摘要
目的 检查非法生产的枸橼酸西地那非原料和非法加入补肾壮阳中成药及性保健药品中的枸橼酸西地那非。方法 建立化学分离方法,从高效液相色谱法初步确认含有枸橼酸西地那非的原料药、中成药及性保健品中分离提取西地那非,并用中红外分光光度法(溴化钾压片)进行定性鉴别。结果 对高效液相色谱法检测含有西地那非的28批原料、62批各种剂型的中成药,进行红外鉴定,均检出含有西地那非。结论 该方法专属性强,快速,简便。
OBJECTIVE To identify sildenafile in medicinal substances produced and in traditional Chinese medicines mixed illegally. METHODS Chemical methods were established to separate sidenafile from traditional Chinese medicines, and the medicinal substances and residues extracted were identified by IR. RESULTS Twenty-eight batches of raw materials and 62 batches of different dosages of Chinese patent drugs were found to contain sidenafile. CONCLUSIONS The method is specific, quick and convenient.
出处
《中南药学》
CAS
2004年第3期144-146,共3页
Central South Pharmacy
关键词
西地那非
原料
中成药
制剂
红外光谱
鉴别
化学成分
medicinal substance
traditional Chinese medicine preparation
sildenafile
IR
chemical separation
