摘要
This study investigated the effects of yerba mate consumption, a South American beverage, on cardiac remodeling in rats. For this purpose, 24 male Wistar rats were divided into Control Group (CG) which received filtered water and a standard diet, and Yerba Mate Group (YM), 6 g of Ilex paraguariensis in 100 ml water and the same diet, for 30 days. The YM group showed a reduction in final body weight and food consumption without altering weight gain. Regarding cardiac remodeling, the YM group exhibited a decrease in the right ventricle weight/final body weight ratio, suggesting cardiac atrophy, without affecting the atria and left ventricle. There was no change in cardiomyocyte area or nuclear fractal dimension in both groups. However, animals that consumed yerba mate showed increased collagen deposition and a smaller fractal dimension in the left ventricle. The consumption of yerba mate at room temperature for 30 days induced changes in cardiac remodeling, as evidenced by increased collagen deposition and alterations in fractal dimension in the left ventricle.
This study investigated the effects of yerba mate consumption, a South American beverage, on cardiac remodeling in rats. For this purpose, 24 male Wistar rats were divided into Control Group (CG) which received filtered water and a standard diet, and Yerba Mate Group (YM), 6 g of Ilex paraguariensis in 100 ml water and the same diet, for 30 days. The YM group showed a reduction in final body weight and food consumption without altering weight gain. Regarding cardiac remodeling, the YM group exhibited a decrease in the right ventricle weight/final body weight ratio, suggesting cardiac atrophy, without affecting the atria and left ventricle. There was no change in cardiomyocyte area or nuclear fractal dimension in both groups. However, animals that consumed yerba mate showed increased collagen deposition and a smaller fractal dimension in the left ventricle. The consumption of yerba mate at room temperature for 30 days induced changes in cardiac remodeling, as evidenced by increased collagen deposition and alterations in fractal dimension in the left ventricle.
作者
Carlos Eduardo Brochini de Paiva
Thaíssa Baptista Brochini de Paiva
Isabelle Tiburcio Pecin Ferreira
Sandra Cristina Genaro
Danilo Silva Martins Santos
Thaoan Bruno Mariano
Robson Chacon Castoldi
Rafael Stuani Floriano
Julia Amanda Rodrigues Fracasso
Lucas Pires Guarnier
Marina Politi Okoshi
Francis Lopes Pacagnelli
Carlos Eduardo Brochini de Paiva;Thaíssa Baptista Brochini de Paiva;Isabelle Tiburcio Pecin Ferreira;Sandra Cristina Genaro;Danilo Silva Martins Santos;Thaoan Bruno Mariano;Robson Chacon Castoldi;Rafael Stuani Floriano;Julia Amanda Rodrigues Fracasso;Lucas Pires Guarnier;Marina Politi Okoshi;Francis Lopes Pacagnelli(Postgraduate Program in Health Sciences, Unoeste, Presidente Prudente, Brazil;Faculty of Medicine, Unoeste, Presidente Prudente, Brazil;Department of Physiotherapy, Unoeste, Presidente Prudente, Brazil;Department of Nutrition, Unoeste, Presidente Prudente, Brazil;Postgraduate Program in Science and Movement, Unesp, Rio Claro, Brazil;Postgraduate Program in Health Promotion, University of Northern Paran (UNOPAR), Londrina, Brazil;School of Dentistry, So Paulo State University (UNESP), Araatuba, Brazil;Department of Genetics, Ribeiro Preto Medical School, University of So Paulo, USP, Ribeiro Preto, Brazil;Internal Medicine Department, Botucatu Medical School, So Paulo State University (UNESP), Botucatu, Brazil)