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心肌肌钙蛋白I与急性心肌梗死患者近期预后的关系 被引量:1

The Relationship of Cardiac Troponin I and the Prognosis of Acute Myocardial Infarction
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摘要 目的 探讨急性心肌梗死 (AMI)患者血清心肌肌钙蛋白I(cTnI)水平与近期预后的关系。方法 测定 5 1例AMI患者的血清cTnI,根据cTnI水平分为二组 ,观察住院期间心力衰竭、缺血性胸痛、心脏性死亡的发生率 ,测定左心室射血分数 (LVEF) ,分析cTnI水平与它们的关系。结果 在 5 1例AMI患者中 ,cTnI较高组 2 9例 ,较低组 2 2例 ,住院期间发生心力衰竭为 4 1 38%相对于 9 0 9% ,(P <0 0 1) ,缺血性胸痛为 4 4 83%相对于 18 18% ,(P <0 0 5 ) ,心脏性死亡为 3例相对于 0例 ,LVEF为 4 8%± 12 %相对于 5 8%± 12 % ,(P <0 0 5 ) ,存在显著差异。结论 血清cTnI是AMI患者住院期间预后的独立预测因子。 Objective To investigate the relationship of Cardiac Troponin I (cTnl) and the prognosis in patients with acute myocardial infarction (AMI). Methods Serum cTnI in 51 patients with AMI was measured. According to cTnI level (normol level is 0-0.15ug/dl), 51 patients were divided into two groups: A group (cTnI>10ug/dl) 29 cases and B group (cTnI 0.15—10ug/dl) 22 cases. Heart failure, ischemic chest pain, cardiac death and left ventricle ejection fraction (LVEF) were observed in patients of two groups during hospitalization. Relationship of cTnl level and the prognosis were analyzed in these two groups. Results During hospitalization, heart failure, ischemic chest pain, cardiac death occurred more often in group A than those in group B (41.38% vs 9.09%,P<0.01;44.38% vs 18.18%,P<0.05;3 Patients vs 0);and LVEF is lower in group A than that in group B (48%±12% vs 58%±12%,P<0.05).Conclusions Serum cTnI could be an independent indicator for the prognosis during hospitalization in patients with AMI.
机构地区 黄山市人民医院
出处 《心脑血管病防治》 2004年第2期15-17,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词 心肌肌钙蛋白Ⅰ 急性心肌梗死 预后 Cardiac Troponin I (cTnI) Acute myocardial in farction (AMI) Prognosis.
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