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干扰素对秋季腹泻的疗效观察 被引量:12

Observing the curative effect of interferon on autumn diarrhea
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摘要 目的 :探讨秋季腹泻有效的治疗措施。方法 :将秋季腹泻患儿 80例随机分为治疗组与对照组各 4 0例。治疗组加用α-干扰素 5万单位 / kg肌注 ,每日一次 ,连用 3d。对照组仅用双黄连、利巴韦林静滴等常规治疗。结果 :72 h止泻率治疗组为 95 .0 % ,对照组为 72 .5 % (P<0 .0 1)。治疗组与对照组止泻时间分别为 39.5± 13.6 h和 5 2 .5± 14 .9h(P<0 .0 1) ,两组比较有显著性差异。结论 :干扰素治疗秋季腹泻在病程和病情改善方面均优于其他抗病毒药 ,值得临床推广。 Objective:To search for the effective therapy of autumn diarrhea. Methods: 80 children patients with autumn diarrhea were randomly divided into two groups, therapy group with 40 cases and control group with 40 cases, Using interferonα- 50 thousand IU/kg intramuscular injection in therapy group once a day for 3 days while ShuangHuangLian & ribavirin added into 100~150 ml 10% G.S solution , interavenous drip in control group, once a day. Results: The rate of stopping diarrhea within seventy-two hours is 95% in therapy group and 72.5% in control (P<0.01). The time of stopping diarrhea is respectively 39.5±13.6 and 52.5±14.9 hours in the two groups. There is a significant difference between the two groups (P<0.01).Conclusion: Interferon-α in treating autumn diarrhea is better than the other antivirus drugs in the course and development of the case, and is worthy of application.
出处 《中国妇幼保健》 CAS 2004年第4期50-51,共2页 Maternal and Child Health Care of China
关键词 干扰素 秋季腹泻 小儿 药物治疗 Interferon-α Autumn diarrhea Infants
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