摘要
本实验应用均相酶免疫法和PKBP—N_1程序包对六名健康志愿者分别口服三种茶碱缓释剂后的药动学参数和相对生物利用度进行了探讨,结果表明:三者的生物利用度、吸收速率常数和波动百分率均无显著差异(P>0.05)。
Emit and PKBP_(Nl) program were used for the pharmacokinetics and bioavailability study on three sustained-releasetheophylline tablets in six healthy volunteers. The results showed that there were no significant difference (P>0.05) amongthree tablets on AUC, Ka and the change percentage of theophylline serum level.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1992年第10期440-442,共3页
Chinese Journal of Hospital Pharmacy
关键词
茶碱
缓释剂
生物利用度
sustained-release theophylline tablet
bronchus asthma
pharmacokinetics
bioavailability
