摘要
Polycystic Ovary Syndrome (PCOS) is a common cause of infertility, requiring antioestrogen and, possibly, gonadotropin treatment for the induction of <span style="font-family:Verdana;">ovulation. However, patients suffering from this disease need long-term</span><span style="font-family:Verdana;"> treatment since PCOS is associated with an increased risk of metabolic syndrome, hyperinsulinemia, oxidative stress, inflammation, cardiovascular disease, and cancer. Allopathic treatment includes the continuous use of oral contraceptives, preferentially with complementary anti-androgen activity, and metformin. However, these treatments only partially correct all aspects of the disease, while carrying potential adverse effects </span><i><span style="font-family:Verdana;">per se</span></i><span style="font-family:Verdana;">. Complementary and alternative medicine (CAM) offers opportunities for treatment through the use of nutraceuticals containing plant extracts, minerals, and vitamins with antioxidant, anti-inflammatory, and adaptogen capacity, as well as for correcting insulin resistance. Here we justify the formulation of the nutraceutical QALY<span style="white-space:nowrap;"><sup>®</sup></span> (Jona Pharma, Elversele, Belgium) that is composed of Ubiquinone Q10, the vitamins B9 and B12, the salts of zinc and selenium, the biomass of </span><i><span style="font-family:Verdana;">Haematococcus pluvialis</span></i><span style="font-family:Verdana;">, and the extracts of Mediterranean pine bark and of </span><i><span style="font-family:Verdana;">Rhodiola rosea</span></i><span style="font-family:Verdana;">. This can be complemented by phytotherapy with the extract of </span><i><span style="font-family:Verdana;">Momordica charantia</span></i><span style="font-family:Verdana;"> plus alfa lipoic acid (Momordica plus<span style="white-space:nowrap;"><sup>®</sup></span>).</span>
Polycystic Ovary Syndrome (PCOS) is a common cause of infertility, requiring antioestrogen and, possibly, gonadotropin treatment for the induction of <span style="font-family:Verdana;">ovulation. However, patients suffering from this disease need long-term</span><span style="font-family:Verdana;"> treatment since PCOS is associated with an increased risk of metabolic syndrome, hyperinsulinemia, oxidative stress, inflammation, cardiovascular disease, and cancer. Allopathic treatment includes the continuous use of oral contraceptives, preferentially with complementary anti-androgen activity, and metformin. However, these treatments only partially correct all aspects of the disease, while carrying potential adverse effects </span><i><span style="font-family:Verdana;">per se</span></i><span style="font-family:Verdana;">. Complementary and alternative medicine (CAM) offers opportunities for treatment through the use of nutraceuticals containing plant extracts, minerals, and vitamins with antioxidant, anti-inflammatory, and adaptogen capacity, as well as for correcting insulin resistance. Here we justify the formulation of the nutraceutical QALY<span style="white-space:nowrap;"><sup>®</sup></span> (Jona Pharma, Elversele, Belgium) that is composed of Ubiquinone Q10, the vitamins B9 and B12, the salts of zinc and selenium, the biomass of </span><i><span style="font-family:Verdana;">Haematococcus pluvialis</span></i><span style="font-family:Verdana;">, and the extracts of Mediterranean pine bark and of </span><i><span style="font-family:Verdana;">Rhodiola rosea</span></i><span style="font-family:Verdana;">. This can be complemented by phytotherapy with the extract of </span><i><span style="font-family:Verdana;">Momordica charantia</span></i><span style="font-family:Verdana;"> plus alfa lipoic acid (Momordica plus<span style="white-space:nowrap;"><sup>®</sup></span>).</span>
作者
Comhaire Frank
Decleer Wim
Comhaire Frank;Decleer Wim(Ghent University Hospital, Consultant Endocrinologist, Fertility-Belgium Clinic, Aalter, Belgium;Head of Department of Reproductive Medicine AZ Jan Palfijn, Ghent, Belgium)
