摘要
来自细胞外囊泡的微RNA (miRNA),长度约为22个核酸,不参与单链RNA的编码。它们参与调节转录后的基因表达,并在调节免疫系统方面发挥重要作用。近些年,很多关于miRNA与结核病之间的研究表明miRNA在结核病的发生发展上发挥重要作用,为结核病的诊断与鉴别诊断以及发病机制的研究提供了潜在的可能。本文将针对外泌体来源的miRNA在肺结核诊断中的研究现状做一个综述。
miRNAs from extracellular vesicles are a class of substances that do not encode single stranded RNA, with a length of approximately 22 nucleic acids. They participate in regulating gene expression af-ter transcription and play an important role in regulating the immune system. In recent years, many studies on the relationship between miRNA and tuberculosis have shown that miRNA plays an important role in the occurrence and development of tuberculosis, providing potential possibili-ties for the diagnosis and differential diagnosis of tuberculosis and the study of pathogenesis. This article provides a review of the current research status of miRNAs derived from extracellular vesi-cles in the diagnosis of pulmonary tuberculosis.
出处
《临床医学进展》
2023年第7期11462-11467,共6页
Advances in Clinical Medicine
