摘要
支气管肺发育不良(bronchopulmonary dysplasia, BPD)是一种以肺泡简单化、肺微血管发育障碍,伴随肺间质纤维化、肺不张及囊性变为病理特征的早产儿常见慢性肺部疾病。随着早产儿存活率的提高,BPD发生率也有逐年上升的趋势,BPD可导致慢性心肺及神经系统后遗症,严重影响早产儿的存活率及远期生存质量,成为NICU最为棘手的问题之一。近年来越来越多的文献报道解脲脲原体(Ureaplasma urealyticum, UU)的感染与BPD的发生发展有关,本文就支气管肺发育不良与解脲脲原体的关系的研究进展进行综述。
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in preterm infants charac-terized by alveolar simplicity, pulmonary microvascular dysplasia, and pulmonary interstitial fi-brosis, atelectasis, and cystic transformation. As the survival rate of preterm infants increases, the risk of cardiac arrest increases. The incidence of BPD also has an increasing trend year by year. BPD can lead to chronic cardiopulmonary and nervous system sequelae, seriously affecting the survival rate and long-term quality of life of premature infants, and becoming one of the most intractable problems in NICU. In recent years, more and more literatures have reported that Ureaplasma urea-lyticum (UU) infection is related to the occurrence and development of BPD. In summary, this paper reviews the research progress on the relationship between bronchopulmonary dysplasia and Urea-lyticum.
出处
《临床医学进展》
2024年第1期160-167,共8页
Advances in Clinical Medicine
