摘要
慢性心力衰竭是多种心血管疾病发展至终末期的临床表现,心肌重构是慢性心力衰竭的早期代偿机制也是晚期慢性心力衰竭的主要病理基础,心肌重构的主要表现形式之一是心肌纤维化,治疗心肌纤维化是治疗慢性心力衰竭的重要手段,有助于改善预后。目前,治疗慢性心力衰竭的药物大多只能改善临床症状,不能针对心肌纤维化进行治疗。近年研究发现,中医药治疗心肌纤维化具有多层次、多靶点、不易引起电解质紊乱的优势,其疗效显著,相关基础实验研究已取得长足发展。本文就近三年中医药抑制慢性心力衰竭心肌纤维化的中医研究展开综述,以期为中医药临床防治慢性心力衰竭心肌纤维化提供实验依据,为临床相关治疗及研究提供一定的参考。
Chronic heart failure is a variety of cardiovascular disease to end-stage clinical manifestations of myocardial remodeling, is late early compensatory mechanism of chronic heart failure, is the main pathological basis of chronic heart failure;myocardial remodeling is one of the main forms of myocardial fibrosis, and therapy of myocardial fibrosis is an important means of treatment of chronic heart failure, helps to improve the prognosis. At present, most of the drugs used to treat chronic heart failure can only improve the clinical symptoms and cannot target the treatment of myocardial fibrosis. In recent years, it has been found that traditional Chinese medicine has the advantages of multi-level, multi-target, and not easy to cause electrolyte disorder in the treatment of myocardial fibrosis. Its curative effect is remarkable, and the relevant basic experimental research has made great progress. This article reviews the research of traditional Chinese medicine in the recent three years on the inhibition of myocardial fibrosis in chronic heart failure by traditional Chinese medicine, in order to provide experimental basis for the clinical prevention and treatment of myocardial fibrosis in chronic heart failure by traditional Chinese medicine, and provide certain reference for clinical related treatment and research.
出处
《中医学》
2022年第6期1019-1024,共6页
Traditional Chinese Medicine
