摘要
早发冠心病以起病较急、无先兆、预后较差为特点。随着冠心病发病年轻化,早发冠心病患者人群也在增加,糖尿病(diabetes mellitus, DM)容易加速动脉硬化与损伤进程,促进冠状动脉病变,导致冠心病(coronary heart disease, CHD),与单纯冠心病患者相比,合并糖尿病者冠状动脉病变更加弥漫而严重。本文通过早发冠心病合并2型糖尿病的诊断要点及相关的循证研究,从流行病学、危险因素、死亡率、发病机制等不同角度进行综述,并结合临床。以期为早发冠心病合并2型糖尿病的管理与防治提供思路。
Premature coronary heart disease is characterized by a more rapid onset, no aura, and a poorer prognosis. As the incidence of coronary heart disease becomes younger, the number of patients with premature coronary heart disease is also increasing. Diabetes mellitus (DM) can easily accelerate the process of atherosclerosis and damage, and promote coronary artery disease, leading to coro-nary heart disease (CHD), and compared with patients with pure coronary heart disease, coronary artery disease in patients with diabetes mellitus is more diffuse and severe. In this paper, we re-view the diagnostic points of premature coronary heart disease combined with type 2 diabetes mellitus and related evidence-based studies from different perspectives, such as epidemiology, risk factors, mortality, pathogenesis, etc., and combine them with clinical practice. In order to provide ideas for the management and prevention of type 2 diabetes mellitus combined with premature coronary heart disease.
出处
《临床医学进展》
2023年第9期14043-14048,共6页
Advances in Clinical Medicine
