摘要
目的 探讨血液灌流 (HP)治疗重度毒鼠强中毒的疗效。方法 将 1999年 1月～ 2 0 0 2年 12月重度毒鼠强中毒 4 8例患儿分HP组和常规组。常规组采用洗胃、导泻、止痉、降颅内压、二巯基丙磺酸钠综合治疗 ;HP组在综合治疗基础上加用HP治疗。结果 HP组抢救成功例数高于常规组 (χ2 =8.17 P <0 .0 1)。HP组较常规组更能明显缩短患儿抽搐时间 (t =11.0 0 P <0 .0 1)、昏迷时间 (t =9.32 P <0 .0 1)、住院时间 (t =3.6 7 P <0 .0 1) ,且在中毒 6h内行HP治疗者 ,存活率明显增加。
Objective To investigate the clinical significance of hemoperfusion(HP) in treating severe tetramine intoxication.Methods Fourty-eight children with severe tetramine intoxication from January 1999 to December 2002 were enrolled into two groups:HP treatment group and routine treatment group. Routine treatment group was treated with general therapy,such as gastrdavage,catharsis and so on. While hemoperfusion was added to HP treatment group besides general therapy.Results The number of cure in HP treatment group was higher than that in routine treatment group(χ 2=8.17 P<0.01),meanwhile the time of tic(t= 11.00 P<0.01),coma(t=9.32 P<0.01) and the time of hospitalization (t=3.67 P<0.01) in HP treatment group were significantly shorter than those of routine treatment group. Furthermore the children with intoxication in six hours were treated with hemoperfusion,the survival rate was obviously increased.Conclusion HP is an efficient treatment in severe tetramine intoxication.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2004年第4期267-268,共2页
Journal of Applied Clinical Pediatrics
关键词
血液灌流
毒鼠强
中毒
hemoperfusion
tetramine
intoxication
