摘要
儿童脓毒症及脓毒性休克,是全球儿童死亡的主要原因之一,造成了巨大的疾病负担,本综述文章旨在探讨最新的儿童脓毒性休克诊断标准及治疗方法。儿童脓毒性休克诊断标准已由2024年国际共识更新,引入菲尼克斯脓毒症评分(Phoenix Sepsis Score, PSS)作为新的诊断工具,以提高对脓毒症和脓毒性休克儿童的识别准确性。治疗方面,本文讨论了液体复苏、血管活性药物、抗生素治疗、糖皮质激素应用以及支持性治疗等策略。其中液体复苏作为脓毒性休克管理的基石,而适当使用血管活性药物和抗生素治疗对于改善患儿预后同样至关重要。糖皮质激素的辅助治疗在特定情况下可考虑,而支持性治疗如呼吸和肾脏功能支持对于维持患儿生命体征稳定具有重要作用。
Pediatric sepsis and septic shock are one of the leading causes of death in children worldwide, resulting in a significant disease burden. This review article aims to explore the latest diagnostic criteria and treatment methods for pediatric septic shock. The diagnostic criteria for pediatric septic shock have been updated by the 2024 International Consensus, introducing the Phoenix Sepsis Score as a new diagnostic tool to enhance the accuracy of identifying children with sepsis and septic shock. In terms of treatment, this article discusses strategies including fluid resuscitation, vasopressor therapy, antibiotic treatment, the use of corticosteroids, and supportive care. Fluid resuscitation serves as the cornerstone of septic shock management, while the appropriate use of vasopressors and antibiotic treatment is equally essential for improving patient outcomes. Corticosteroid adjunct therapy may be considered under specific circumstances, and supportive care, such as respiratory and renal function support, plays a vital role in maintaining the stability of children’s vital signs.
出处
《临床医学进展》
2024年第4期1689-1694,共6页
Advances in Clinical Medicine
