摘要
目的探讨高温高湿创伤复合应激条件下醛固酮的变化规律 ,为研究提高部队应对应激反应的能力提供实验依据。方法 (1 )湿热创伤非给药组动物以去离子水灌胃 1周 ,造成背部浅Ⅱ°烫伤 ,置于仿真模拟气候舱 (干球温度 37± 0 .5℃ ,相对湿度 6 5 %± 5 % ) 1～ 2h ,每组各分为热应激 1h、2h、4h、1 0h四个时相点 ;(2 )湿热创伤给药组给予维生素C、L 精氨酸、维生素E组成的复合营养素灌胃 1周 ,创伤和湿热、时相点处理同 (1 )。结果湿创对照组和给药组血清ALD含量变化的差异有显著性意义 (P <0 .0 5 )。对照组 6h、1 2h血清ALD含量与 1h比较差异有显著意义 (P <0 .0 1 )。结论ALD的含量变化与机体的生理病理改变具有密切关系 。
Objective To study into the changes of rat serum ALD at moist heat and wound stress in order to build a basis for research of enhancing resistance to stress response in soldiers. Methods The rats were divided into 2 groups, each group divided into 4 period of time, in the humid heat and wound stress control group, imbue with double-distilled water for one week ;in the humid heat and wound stress treated group, imbue with ascorbic acid and L-arginine mixed with α-Tocopherol for one week ;were exposed to the same conditions for 1～2h: T 37± 0.5℃ and relative humidity65%±5%. Results The differences of ALD changes between the 2 groups were significant ( P <0.05). The differences of ALD changes between the control group at 1h and control group at 6h, 12h were significant ( P <0.01). Conclusion The change of ALD is related with body's Physiology and Pathology. If took effective intervene measures early, would restrained and alleviated the damage of body. It will be useful for strengthening organism's adaptability to stress to observe dynamic changes and intervene in time.
出处
《护士进修杂志》
北大核心
2004年第4期296-298,共3页
Journal of Nurses Training
基金
全军医药卫生科研基金面上项目(0 1MA1 33)
关键词
湿热环境
高温环境
创伤
醛固酮
Moist heat Hot temperature environment Trauma ALD
