期刊文献+

活性氧与血管内皮细胞的信号转导 被引量:3

下载PDF
导出
摘要 一定量的活性氧 (ROS)可作为血管内皮细胞内信号转导分子 ,通过作用于细胞内相关靶分子 ,调节细胞生长、凋亡和生存的相关基因 ,从而对生理和病理生理情况下血管自稳调节起重要作用。
出处 《国外医学(生理病理科学与临床分册)》 2004年第2期153-155,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金 云南省自然科学基金资助项目 (C2 10 0 47M)
  • 相关文献

参考文献20

  • 1Droge W.Free radicals in the physiological control of cell function [ J ].Physiol Rev ,2002,82(1):47-95. 被引量:1
  • 2Cai H,Harrison DG.Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress [ J ].Circ Res,2000,87 (10): 840-844. 被引量:1
  • 3Clark RA.Activation of the neutrophil respiratory burst oxidase [J].J Infect Dis,1999,179(Suppl 2):S309-S317. 被引量:1
  • 4Gorlach A,Brandes RP,Nguyen K,et al.A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall [ J ].Circ Res,2000,87(1):26-32. 被引量:1
  • 5Vasquez-Vivar J ,Kalyanaraman B ,Martasek P,et al.Superoxide generation by endothelial nitric oxide synthase:the influence of cofactors[ J].Proc Natl Acad Sci USA,1998,95 (16):9220-9225. 被引量:1
  • 6Kerr S,Brosnan M J,McIntyre M,et al.Superoxide anion production is increased in a model of genetic hypertension: role of endothelium [ J ].Hypertension,1999,33 (6): 1353-1358. 被引量:1
  • 7Nakazono K,Watanabe N,Matsuno K,et al.Does superoxide underlie the pathogenesis of hypertension? [ J ].Proc Natl Acad Sci USA,1991,88 (22): 10045-10048. 被引量:1
  • 8Suzuki H,Swei A,Iweifach BW,et al.In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: hydroehidine microfluorography [ J].Hyprtension,1995,25 (5): 1083-1089. 被引量:1
  • 9Schachinger V,Britten MB,Zeiher AM.Prognostic impact of coronary vasdilator dysfunction on adverse long-term outcome of coronary heart disease[J].Circulation,2000,101(16):1899-1906. 被引量:1
  • 10Kunch C,Medford RM.Oxidative stress as a regulator of gene expression in the vasculature [ J ].C irc Res,1999,85 (8):753-766. 被引量:1

同被引文献24

引证文献3

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部