摘要
<i>Staphylococcus aureus</i> is a gram-positive pathogenic bacterium responsible for various infections including skin suppurations. Quinolones are sometimes used last in infections. The <i>Staphylococcus aureus</i> objective of this study was to determine the prevalence and assess the level of resistance to quinolones of <i>Staphylococcus aureus</i> trains isolated in the Hospital and University Center of Brazzaville (CHU-B). 40 strains of <i>Staphylococcus aureus</i> from various biological products were isolated and identified by bacteriological methods. The study of the resistance of these different strains to antibiotics (Quinolones/Fluoroquinolones) was carried out by the phenotypic method, by antibiogram. A total of 40 <i>Staphylococcus aureus</i> strains were isolated including 13 (32.50%) community strains, 27 (67.5%) clinical strains distributed as follows: neonatal and pediatric service 29.62% and 25.92%, surgery 18.51%, contagious 14.81%, emergencies 7.4% and delivery block 3.7%. 60% of strains were isolated in women and 40% in men. The average age of those infected was 16 years and older. 90% strains were resistant to Nalidixic acid (AN), 72.5% to Ofloxacin (OFL), 67.5% to Ciprofloxacin (CIP), 70% to Norfloxacin (NOR), 62.5% to Levofloxacin (LEV), 47.5% to Moxifloxacin (MXF), and 40% strains were resistant to all antibiotics tested.
<i>Staphylococcus aureus</i> is a gram-positive pathogenic bacterium responsible for various infections including skin suppurations. Quinolones are sometimes used last in infections. The <i>Staphylococcus aureus</i> objective of this study was to determine the prevalence and assess the level of resistance to quinolones of <i>Staphylococcus aureus</i> trains isolated in the Hospital and University Center of Brazzaville (CHU-B). 40 strains of <i>Staphylococcus aureus</i> from various biological products were isolated and identified by bacteriological methods. The study of the resistance of these different strains to antibiotics (Quinolones/Fluoroquinolones) was carried out by the phenotypic method, by antibiogram. A total of 40 <i>Staphylococcus aureus</i> strains were isolated including 13 (32.50%) community strains, 27 (67.5%) clinical strains distributed as follows: neonatal and pediatric service 29.62% and 25.92%, surgery 18.51%, contagious 14.81%, emergencies 7.4% and delivery block 3.7%. 60% of strains were isolated in women and 40% in men. The average age of those infected was 16 years and older. 90% strains were resistant to Nalidixic acid (AN), 72.5% to Ofloxacin (OFL), 67.5% to Ciprofloxacin (CIP), 70% to Norfloxacin (NOR), 62.5% to Levofloxacin (LEV), 47.5% to Moxifloxacin (MXF), and 40% strains were resistant to all antibiotics tested.
作者
Léa Gwladys Gangoue
Etienne Nguimbi
Faust René Okamba Ondzia
Briceline Princesse Banzouzi Mahoukou
Tantique Moutali Lingouagou
Tarcisse Baloki Ngoulou
Isaac Samuel Onyankouang
Rachel Moyen
Léa Gwladys Gangoue;Etienne Nguimbi;Faust René Okamba Ondzia;Briceline Princesse Banzouzi Mahoukou;Tantique Moutali Lingouagou;Tarcisse Baloki Ngoulou;Isaac Samuel Onyankouang;Rachel Moyen(Laboratoire de Biologie Cellulaire et Moléculaire (BCM), Faculté des Sciences et Techniques, Université Marien NGOUABI, Brazzaville, Congo;Unité de Microbiologie moléculaire et Bioinformatique, Faculté des Sciences et Techniques, Université Marien NGOUABI, Brazzaville, Congo;Institut National de Recherche en Sciences Exactes et Naturelles (IRSEN), Avenue de l’Auberge Gascogne Scientific City (Ex. OROSTOM), Brazzaville, Congo)