摘要
新生儿重症监护室新生儿尤其早产儿因为发育不成熟,免疫力低下,再加上PICC等侵入性诊疗措施多,广谱抗生素使用等因素并存,真菌感染发生率明显高于普通病房。真菌感染缺乏特异的临床表现,早期诊断困难,病死率、致残率高。本文就NICU新生儿PICC相关的真菌感染现状、发病机制、诊断、预防及治疗做一综述。
The incidence of fungal infection in neonatal intensive care unit is significantly higher than that in general wards due to immature development of neonates, especially premature infants, low im-munity, more invasive diagnosis and treatment measures such as PICC and the use of broad-spectrum antibiotics. Fungal infection lacks specific clinical manifestations, early diagnosis is difficult, and mortality and disability are high. This article reviews the status about pathogenesis, diagnosis, prevention and treatment of PICC related fungal infections in NICU neonates.
出处
《临床医学进展》
2018年第10期875-881,共7页
Advances in Clinical Medicine
