摘要
目的 探讨肾功能不全不同阶段患者血甲状旁腺激素(PTH)的变化及与血钙、血磷、血红蛋白的关系。方法 测定56例肾功能不全不同阶段患者的血肌酐、尿素氮、血PTH、血钙、血磷、血红蛋白。结果 氮质血症组与正常对照组相比 ,血钙、血磷正常 (P>0.05) ,血PTH升高(P<0.001)。尿毒症组与氮质血症组比较 ,血钙降低(P<0.05) ,血磷升高(P<0.05) ,血PTH更高(P<0.02)。血PTH与血钙呈负相关、与血磷呈正相关 ,与血红蛋白呈负相关。结论 肾功能不全患者血钙、血磷是血PTH升高的主要因素 ,同时血PTH又作为一种尿毒素导致贫血的发生。
Objective To explore the relation between the change of parathyroid hormone(PTH)and serumcalcium(Ca),phosphorum(P)and hemoglobin(Hb)in patients of different stage in chronic renal dysfunction. Methods To assay serum Cr、BUN、PTH、Ca、P、Hb of56patients of different stage in chronic renal dysfunction. Result The levels of serum Ca and P were normal(P>0.05)and serum PTH were higher(P<0.001)in patients of azotemia group compared to those of normal group.The levels of serum Ca were less(P<0.05),serum P were higher(P<0.05)and serum PTH were higher(P<0.02)in patients of uremia group compared to those of azotemia group.In patients of chronic renal dysfunction,the levels of serum PTH were negative correlative with serumCa and Hb,but were positive correlative with P. Conclusion In patients of chronic renal dysfunction,serumCa and P play an important role in elevation of serum PTH,and as a uremic toxin,PTH result in anemia.
出处
《浙江临床医学》
2004年第5期365-365,367,共2页
Zhejiang Clinical Medical Journal
关键词
慢性肾功能不全
甲状旁腺激素
血钙
血磷
血红蛋白
测定
Chronic renal dysfunction,Parathyroid hormone(PTH),Serum calcium(Ca),Serum phosphorum(P),Hemoglobin(Hb)
