摘要
Background: The diagnosis of prostate cancer (PCa) relies on clinical assessment with digital rectal examination, serum PSA and histological examination. Limitations in our technical facilities, high financial cost of ultrasound-guided biopsy often prevent us from implementing the guidelines on the practice of prostate biopsy. Methods: We conducted a retrospective and cross-sectional descriptive study comparing digital-guided and ultrasound-guided transrectal prostate biopsy of 400 patients over a period of 12 years in the Yaounde Central Hospital. We reviewed files of patients who underwent digital and ultrasound guided biopsy procedures. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: Out of the 400 patients, 292 digital-guided transrectal biopsies (73%) and 108 ultrasound-guided transrectal biopsies (27%) were performed in patients who were suspected of having prostate cancer (PCa). Patients were aged between 39 to 90 years. Both procedures were effective in identifying prostate cancer. Gleason score between 2 to 10 detected prostate adenocarcinoma for 301 patients (75.2%). The complications included anal pain, rectal bleeding, hematuria and urinary tract infections, with an occurrence rate similar for both ultrasound-guided (2.25%) and digitally-guided techniques (2.5%). Seven patients (1.75%) required hospitalization for management of complications. The mortality rate was null. Conclusion: Both techniques are effective in detecting PCa with the similar complication rates. Digital-guided trans-rectal prostate biopsy still has its place in a resource-limited setting like ours.
Background: The diagnosis of prostate cancer (PCa) relies on clinical assessment with digital rectal examination, serum PSA and histological examination. Limitations in our technical facilities, high financial cost of ultrasound-guided biopsy often prevent us from implementing the guidelines on the practice of prostate biopsy. Methods: We conducted a retrospective and cross-sectional descriptive study comparing digital-guided and ultrasound-guided transrectal prostate biopsy of 400 patients over a period of 12 years in the Yaounde Central Hospital. We reviewed files of patients who underwent digital and ultrasound guided biopsy procedures. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: Out of the 400 patients, 292 digital-guided transrectal biopsies (73%) and 108 ultrasound-guided transrectal biopsies (27%) were performed in patients who were suspected of having prostate cancer (PCa). Patients were aged between 39 to 90 years. Both procedures were effective in identifying prostate cancer. Gleason score between 2 to 10 detected prostate adenocarcinoma for 301 patients (75.2%). The complications included anal pain, rectal bleeding, hematuria and urinary tract infections, with an occurrence rate similar for both ultrasound-guided (2.25%) and digitally-guided techniques (2.5%). Seven patients (1.75%) required hospitalization for management of complications. The mortality rate was null. Conclusion: Both techniques are effective in detecting PCa with the similar complication rates. Digital-guided trans-rectal prostate biopsy still has its place in a resource-limited setting like ours.
作者
Junior Barthelemy Mekeme Mekeme
Oriol Landry Mbouche
Figuim Bello
Bright Che Awondo
Aurele Achille Mbassi
Cedrick Jean Fouda
Tax Liendi
Marcella Biyouma
Guillaume Gayma
Marcel Junior Yon Mekeme
Junior Ngue Ngue
Mabah
Paul Adrien Atangana
Pierre Ongolo Zogo
Pierre Joseph Fouda
Noel Coulibaly
Angwafo III Fru
Maurice Aurelien Sosso
Junior Barthelemy Mekeme Mekeme;Oriol Landry Mbouche;Figuim Bello;Bright Che Awondo;Aurele Achille Mbassi;Cedrick Jean Fouda;Tax Liendi;Marcella Biyouma;Guillaume Gayma;Marcel Junior Yon Mekeme;Junior Ngue Ngue; Mabah;Paul Adrien Atangana;Pierre Ongolo Zogo;Pierre Joseph Fouda;Noel Coulibaly;Angwafo III Fru;Maurice Aurelien Sosso(Faculty of Medecine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon;Department and Urology and Andrology, Yaounde Central Hospital, Yaounde, Cameroon;Higher Institute Medical Technology, Yaounde, Cameroun;Anatomy and CytoPathology Laboratory “Centre Pasteur”, Yaounde, Cameroon;Felix Houphouet Boigny University of Cocody, Abidjan, Ivory Coast)
