摘要
用羟磷灰石放射分析法分析了家兔心肌胞浆、胞核雌、雄激素受体的特性表明家兔心房肌胞浆、胞核<sup>3</sup>H-E<sub>2</sub>特异结合部位具有可饱和性、低容量和高亲和力、甾体特异性和稳定结合等特性,因而证实家兔心房存在雌激素受体。心室因无上述受体基本特性而证实无雌激素受体存在;家兔心房肌和心室肌胞浆、胞核<sup>3</sup>H-T 特异结合部位也具备上述受体基本特性,证实有雄激素受体存在.
The observation that cardioatrium,but not ventricle,possesses estrogen receptors by using the radioligand binding assay was reported.The estrogen receptors in rabbit atrium showed its characteristic as follows:(1)can be saturated,had limited capacity and with high affinity;(2)had high steroid specificity;(3)readily binding.Androgen receptors of rabbit cardioatrium and ventricle also showed the above mentioned characteristics.
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
1992年第4期25-29,共5页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
暨南大学青年科研基金资助课题
关键词
雌激素
雄激素
受体
放射受体分析
estrogen receptors
androgen receptors
rabbit atrium
rabbit ventricle
radioligand binding assay
