摘要
目的:观察罗沙司他早期对肾性贫血患者促红细胞生成素(EPO)及网织红细胞参数影响,分析其在改善肾性贫血方面的有效性。方法:选取符合研究标准的受试者30名,在服药前及服药7天后分别抽取静脉血监测EPO及网织红细胞计数。结果:服药后患者EPO及网织红细胞计数显著升高,与服药前相比均有统计学意义P < 0.05。结论:罗沙司他可以在用药早期通过升高EPO浓度,加快成熟红细胞的增殖、分化,进一步改善肾性贫血患者贫血症状。
Objective: To observe the effect of rosastat on erythropoietin (EPO) and reticulocyte parameters in patients with renal anemia in the early stage, and analyze its effectiveness in improving renal anemia. Methods: Thirty subjects who met the study criteria were selected, and venous blood samples were taken before and 7 days after administration to monitor EPO and reticulocyte count. Results: The EPO and reticulocyte count of the patients increased significantly after taking the drug, which was statistically significant compared with that before taking the drug (P < 0.05). Conclusion: Rosalistat can accelerate the proliferation and differentiation of mature red blood cells by increasing EPO concentration at the early stage of administration, and further improve the anemia symptoms of patients with renal anemia.
出处
《临床医学进展》
2022年第12期11362-11367,共6页
Advances in Clinical Medicine
