摘要
目的 观察静脉曲马多与芬太尼在口腔颌面部手术后镇痛的临床效果及不良反应。方法 ASAⅠ～Ⅱ级 6 0例择期行口腔颌面部手术病人 ,随机分为两组 ,曲马多组 (T组 )和芬太尼组(F组 ) ,每组 30例。T组 :曲马多 4 0 0mg+芬太尼 0 4mg +氟哌利多 2 5mg;F组 :芬太尼 2 0mg +氟哌利多 2 5mg ,均以生理盐水配置 10 0ml药袋 ,给予负荷剂量 4ml后连接ACEMedical镇痛泵进行自控镇痛 (PCA)。术后行 2、8、2 0、4 4hVAS评分 ,并对有效按压次数、用药量及不良反应发生情况进行了观察比较。结果 两组VAS评分、有效按压次数、用药量均无显著差异 (P >0 0 5 ) ,不良反应发生率F组明显高于T组。结论 曲马多与芬太尼联合应用于口腔颌面部手术的术后镇痛与芬太尼单独应用效果相当 ,但不良反应发生率明显低于后者 ,是一种更安全。
Objective To study the balance analgesia efficacy and side effects of tramadol and fentanyl postoperation of oral or jew and face.Methods Sixty ASA Ⅰ-Ⅱ patients were randomly divided into two groups ,tramadol group(group T) and fentanyl group(group F).Tramadol group (n=30) received tramadol 400mg+fentanyl 0.4mg +dropridol 2.5mg. Fentanyl group (n=30) received fentanyl 2.0mg+droperidol 2.5mg. The visual analgesia scale (VAS) was assessed at 2,8,20,44hours after operation. Drugs dose and availability press times were compared and side effects was observed such as dizzy,nausea and sedation was observed. Results VAS and drugs dose were significantly difference in two groups (P>0.05). But side-effects were significantly increased in group F compared with those in group T.Conclusion The analgesia efficacy of tramadol combined with fentanyl was same as fentanyl after oral or jaw and face operation, but side effects were significantly increased in group F, group T was more safty and handly.
出处
《临床麻醉学杂志》
CAS
CSCD
2004年第5期271-273,共3页
Journal of Clinical Anesthesiology
