摘要
目的 研究危重病监护病房 (ICU)内严重乳酸性酸中毒的病因、临床特征、治疗方法、影响预后的因素。方法 对我院ICU 2 0 0 0 - 0 6～ 2 0 0 3- 12收治的 2 3例严重乳酸性酸中毒患者的临床资料做回顾性分析。结果 基础病以严重感染多见 ,临床表现有低血压休克的患者 18例 (占 78.2 % ) ;患者平均血乳酸水平为 18.2 2mmol/L ,血乳酸水平与APACHEⅡ评分呈正相关 (r =0 .75 4 ) ,生存组与死亡组APACHEⅡ评分有显著性差异 ;血液净化组患者的APACHEⅡ评分显著高于常规治疗组 ,但两组的死亡率无显著差异。结论 导致严重乳酸性酸中毒的最常见病因是休克和循环衰竭 ;患者血乳酸水平和病情危重程度呈正相关 ,是影响预后的重要因素 ;
Objective To study inducement, clinical characteristic, treatment and prognosis of serious lactic acidosis. Methods A total of 23 cases with serious lactic acidosis in intensive care unit from June 2000 to December 2003 were studied retrospectively. Results The common primary disease was serious infection, 18(78.2%) patients showed hypotension; The average level of lactic acid in plasma was 18.22 mmol/L, the level of lactic acid in plasma was positively correlative with APACHEⅡ score ( r =0.754), APACHEⅡ score in survival group was significantly different from death group; APACHEⅡ score in blood purify group was significantly higher than normal group, the rate of death in two groups had no significant difference. Conclusions The common inducement of serious lactic acidosis in intensive care unit was shock and circulation failure; the level of lactic acid in plasma was positively correlative with serious degree of illness and was an important factor that can affect prognosis of patient; the blood purify may be the best treatment for serious lactic acidosis.
出处
《中国急救医学》
CAS
CSCD
北大核心
2004年第6期405-406,共2页
Chinese Journal of Critical Care Medicine
