摘要
进展期结直肠腺瘤(advanced colorectal adenoma, ACA)是结直肠癌(colorectal cancer, CRC)的重要前体,大多数CRC都是从腺瘤演变而来,而且ACA的恶变率更高。近年来,化学预防再一次成为热点话题,力争早期积极有效控制腺瘤的进一步发展和减少复发。目前ACA有关化学预防有非甾体抗炎药、他汀类及胆酸类药物,本文就ACA的化学预防相关药物作一综述。
Advanced colorectal adenoma (ACA) is an important precursor of colorectal cancer. Most colorectal cancers (CRC) evolve from adenomas, and ACA has a higher rate of malignant transformation. In re-cent years, chemoprevention has once again become a hot issue, striving to actively and effectively control the further development of adenomas and reduce recurrence in the early stage. At present, there are non-steroidal anti-inflammatory drugs, statins and bile acids related to ACA chemopre-vention. This article reviews the chemoprevention related drugs of ACA.
出处
《临床医学进展》
2022年第6期5142-5148,共7页
Advances in Clinical Medicine
