摘要
卵巢癌的致死率居妇科恶性肿瘤首位,患者的远期生存率低,开发高效、低毒的新药物对于卵巢癌治疗具有重要意义。近年来,越来越多的研究发现了天然黄酮类化合物杨梅素的抗肿瘤活性,杨梅素通过诱导肿瘤细胞凋亡、抑制增殖和迁移侵袭、提高化疗敏感性等多种机制发挥抗肿瘤作用。本文就杨梅素在卵巢癌中的研究进展进行阐述,为天然产物的临床应用提供科学依据。
Ovarian cancer is the gynecological malignant tumor with the highest fatality rate, and the long-term survival rate of patients is low. The development of new drugs with high efficiency and low toxicity is of great significance for the treatment of ovarian cancer. In recent years, more and more studies have found the anti-tumor activity of natural flavonoids myricetin, which plays an an-ti-tumor effect by inducing tumor cell apoptosis, inhibiting proliferation, inhibiting migration and invasion, improving chemotherapy sensitivity, and so on. This paper reviews the research progress of myricetin in ovarian cancer in order to provide scientific basis for the clinical application of natu-ral products.
出处
《临床医学进展》
2023年第7期10996-11001,共6页
Advances in Clinical Medicine
