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进展期胃癌分子靶向治疗的进展

Molecular Targeting Therapy for Advanced Gastric Carcinoma
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摘要 进展期胃癌根治术后均需化疗,但是单纯化疗起到的姑息治疗的效果并不乐观。而胃癌对放疗的敏感性不高,所以较少使用放疗。随着多学科综合治疗模式的形成和分子靶向治疗的研发,分子靶向治疗在进展期胃癌的治疗具有一定的效果。本文主要介绍了靶点及相关靶向药物的应用,包括肝细胞生长因子、人表皮生长因子、成纤维细胞生长因子、血管内皮生长因子、人类表皮生长因子。 Chemotherapy is required after radical resection of advanced gastric cancer, but the effect of pallia-tive treatment by chemotherapy alone is not optimistic. However, gastric cancer is not sensitive to radiotherapy, so radiotherapy is seldom used. With the formation of multidisciplinary comprehen-sive therapy model and the research and development of molecular targeted therapy, it has a cer-tain effect in the treatment of advanced gastric cancer. This article mainly introduces the applica-tion of targets and related targeted drugs, including hepatocyte growth factor, human epidermal growth factor, fibroblast growth factor, vascular endothelial growth factor and human epidermal growth.
出处 《临床医学进展》 2023年第7期12155-12163,共9页 Advances in Clinical Medicine
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