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心外膜在心肌损伤后心肌再生中的作用

The Role of Epicardium in Myocardial Regeneration after Myocardial Injury
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摘要 心外膜由单层间皮细胞组成,它覆盖了心脏的最外层,它的完整性和功能对于心脏的正常发育至关重要。作为血管生成和肌源性信号的中心,以及发育心脏中间充质细胞和心肌细胞的来源,心外膜具有在心肌梗塞后重新激活成熟心脏的巨大潜力,这引起了人们对心外膜及其在心肌损伤后再生作用的极大兴趣。 The epicardium is composed of monolayer mesothelial cells, which cover the outermost layer of the heart, and its integrity and function are essential for the normal development of the heart. As a center for angiogenesis and myogenic signaling, as well as a source of developing heart mesenchymal cells and cardiomyocytes, the epicardium has great potential to reactivate a mature heart after myocardial infarction, which has raised great interest in the epicardium and its regen-erative role after myocardial injury.
出处 《临床医学进展》 2022年第12期11928-11935,共8页 Advances in Clinical Medicine
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