摘要
目的 了解小剂量多巴胺持续静点辅助治疗各种原因造成的儿童急性肾功能衰竭 (ARF)的疗效。方法 选择我科 1999年 6月 -2 0 0 3年 6月住院急性肾功能衰竭病人 70例 ,随机分为两组 ,治疗组在常规治疗的基础上使用持续小剂量多巴胺 ( 2 -5ug kg 分 )静点 45 -160小时 ,并与对照组进行比较。结果 发现使用多巴胺组后在尿量增加、临床症状好转、血肌酐下降程度及内生肌酐清除率回升等肾功能恢复指标与对照组比较有显著差异。讨论 多巴胺具有改善肾血供 ,增加肾滤过率 ,促进利尿 ,对肾功能的恢复有明显疗效 ,不失是一种辅治ARF的好方法 ,在基层无条件做血透或腹透时采用此方法保守治疗值得推广。
Objective To understand the clinical effect of using a small dose dopamine intravenously in the treatment of ARF facilitialy.Methods We selected 70 ARF cases hospitalized in our hospital from the June of 1999 to the june of 2003 and grouped into two parts at random. The subjective group treated with a small dose dopamine(2-5ug/kg/m)for 45 hours to 160 hours intravenously under the condition of geven normal medication and compared with the control group.Results Clinical findinds show that perameters of kidney function of the subjective group are remarkablely differene compared with the control group,like the increase of urine,improved clinical health condition,decrease of blood creasine and the a gained elevation of blood creasine clearence,etc.Conclusions Dopamine has an ability to promote the blood provide of kidney ,increase the permeability rate,enchance the diuresis and has a good effect on the recover of kidney function, and it is a quite good additional method for the treatment of ARF in some places where are no enough advanced medical technology and equipments,such as peritoneal dialysis and haemodialysis.
出处
《海南医学》
CAS
2004年第7期4-5,共2页
Hainan Medical Journal
