摘要
Phytochemical screening and assay of secondary metabolites, crude extracts with distilled water, aqueous methanol, aqueous acetone and aqueous ethanol of leaves and seeds of Senna occidentalis L. were studied in this work. The aim was to verify the distribution of secondary metabolites according to S. occidentalis organs. Four leaf samples from four different localities (South, East, West and Central Senegal) and a mixed sample of seeds were used. Functional molecules such as polyphenols, flavonoids and tannins were then assessed in the leaves and seeds using various standard methods. The results show that Senna occidentalis L. leaf and seed samples display an identical and homogeneous profile, regardless of locality. They contain secondary metabolites and the polyphenol content of extracts from southern, eastern, western and central leaves is: 0.620 - 0.539 - 0.811 - 0.573 g GAE/100 g DM;flavonoids: 0.064 - 0.074 - 0.130 - 0.101 g CE/100 g DM and tannins: 0.326 - 0.264 - 0.269 - 0.494 g TAE/100 g DM. The efficacy of S. occidentalis L. infusions in therapy is thus justified by the presence of these metabolites, whose biological properties are well known. It is then possible to explore isolation of active principles of Senna occidentalis L. leaves and even seeds for producing medicines.
Phytochemical screening and assay of secondary metabolites, crude extracts with distilled water, aqueous methanol, aqueous acetone and aqueous ethanol of leaves and seeds of Senna occidentalis L. were studied in this work. The aim was to verify the distribution of secondary metabolites according to S. occidentalis organs. Four leaf samples from four different localities (South, East, West and Central Senegal) and a mixed sample of seeds were used. Functional molecules such as polyphenols, flavonoids and tannins were then assessed in the leaves and seeds using various standard methods. The results show that Senna occidentalis L. leaf and seed samples display an identical and homogeneous profile, regardless of locality. They contain secondary metabolites and the polyphenol content of extracts from southern, eastern, western and central leaves is: 0.620 - 0.539 - 0.811 - 0.573 g GAE/100 g DM;flavonoids: 0.064 - 0.074 - 0.130 - 0.101 g CE/100 g DM and tannins: 0.326 - 0.264 - 0.269 - 0.494 g TAE/100 g DM. The efficacy of S. occidentalis L. infusions in therapy is thus justified by the presence of these metabolites, whose biological properties are well known. It is then possible to explore isolation of active principles of Senna occidentalis L. leaves and even seeds for producing medicines.
作者
Edmond Antoine Badock
Lahat Niang
Abdoulaye Dramé
Célestine Nkounkou-Loumpangou
Omar Touré
Omar Sokhna
Nicolas Cyrille Ayessou
Mady Cissé
Edmond Antoine Badock;Lahat Niang;Abdoulaye Dramé;Célestine Nkounkou-Loumpangou;Omar Touré;Omar Sokhna;Nicolas Cyrille Ayessou;Mady Cissé(Ecole Suprieure Polytechnique, Laboratoire Eau, Energie, Environnement et Procds Industriels (LE3PI), Universit Cheikh Anta Diop, Dakar, Sngal;Ecole Suprieure Polytechnique, Centre dEtudes sur la Scurit Alimentaire et les Molcules Fonctionnelles (CESAM-RESCIF), Universit Cheikh Anta Diop, Dakar, Sngal;Laboratoire de Valorisation des Produits de la Biomasse, Dpartement de Chimie, Universit Cheikh Anta Diop de Dakar, Dakar, Sngal;Unit de Chimie du Vgtal et de la Vie, Facult des Sciences et Techniques, Universit Marien NGOUABI, Brazzaville, Republic of the Congo;Laboratoire de Chimie Organique et Bio-Organique, Dpartement de Chimie, Facult des Sciences et Techniques/UCAD, Universit Cheikh Anta Diop, Dakar, Sngal)
