摘要
目的 研究弥散加权成像 (DWI)及表观弥散系数 (ADC)像在鉴别胶质瘤、转移瘤及脑脓肿中的应用 ,观察病变中心的坏死、瘤周水肿的ADC值对三者的鉴别诊断价值。资料与方法 搜集 5 0例颅内单发环形强化病变 ,所有病例均行平扫、增强及DWI检查。其中胶质瘤 2 0例 ,脑脓肿 10例 ,单发转移瘤 2 0例。分别计算病变的中心坏死区、周围水肿、对侧正常脑实质及脑脊液的ADC值 ,用方差分析法比较不同病变的坏死灶与脑脊液、周围水肿与正常脑实质的ADC值有无差别。结果 脑脓肿、转移瘤及胶质瘤中心坏死区的ADC值间均有统计学差异 ,而且三者与脑脊液的ADC值亦有统计学差异。中心坏死区与脑脊液的ADC值从大到小为 :脑脊液、胶质瘤、转移瘤和脑脓肿。脑脓肿和转移瘤周围水肿的ADC值间无统计学差异 ,二者与胶质瘤周围水肿均有统计学差异 ,后者的ADC值低于前二者。水肿区的ADC值明显高于正常脑实质。
Objective To evaluate diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) in differentiating cerebral glioma, solitary metastasis and abscess. Materials and Methods Fifty cases with intracranial solitary lesions which displayed circular enhancement were enrolled in this study. Both plain and enhanced MR scanning, as well as DWI were performed in all cases. The lesions included glioma (n=20), abscess (n=10) and solitary metastasis (n=20). ADC values of the central necrosis, surrounding edema, and cerebral parenchyma and CSF of the normal side were separately calculated, and the results were compared between different lesions.Results Significant difference in ADC value of central necrosis existed among glioma, metastasis and abscess, and the above values were also statistically different from the ADC value of CSF. The value of ADC from high to low was seen in the following order: CSF, glioma, metastasis and abscess. ADC values of the surrounding edema showed no statistic difference between abscess and metastasis, nevertheless, the values of the above two lesions were significantly higher than that of glioma. ADC value at edema area was markedly higher than that of normal cerebral parenchyma. Conclusion Both DWI and ADC are of great value in differentiating intracranial lesions which display circular enhancement.
出处
《临床放射学杂志》
CSCD
北大核心
2004年第5期375-378,共4页
Journal of Clinical Radiology
