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妊娠期亚临床甲状腺功能减退的研究进展

Research Progress of Subclinical Hypothyroidism in Pregnancy
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摘要 妊娠期亚临床甲状腺功能减退是常见的妊娠期甲状腺疾病,没有明显特异性表现,临床诊断只能靠实验室检查。目前关于妊娠期亚临床甲状腺功能减退是否会增加与流产、早产等不良妊娠结局和妊娠期糖尿病、妊娠期高血压等妊娠期并发症发生率,影响子代神经智力发育仍存在争议,仍需更多更大规模设计严密的前瞻性试验研究来提供证据支持。本文通过对妊娠期影响甲状腺功能的因素、诊断标准、母儿结局及治疗相关研究进展进行综述。 Subclinical hypothyroidism in pregnancy is a common thyroid disease in pregnancy with no obvious specific manifestations, and clinical diagnosis can only be made by laboratory examination. At pre-sent, it is still controversial whether subclinical hypothyroidism in pregnancy will increase the in-cidence of adverse pregnancy outcomes such as abortion and preterm birth, and the incidence of gestational complications such as gestational diabetes and gestational hypertension, and affect the neurointelligence development of offspring. More and larger scale well-designed prospective trial studies are still needed to provide evidence support. In this paper, the factors affecting thyroid function during pregnancy, diagnostic criteria, maternal and infant outcomes and treatment related research progress were reviewed.
出处 《临床医学进展》 2023年第9期13894-13900,共7页 Advances in Clinical Medicine
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