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血清学标志物在胃癌诊断中的研究进展

Research Progress of Serological Markers in the Diagnosis of Gastric Cancer
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摘要 胃癌(GC)是我国常见的恶性肿瘤之一,其发病率和死亡率均居于我国恶性肿瘤第三位。目前胃癌诊断的金标准是胃镜与活体组织联合检查,但其毕竟为侵入性检查,存在一定痛苦和风险,患者接受程度较差,因此胃镜筛查在人群中的大规模开展受到了限制。用于协助诊断胃癌的方法还有PET-CT,增强CT,肿瘤相关标志物等检查。但其较高的费用及较为繁琐的检查过程使其并不能广泛应用于临床。血清学检查具有非侵入性、微创性的特点,在胃癌诊断检测更加方便、经济、安全,适用于高风险人群筛查,现将血清学指标在胃癌诊断中的研究进展进行综述。 Gastric cancer (GC) is one of the common malignant tumors in China, and its incidence and mortality are the third malignant tumors in China. At present, the gold standard for the diagnosis of gastric cancer is the combined examination of gastroscopy and living tissue, but after all, it is an invasive examination, which has certain pain and risk, and the acceptance of patients is poor, so the large-scale development of gastroscopy screening in the population is limited. PET-CT, enhanced CT, tumor related markers and other examinations are also used to assist in the diagnosis of gastric cancer. However, its high cost and cumbersome examination process make it not widely used in clinic. Serological examination has the characteristics of non-invasive and minimally invasive. It is more convenient, economical and safe in the diagnosis and detection of gastric cancer. It is suitable for screening in high-risk population. This paper reviews the research progress of serological indi-cators in the diagnosis of gastric cancer.
出处 《临床医学进展》 2024年第1期1310-1316,共7页 Advances in Clinical Medicine
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