowel Capsule Endoscopy (SBCE) Convolutional Neural Network (CNN) Computer Aided Diagnosis (CAD) Image Level Annotation Pixel Level Annotation Binary Classification Capsule Endoscopy (CE) Small Bowel Bleeding (SBB) Angioectasia Haemorrhage Gatrointestinal (GI) Small Bowel Capsule Endoscopy (SBCE) Convolutional Neural Network (CNN) Computer Aided Diagnosis (CAD) Image Level Annotation Pixel Level Annotation Binary Classification
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